O-(3-methoxy-4-pent-2-ynyloxy-benzylbenzyl)-hydroxylamine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: O-(3-methoxy-4-pent-2-ynyloxy-benzylbenzyl)-hydroxylamine
• 英文别名: O-(3-methoxy-4-pent-2-ynyloxy-benzyl)-hydroxylamine；O-[(3-methoxy-4-pent-2-ynoxyphenyl)methyl]hydroxylamine
• 化学式: C₁₃H₁₇NO₃
• 分子量: 235.283
• InChiKey: RWSSDUWAWLRXPE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  53.7
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  O-(3-methoxy-4-pent-2-ynyloxy-benzylbenzyl)-hydroxylamine 、 对氯扁桃酸 在 (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate 、 N,N-二异丙基乙胺 作用下， 以 DMF (N,N-dimethyl-formamide) 为溶剂， 反应 16.0h， 生成 2-(4-chloro-phenyl)-2-hydroxy-N-(3-methoxy-4-pent-2-ynyloxy-benzyloxy)-acetamide
  参考文献：
  名称：

  [EN] PROPARGYLETHER DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE FOR CONTROLLING PHYTOPATHOGENIC MICROORGANISMS
  [FR] NOUVEAUX DERIVES DE PROPARGYLETHER POUR LA LUTTE CONTRE LES MICROORGANISMES PHYTOPATHOGENES

  摘要：

  公开号：

  WO2004033413A3
• 作为产物：
  描述：

  2-(3-methoxy-4-pent-2-ynyloxy-benzyloxy)-isoindole-1,3-dione 在 肼 作用下， 以 甲醇 、 DMF (N,N-dimethyl-formamide) 为溶剂， 反应 3.0h， 生成 O-(3-methoxy-4-pent-2-ynyloxy-benzylbenzyl)-hydroxylamine
  参考文献：
  名称：

  [EN] PROPARGYLETHER DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE FOR CONTROLLING PHYTOPATHOGENIC MICROORGANISMS
  [FR] NOUVEAUX DERIVES DE PROPARGYLETHER POUR LA LUTTE CONTRE LES MICROORGANISMES PHYTOPATHOGENES

  摘要：

  公开号：

  WO2004033413A3

文献信息

• Propargylether derivatives, a process for their preparation and their use for controlling phytopathogenic microorganisms
  申请人：Lamberth Clemens

  公开号：US20060167316A1

  公开（公告）日：2006-07-27

  The invention relates to 4-propargyloxy-benzyl dervatives of the general formula (I) including the optical isomers thereof and mixtures of such isomers, wherein R 1 is hydrogen, optionally substituted alkyl, optionally substituted cycloalkyl or optionally substituted aryl; R 2 , R 3 , R 5 , R 6 , and R 7 are each independently of each other hydrogen or optionally substituted alkyl; R 4 is optionally substituted alkyl; X is O or N—R 7 ; and R 8 is a group R 9 is optionally substituted aryl or optionally substituted heteroaryl; R 10 and R 11 , are each independently hydrogen, optionally substituted alkyl, optionally substituted alkenyl or optionally substituted alkynyl; R 12 is optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted aryl or optionally substituted heteroaryl; R 13 is hydrogen or optionally substituted alkyl, alkenyl or alkynyl; and R 14 is optionally substituted alkyl or optionally substituted amino. These compounds possess useful plant protecting properties and may advantageously be employed in agricultural practice for controlling or preventing the infestation of plants by phytopathogenic microorganisms, especially fungi.

  本发明涉及一般式（I）的4-丙炔氧基苄基衍生物，包括其光学异构体和这些异构体的混合物，其中R1为氢、可选取代烷基、可选取代环烷基或可选取代芳基；R2、R3、R5、R6和R7各自独立地为氢或可选取代烷基；R4为可选取代烷基；X为O或N-R7；R8为R9为可选取代芳基或可选取代杂环芳基；R10和R11各自独立地为氢、可选取代烷基、可选取代烯基或可选取代炔基；R12为可选取代烷基、可选取代环烷基、可选取代芳基或可选取代杂环芳基；R13为氢或可选取代烷基、烯基或炔基；R14为可选取代烷基或可选取代氨基。这些化合物具有有用的植物保护性能，并可有利地用于农业实践中，以控制或预防植物受植物病原微生物，特别是真菌的侵害。
• PROPARGYLETHER DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE FOR CONTROLLING PHYTOPATHOGENIC MICROORGANISMS
  申请人：Syngenta Participations AG

  公开号：EP1549609B1

  公开（公告）日：2007-01-24
• US7189873B2
  申请人：——

  公开号：US7189873B2

  公开（公告）日：2007-03-13
• [EN] PROPARGYLETHER DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE FOR CONTROLLING PHYTOPATHOGENIC MICROORGANISMS<br/>[FR] NOUVEAUX DERIVES DE PROPARGYLETHER POUR LA LUTTE CONTRE LES MICROORGANISMES PHYTOPATHOGENES
  申请人：SYNGENTA PARTICIPATIONS AG

  公开号：WO2004033413A3

  公开（公告）日：2004-06-10