2-((([1,1'-biphenyl]-2-ylimino)methylene)amino)benzonitrile | 1565834-76-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-((([1,1'-biphenyl]-2-ylimino)methylene)amino)benzonitrile
• CAS: 1565834-76-5
• 化学式: C₂₀H₁₃N₃
• 分子量: 295.343
• InChiKey: QPVAMMCTZZBEJN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  23
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  48.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-((([1,1'-biphenyl]-2-ylimino)methylene)amino)benzonitrile 在 三甲基氯硅烷 作用下， 以 二氯甲烷 为溶剂， 以78%的产率得到3-([1,1'-biphenyl]-2-yl)-2-chloroquinazolin-4(3H)-iminium chloride
  参考文献：
  名称：

  One-Pot Cascade Approach to Phenanthridine-Fused Quinazoliniminiums from Heteroenyne-Allenes

  摘要：

  A one-pot cascade method to obtain functionalized phenanthridine-fused quinazoliniminiums from a variety of heteroenyne-allenes is described. This protocol involves formation of C-N and C-C bonds in a single step in the presence of a Lewis acid and trace water to afford pentacyclic title compounds in moderate to good yields.

  DOI：

  10.1021/ol500314x
• 作为产物：
  描述：

  2-氨基苯甲腈 在 三乙胺 作用下， 以 二氯甲烷 、 甲苯 为溶剂， 生成 2-((([1,1'-biphenyl]-2-ylimino)methylene)amino)benzonitrile
  参考文献：
  名称：

  One-Pot Cascade Approach to Phenanthridine-Fused Quinazoliniminiums from Heteroenyne-Allenes

  摘要：

  A one-pot cascade method to obtain functionalized phenanthridine-fused quinazoliniminiums from a variety of heteroenyne-allenes is described. This protocol involves formation of C-N and C-C bonds in a single step in the presence of a Lewis acid and trace water to afford pentacyclic title compounds in moderate to good yields.

  DOI：

  10.1021/ol500314x

文献信息

• One-Pot Cascade Approach to Phenanthridine-Fused Quinazoliniminiums from Heteroenyne-Allenes
  作者：Olajide E. Alawode、Vijaya Kumar Naganaboina、Thakshila Liyanage、John Desper、Sundeep Rayat

  DOI：10.1021/ol500314x

  日期：2014.3.7

  A one-pot cascade method to obtain functionalized phenanthridine-fused quinazoliniminiums from a variety of heteroenyne-allenes is described. This protocol involves formation of C-N and C-C bonds in a single step in the presence of a Lewis acid and trace water to afford pentacyclic title compounds in moderate to good yields.