N,N,N',N'-tetracyclohexyl-2,2'-biphenyldicarboxamide | 110926-83-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N,N,N',N'-tetracyclohexyl-2,2'-biphenyldicarboxamide
• 英文别名: N,N-dicyclohexyl-2-[2-(dicyclohexylcarbamoyl)phenyl]benzamide
• CAS: 110926-83-5
• 化学式: C₃₈H₅₂N₂O₂
• 分子量: 568.843
• InChiKey: KDENVQZUIOWUSY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.2
• 重原子数：
  42
• 可旋转键数：
  7
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.63
• 拓扑面积：
  40.6
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  四氢呋喃 、 N,N,N',N'-tetracyclohexyl-2,2'-biphenyldicarboxamide 生成 Biphenyl-2,2'-dicarboxylic acid bis-dicyclohexylamide; compound with tetrahydro-furan
  参考文献：
  名称：

  A Novel Host Compound with High Inclusion Ability,N,N,N′,N′-Tetracyclohexyl-2,2′-biphenyldicarboxamide, and Crystal Structure of Its 1:1 Phenol Complex

  摘要：

  标题宿主化合物与多种有机客体分子形成结晶包合物复合物。对其与苯酚的1:1复合物进行X射线分析显示，两个分子成分通过一个长度为2.59(1) Å 的O–H···O氢键相互结合。

  DOI：

  10.1246/cl.1987.1393
• 作为产物：
  描述：

  2,2'-联苯二甲酸 在 五氯化磷 作用下， 以 苯 为溶剂， 生成 N,N,N',N'-tetracyclohexyl-2,2'-biphenyldicarboxamide
  参考文献：
  名称：

  A Novel Host Compound with High Inclusion Ability,N,N,N′,N′-Tetracyclohexyl-2,2′-biphenyldicarboxamide, and Crystal Structure of Its 1:1 Phenol Complex

  摘要：

  标题宿主化合物与多种有机客体分子形成结晶包合物复合物。对其与苯酚的1:1复合物进行X射线分析显示，两个分子成分通过一个长度为2.59(1) Å 的O–H···O氢键相互结合。

  DOI：

  10.1246/cl.1987.1393
• 作为试剂：
  描述：

  Brenztraubensaeuredimethylamid 在 N,N,N',N'-tetracyclohexyl-2,2'-biphenyldicarboxamide 作用下， 以 solid 为溶剂， 反应 40.0h， 生成 3-Hydroxy-1,3-dimethyl-azetidin-2-one
  参考文献：
  名称：

  Toda, Fumio; Tanaka, Koichi; Yagi, Minoru, Journal of the Chemical Society. Perkin transactions I, 1990, # 4, p. 1215 - 1216

  摘要：

  DOI：

文献信息

• Highly selective photoreactions of α-oxoamides and α-tropolone alkyl ethers in crystalline inclusion complexes
  作者：Fumio Toda、Koichi Tanaka、Minoru Yagi

  DOI：10.1016/s0040-4020(01)90265-0

  日期：1987.1

  Control of photocyclization of three α-oxoamides in crystalline inclusion complexes with three kinds of host compounds was studied. In all cases, β-lactams were obtained exclusively. In two cases, cis-β-lactams were formed selectively. By an enantioselective control using an optically active host compound, 1,6-di(o-chlorophenyl)-1,6-diphenylhexa-2, 4-diyne-l,6-diol, optically active β-lactams of high

  研究了与三种主体化合物的结晶包合物中三种α-氧代酰胺的光环化作用。在所有情况下，仅获得β-内酰胺。在两种情况下，选择性地形成顺式-β-内酰胺。通过使用光学活性主体化合物1,6-二（邻-氯苯基）-1,6-二苯基己-2，4-二炔-1,6-二醇的对映选择性控制，得到高对映体过量的光学活性β-内酰胺。获得。用固态的上述旋光主体化合物辐照α-四氢呋喃烷基醚的配合物，得到[2 + 2]光反应产物1-烷氧基双环[3.2.0] hepta-3,6-dien-2-one ，及其开环衍生物4-氧代-2-环戊烯-1-乙酸烷基酯，分别对映体过量100和72-91％。
• Method of purifying a microbicide by separating the microbicide from a clathrate compound
  申请人：Kurita Water Industries Ltd.

  公开号：EP0326261A2

  公开（公告）日：1989-08-02

  A clathrate compound is produced if a powdery host compound which reacts with a microbicide to form the clathrate compound is added into an aqueous solution of the microbicide. If the microbicide is separated from the clathrate compound, a microbicide of high purity can be obtained.

  如果在杀微生物剂的水溶液中加入粉末状宿主化合物，这种粉末状宿主化合物就会与杀微生物剂发生反应，形成凝块化合物。如果将杀微生物剂与凝块化合物分离，就可以得到高纯度的杀微生物剂。
• Antimicrobial composition
  申请人：KURITA WATER INDUSTRIES LTD.

  公开号：EP0332336A3

  公开（公告）日：1991-08-07

  An antimicrobial composition comprises a clathrate compound containing a water-soluble microbicide, and a dispersion medium. The microbicide may be 5-chloro-2-methyl-4-isothiazoline-3-one and the host compound may be (1) 1,1,6,6-tetraphenyl-2,4-hexadiyne-1,6-diol;(2) 1,1-di(2,4-dimethylphenyl)-2-propyne-1-ol;(3) 1,1,4,4-tetraphenyl-2-butyne-1,4-diol;(4) 1,1'-bi-2-naphthol;(5) 1,1,6,6-tetra(2,4-dimethylphenyl)-2,4-hexadiyne-1,6-diol;(6) 9,10-di(4-methylphenyl)-9,10-dihydroanthracene-9,10-diol;(7) 1,1-bis(4-hydroxyphenyl)cyclohexane;(8) N,N,N',N'-tetra(cyclohexyl)-[1,1'-biphenyl]-2,2'-dicarboxyamide;(9) 2,2'-methylenebis(4-chlorophenol);(10) deoxycholic acid; and(11) 2,5-di-tert-butylhydroquinone.

  一种抗微生物组合物由含有水溶性杀微生物剂的凝块化合物和分散介质组成。杀微生物剂可以是 5-氯-2-甲基-4-异噻唑啉-3-酮，宿主化合物可以是 (1) 1,1,6,6-tetraphenyl-2,4-hexadiyne-1,6-diol;(2) 1,1-di(2,4-dimethylphenyl)-2-propyne-1-ol;(3) 1,1,4,4-tetraphenyl-2-butyne-1,4-diol;(4) 1,1'-bi-2-naphthol;(5) 1,1,6,6-tetra(2,4-dimethylphenyl)-2,4-hexadiyne-1,6-diol;(6) 9,10-二(4-甲基苯基)-9,10-二氢蒽-9,10-二醇； (7) 1,1-双(4-羟基苯基)环己烷；(8) N,N,N',N'-四(环己基)-[1,1'-联苯]-2,2'-二羧酰胺；(9) 2,2'-亚甲基双(4-氯苯酚)；(10) 脱氧胆酸；以及(11) 2,5-二叔丁基对苯二酚。
• Antimicrobial composition and their use
  申请人：KURITA WATER INDUSTRIES LTD.

  公开号：EP0923867A1

  公开（公告）日：1999-06-23

  An antimicrobial composition is provided in which the skin irritation of isothiazolone type compound is decreased and the injection operation properties thereof is improved by forming it as an uniform solution. The composition contains isothiazolone type compound and a compound which decreases the skin irritation of the former in a molar ratio of 1:0.1-50 and is dissolved in a solvent.

  本发明提供了一种抗菌剂组合物，通过将其制成均匀溶液，降低了异噻唑啉酮类化合物对皮肤的刺激性，并改善了其注射操作性能。该组合物含有异噻唑啉酮类化合物和一种可降低前者对皮肤刺激性的化合物，两者的摩尔比为 1:0.1-50，并溶解在溶剂中。
• SLIME REMOVER AND SLIME PREVENTING/REMOVING AGENT
  申请人：NIPPON SODA CO., LTD.

  公开号：EP1113112A1

  公开（公告）日：2001-07-04

  A drainage slime remover capable of spreading a solution of a solid over slime generated wall surface portions, comprising a solid containing a microorganism growth retarding substance and a container which has a shape for permitting the installation thereof at the inlet or upper portion of a drain outlet and stores the solid characterized in that the container has drain flow-in holes having an opening capable of controlling a drain flow-in amount and provided in the upper surface or the upper side portion of the container and solution flow-out holes having an opening capable of controlling a flow-out amount of a solid solution and provided in the bottom or the lower side portion of the container or additionally in the side surface thereof, and a slime preventing/removing agent which can remove slime from portions such as kitchen sinks and bathroom drain outlets where slime is grown by metabolites such as miscellaneous germs and mildews and which can prevent the occurrence of slime safely and for an extended period of time.

  一种排水粘泥清除器，能够将固体溶液撒在产生粘泥的墙壁表面部分、包括含有微生物生长抑制物质的固体和容器，容器的形状允许将其安装在排水口的入口或上部，并储存固体，其特征在于，容器的上表面或上侧部分设有排水流入孔，该孔具有能够控制排水流入量的开口，容器的底部或下侧部分或其侧表面还设有溶液流出孔，该孔具有能够控制固体溶液流出量的开口、以及一种粘液防止/清除剂，它可以清除厨房水槽和浴室下水道口等地方的粘液，因为在这些地方，各种病菌和霉菌等代谢物会滋生粘液，它可以安全并长时间地防止粘液的产生。