2-hydroxy-2-isobutyl-4-methyl-valeric acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-hydroxy-2-isobutyl-4-methyl-valeric acid
• 英文别名: C.C-Diisobutyl-glykolsaeure；4-Hydroxy-2.6-dimethyl-heptan-capronsaeure-(4)；2-Hydroxy-2-isobutyl-4-methyl-valeriansaeure；2-Hydroxy-4-methyl-2-(2-methylpropyl)pentanoic acid；2-hydroxy-4-methyl-2-(2-methylpropyl)pentanoic acid
• 化学式: C₁₀H₂₀O₃
• 分子量: 188.267
• InChiKey: ALSAHIUAUWBKFQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  二异丁基酮 在 哌啶 、 盐酸 作用下， 生成 2-hydroxy-2-isobutyl-4-methyl-valeric acid
  参考文献：
  名称：

  5,5-Dialkyl-2,4-oxazolidinediones^1,2

  摘要：

  DOI：

  10.1021/ja01854a019

文献信息

• Basse; Klinger, Chemische Berichte, 1898, vol. 31, p. 1220
  作者：Basse、Klinger

  DOI：——

  日期：——
• POLYMERIC MATERIALS FOR BIO-APPLICATIONS
  申请人：The Brigham and Women's Hospital, Inc.

  公开号：US20170051099A1

  公开（公告）日：2017-02-23

  A composition comprising a biodegradable polymeric material and therapeutic agent associated with the polymeric material that advantageously can provide controlled release of the therapeutic agent, while comprising little to no auxiliary materials. In some embodiments, the composition is formed by the reaction of one or more monomers in the presence of a food grade catalyst. In another embodiment, the composition comprises a polymeric material capable of undergoing thermal reconfiguration (i.e. a dynamic network). Advantageously, the compositions and materials described herein may comprise a reconfigurable polymeric material (e.g., a thermoset polymeric material) having the strength and integrity of epoxy resins, the biomedical applicability of hydrogels, and/or the moldability of vitrimers.
• 5,5-Dialkyl-2,4-oxazolidinediones^1,2
  作者：Roger W. Stoughton

  DOI：10.1021/ja01854a019

  日期：1941.9