A Lewis-acid-promoted approach to the synthesis of highly functionalized dihydrobenzofuranderivatives was developed. A diverse range of functional groups are tolerated in this type of reaction. The reaction mechanism investigation indicates that the highly reactive phenyl cation intermediate is probably involved in this process. The chirality of substrate is retained under the reaction conditions
A Simple and Efficient Synthesis of Dibenzothiophene via BF3·OEt2-Promoted Intramolecular Annulation
作者:Wanzhi Chen、Yingming Yao、Xiaobo Shang
DOI:10.1055/s-0032-1318391
日期:——
A simple and efficient protocol promoted by BF3 center dot OEt2 for synthesizing functionalized dibenzothiophenes (DBTs) has been demonstrated. The annulation condition can tolerate a variety of functional groups.