P-benzyl-N,N,N',N'-tetraethylphosphonothioic diamide | 183874-07-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: P-benzyl-N,N,N',N'-tetraethylphosphonothioic diamide
• 英文别名: Benzylbis(diethylamino)phosphine sulfide；N-[benzyl(diethylamino)phosphinothioyl]-N-ethylethanamine
• CAS: 183874-07-9
• 化学式: C₁₅H₂₇N₂PS
• 分子量: 298.433
• InChiKey: DCEFAVDHYMDUMQ-UHFFFAOYSA-N

物化性质

• 沸点：
  383.6±35.0 °C(Predicted)
• 密度：
  1.049±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  19
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  38.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  P-Benzyl-N,N,N',N'-tetraethylphosphonous diamide 在 1,2,3,4,5,6,7,8-八硫杂环辛烷 作用下， 以 甲苯 为溶剂， 反应 1.0h， 以0.15 g的产率得到P-benzyl-N,N,N',N'-tetraethylphosphonothioic diamide
  参考文献：
  名称：

  An Unconventional Synthesis of Dibromophosphines

  摘要：

  Dibromophosphines, RPBr2, are obtained by reaction of tetrabromomethane with 7-substituted 7-phosphanorbornenes in toluene at ca. 100 degrees C. The phosphanorbornenes are obtained in situ by cycloaddition of N-phenylmaleimide with 1-substituted 3,4-di-methylphospholes. The overall reaction sequence shows a good compatibility with functional groups.

  DOI：

  10.1055/s-0033-1339548

文献信息

• Nucleophilic substitution in benzylic phosphonothioic dichlorides formation of a diamide without intervention of the amidic chloride
  作者：Martin J.P. Harger

  DOI：10.1016/0040-4039(96)01880-1

  日期：1996.11

  The diamide RP(S)(NEt2)2 (R = PhCH2 or Ph2CH) is formed directly from the dichloride RP(S)Cl2 more quickly than it is from the amidic chloride RP(S)(NEt2)Cl

  直接由二氯化物RP（S）Cl 2形成二酰胺RP（S）（NEt 2）2（R = PhCH 2或Ph 2 CH）比由氯化酰胺RP（S）（NEt 2）更快地形成二酰胺RP（S）（NEt 2）2氯
• Sinyashin, O.G.; Karimullin, Sh. A.; Kostin, V. P., Journal of general chemistry of the USSR, 1986, vol. 56, p. 1505 - 1511
  作者：Sinyashin, O.G.、Karimullin, Sh. A.、Kostin, V. P.、Batyeva, E. S.、Pudovik, A. N.

  DOI：——

  日期：——
• An Unconventional Synthesis of Dibromophosphines
  作者：Zheng Duan、François Mathey、Lili Wang、Lujun Zhang、Hanyu Shi

  DOI：10.1055/s-0033-1339548

  日期：——

  Dibromophosphines, RPBr2, are obtained by reaction of tetrabromomethane with 7-substituted 7-phosphanorbornenes in toluene at ca. 100 degrees C. The phosphanorbornenes are obtained in situ by cycloaddition of N-phenylmaleimide with 1-substituted 3,4-di-methylphospholes. The overall reaction sequence shows a good compatibility with functional groups.