| 1310353-08-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• CAS: 1310353-08-2
• 化学式: C₁₁H₁₄OS₃
• 分子量: 258.43
• InChiKey: NIINPCHWHBFYIU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.45
• 重原子数：
  15.0
• 可旋转键数：
  4.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  20.23
• 氢给体数：
  1.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  、 3,5-双(三氟甲基)苯基异氰酸酯 在 二月桂酸二丁基锡 作用下， 以 四氢呋喃 为溶剂， 生成 [4-(ethylsulfanylcarbothioylsulfanylmethyl)phenyl]methyl N-[3,5-bis(trifluoromethyl)phenyl]carbamate
  参考文献：
  名称：

  用电子显微镜对分层结构进行无污染可视化的简便方法

  摘要：

  二嵌段共聚物形成分级形态，在药物递送中和作为纳米反应器具有大量应用。然而，通过电子显微镜对这些结构进行可视化可能非常困难，需要复杂的染色技术以及相关的健康风险和改变结构形态的潜力。此处报道的是通过RAFT合成的含3,5-双（三氟甲基）苯基官能团的二嵌段共聚物，无需进一步制备样品即可通过TEM轻松观察其最终的分层结构。

  DOI：

  10.1002/pola.27517
• 作为产物：
  描述：

  二硫化碳 、 乙醇 、 4-(氯甲基)苯甲基醇 在 potassium phosphate 作用下， 以 丙酮 为溶剂， 生成
  参考文献：
  名称：

  Postpolymerization Modification of Hydroxyl-Functionalized Polymers with Isocyanates

  摘要：

  The postpolymerization functionalization of hydroxyl-group terminated polymers (M-n in the range of 1000-6000 g mol(-1)) such as poly(ethylene glycol) (PEG), poly(N-isopropylacrylamide) (PNIPAM), poly(N,N-dimethylacrylamide) (PDMAM), and poly(tert-butyl acrylate) (PtBA) with a wide range of functional isocyanate derivatives such as azobenzene, and anthracene has been investigated. It was shown by H-1 and C-13 NMR, GPC, Fourier transform infrared spectroscopy (FTIR), and electrospray ionization mass spectrometry (ESI-MS) that a high degree of end-group conversion, typically >98%, with little or no formation of side products can be achieved at ambient temperature. PNIPAM, PDMAM, PtBA, and PHEAM polymers have been obtained by reversible addition-fragmentation chain transfer (RAFT) radical polymerization from a hydroxyl-group containing chain transfer agent (CTA). The formation of the carbamate has been shown to be compatible with the trithiocarbonate end-group of the RAFT polymers. Additionally, this approach allows for the direct functionalization of RAFT polymers without the need of additional steps such as deprotection or aminolysis of the CTA. This route was subsequently used for the preparation of a variety of side-chain functional polymers from poly(N-hydroxyethyl acrylamide) (PHEAM). Three different high yielding methods have been employed to prepare the isocyanates (R-NCO). Either amino or carboxylic acid precursors have been converted into the desired R NCO or hydroxyl group moieties have been reacted with an excess of 1,6-hexamethylene diisocyanate (HDI) to statistically form the monofunctional product.

  DOI：

  10.1021/ma2008018