2,2'-(3-(allyloxy)-2-hydroxypropylazanediyl)diacetic acid | 177217-92-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2,2'-(3-(allyloxy)-2-hydroxypropylazanediyl)diacetic acid
• 英文别名: 2-[Carboxymethyl-(2-hydroxy-3-prop-2-enoxypropyl)amino]acetic acid
• CAS: 177217-92-4
• 化学式: C₁₀H₁₇NO₆
• 分子量: 247.248
• InChiKey: VCAQYWPWCPQMJJ-UHFFFAOYSA-N

物化性质

• 沸点：
  493.3±45.0 °C(Predicted)
• 密度：
  1.305±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -2.9
• 重原子数：
  17
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  107
• 氢给体数：
  3
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  烯丙基缩水甘油醚 、 亚氨基二乙酸 在 potassium hydroxide 作用下， 以 水 为溶剂， 反应 1.0h， 生成 2,2'-(3-(allyloxy)-2-hydroxypropylazanediyl)diacetic acid
  参考文献：
  名称：

  Synthesis and characterization of new molecular imprinting poly[1-(N,N-bis-carboxymethyl)amino-3-allylglycerol-co-dimethylacrylamide] for selective sorption and determination of cefuroxime sodium in biological and pharmaceutical samples

  摘要：

  Two molecular imprinting polymers (MIPs) based on solution and suspension polymerization were prepared with 1-(N,N-bis-carboxymethyl)amino-3-allylglycerol and N,N-dimethylacrylamide as functional monomers, and copper ion-cefuroxime sodium complex as the template. The imprinted polymers were characterized by Fourier transform infrared spectroscopy, thermogravimetric analysis, elemental analysis, Brunauer, Emmett and Teller method and scanning electron microscopy. The effects of the analytical parameters such as sample pH, contact time on sorption capacity of the polymeric sorbent and interfering drugs were investigated and compared for both polymers with different polymerization methods. The imprinted polymer sorbent was selective for the template. The profile of cefuroxime sodium uptake by the both sorbents reflects good accessibility of the active sites in the imprinted polymer sorbents. The equilibrium adsorption data of cefuroxime sodium on polymeric sorbents were analyzed by Langmuir, Freundlich, Temkin and Redlich-Peterson isotherm models. The developed method was utilized for determination of cefuroxime sodium in pharmaceutical and fluids biological samples like human plasma and urine by high performance liquid chromatography with satisfactory results. (c) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.reactfunctpolym.2012.08.021

文献信息

• Amino Group-Containing Water-Soluble Copolymer
  申请人：Yoneda Atsuro

  公开号：US20080262192A1

  公开（公告）日：2008-10-23

  To provide an amino group-containing water-soluble copolymer having a high chelating performance and clay dispersancy and a method of producing the amino-group containing water-soluble copolymer efficiently and with high productivity. A water-soluble polymer containing an amino group-containing monomer unit, wherein the water-soluble polymer has a molecular weight distribution of 12 or less, and a method of producing the water-soluble polymer according to any one of claims 1 to 4, wherein the method comprises a step of polymerizing an amino group-containing allyl monomer using an initiator containing a heavy metal ion and sulfurous acid (sulfite), hydrogensulfite or hydrogen peroxide.

  提供一种具有高螯合性和黏土分散性的含氨基水溶性共聚物以及高效生产含氨基水溶性共聚物的方法。其中，所述含氨基单体单元的水溶性聚合物具有分子量分布为12或以下，生产所述水溶性聚合物的方法包括使用含有重金属离子和亚硫酸（亚硫酸盐）、亚硫酸氢盐或过氧化氢的引发剂聚合含氨基烯丙单体的步骤。
• COATING COMPOSITIONS HAVING CHELANT FUNCTIONALITY
  申请人：Rohm and Haas Company

  公开号：EP2807221B1

  公开（公告）日：2016-04-06
• (METH) ACRYLIC ACID-BASED COPOLYMER, METHOD FOR PRODUCING THE SAME AND DETERGENT COMPOSITION USING THE SAME
  申请人：Yoneda Atsuro

  公开号：US20110183880A1

  公开（公告）日：2011-07-28

  The present invention provides a (meth)acrylic acid-based copolymer useful to a detergent which is excellent in efficient removal capability of soil of clothes (in particular, hydrophobic soil such as collar dirt or greasy dirt), and prevention capability of soil redeposition, not to re-adhere the soil to laundries, even in carrying out washing with small amount of water. The present invention provides a (meth)acrylic acid-based copolymer comprising, as repeating units: a repeating unit (a) derived from a (meth)acrylic acid-based monomer (A) represented by the formula (1); and a repeating unit (b) derived from an alkyl(meth)acrylate-based monomer (B) represented by the formula (2) or a repeating unit (c) derived from a vinyl aromatic-based monomer (C); and 1 or, 2 or more kinds of repeating units (d) selected from the group consisting of a repeating unit (d-1) derived from an unsaturated monomer (D-1) represented by the formula (3), a repeating unit (d-2) derived from an unsaturated monomer (D-2) represented by the formula (4) a repeating unit (d-3) derived from a hydroxyalkyl(meth)acrylate-based monomer (D-3) represented by the formula (5), and a repeating unit (d-4) derived from a sulfonic acid group containing monomer (D-4) represented by the formula (6). Furthermore, the present invention provides a method for producing said (meth)acrylic acid-based copolymer.
• US5994110A
  申请人：——

  公开号：US5994110A

  公开（公告）日：1999-11-30
• US8106149B2
  申请人：——

  公开号：US8106149B2

  公开（公告）日：2012-01-31