N-(6-aminohexyl)-4-(pyren-4-yl)butanamide hydrochloride | 1189164-58-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 芘
• 英文名称: N-(6-aminohexyl)-4-(pyren-4-yl)butanamide hydrochloride
• 英文别名: N-(6-aminohexyl)-4-(pyren-4-yl)butanamide
• CAS: 1189164-58-6
• 化学式: C₂₆H₃₀N₂O
• 分子量: 386.537
• InChiKey: ARNCJQIYMYXSBA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.54
• 重原子数：
  29.0
• 可旋转键数：
  10.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  55.12
• 氢给体数：
  2.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  N-(6-aminohexyl)-4-(pyren-4-yl)butanamide hydrochloride 、 phenyl 2-azido-3,6-di-O-benzyl-4-O-(2-carboxyethyl)-2-deoxy-1-thio-α-D-glucopyranoside 在 O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate 、 N,N-二异丙基乙胺 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 44.0h， 以83%的产率得到
  参考文献：
  名称：

  A latent reactive handle for functionalising heparin-like and LMWH deca- and dodecasaccharides

  摘要：

  含有O4处潜在醛代用基的二糖单元可实现对末端醛基低分子肝素（LMWH）和硫酸肝素（HS）十聚体和十二聚体糖的后期访问。

  DOI：

  10.1039/c5ob01706h
• 作为产物：
  描述：

  1-芘丁酸 在 盐酸 、 O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate 、 N,N-二异丙基乙胺 作用下， 以 四氢呋喃 、 水 、 N,N-二甲基甲酰胺 为溶剂， 反应 27.0h， 生成 N-(6-aminohexyl)-4-(pyren-4-yl)butanamide hydrochloride
  参考文献：
  名称：

  A latent reactive handle for functionalising heparin-like and LMWH deca- and dodecasaccharides

  摘要：

  含有O4处潜在醛代用基的二糖单元可实现对末端醛基低分子肝素（LMWH）和硫酸肝素（HS）十聚体和十二聚体糖的后期访问。

  DOI：

  10.1039/c5ob01706h

文献信息

• Temperature Controlled Dispersion of Carbon Nanotubes in Water with Pyrene-Functionalized Poly(<i>N</i>-cyclopropylacrylamide)
  作者：Krishna C. Etika、Florian D. Jochum、Patrick Theato、Jaime C. Grunlan

  DOI：10.1021/ja905803f

  日期：2009.9.30

  Despite their immense potential, the ability to control the dispersion and microstructure of carbon nanotubes remains a hurdle for their widespread use. Poly(N-cyclopropylacrylamide), containing 5 mol% pyrene-bearing repeat units (p-PNCPA), is shown to vary the dispersion state of single-waited carbon nanotubes (SWNTs) in water. This is a thermo-responsive polymer whose conformation changes with temperature, which in turn leads to changes in the nanotube dispersion state. Cryo-TEM micrographs show that SWNTs stabilized using p-PNCPA transitions from a more exfoliated to a more bundled state as the aqueous suspension temperature is raised above the Lower critical solution temperature (LCST) of the polymer (similar to 30 degrees C). Viscosity measurements on SWNT/p-PNCPA aqueous suspensions show shear thinning and near Newtonian behavior at 10 and 50 degrees C, respectively. Drying of these suspensions produces composites whose microstructure and electrical conductivity vary with drying temperature. This behavior has significant implications for the processing of carbon nanotubes and tailoring of composite properties. Such stimuli-controlled dispersion of carbon nanotubes could have a variety of applications in nanoelectronics, sensing, and drug and gene delivery systems.