2-[2-[2-Hydroxy-3-(2-hydroxyphenyl)phenyl]-3,4,5,6-tetraphenylphenyl]-6-(2-hydroxy-3-iodophenyl)phenol | 1332305-60-8

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二芳基庚烷
• 英文名称: 2-[2-[2-Hydroxy-3-(2-hydroxyphenyl)phenyl]-3,4,5,6-tetraphenylphenyl]-6-(2-hydroxy-3-iodophenyl)phenol
• CAS: 1332305-60-8
• 化学式: C₅₄H₃₇IO₄
• 分子量: 876.79
• InChiKey: YOACSSOJCWHBDN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  14.2
• 重原子数：
  59
• 可旋转键数：
  8
• 环数：
  9.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  80.9
• 氢给体数：
  4
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-[2-[2-Hydroxy-3-(2-hydroxyphenyl)phenyl]-3,4,5,6-tetraphenylphenyl]-6-(2-hydroxy-3-iodophenyl)phenol 在 正丁基锂 、 水 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 反应 0.17h， 以96%的产率得到2-[2-[2-Hydroxy-3-(2-hydroxyphenyl)phenyl]-3,4,5,6-tetraphenylphenyl]-6-(2-hydroxyphenyl)phenol
  参考文献：
  名称：

  Synthesis of three-dimensionally arranged bis-biphenol ligand on hexaaryl benzene scaffold and its application for cross-pinacol coupling reaction

  摘要：

  The three-dimensionally arranged bis-biphenol ligand on a hexaaryl benzene scaffold for a dinuclear complex was synthesized by the Diels-Alder addition-decarbonylation reaction as a key step. Its preliminary studies on the titanium-induced cross-pinacol coupling reaction were performed based on step-by-step activation of two different aldehydes. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.06.113
• 作为产物：
  描述：

  3,3'-Diiodo-2,2'-dimethoxy-1,1'-biphenyl 在 bis-triphenylphosphine-palladium(II) chloride 、 copper(l) iodide 、 三溴化硼 、 三乙胺 作用下， 以 二苯醚 、 二氯甲烷 为溶剂， 反应 40.17h， 生成 2-[2-[2-Hydroxy-3-(2-hydroxyphenyl)phenyl]-3,4,5,6-tetraphenylphenyl]-6-(2-hydroxy-3-iodophenyl)phenol
  参考文献：
  名称：

  Synthesis of three-dimensionally arranged bis-biphenol ligand on hexaaryl benzene scaffold and its application for cross-pinacol coupling reaction

  摘要：

  The three-dimensionally arranged bis-biphenol ligand on a hexaaryl benzene scaffold for a dinuclear complex was synthesized by the Diels-Alder addition-decarbonylation reaction as a key step. Its preliminary studies on the titanium-induced cross-pinacol coupling reaction were performed based on step-by-step activation of two different aldehydes. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.06.113