2,2'-thiobis<4-t-butylphenol> | 3273-24-3

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 2,2'-thiobis<4-t-butylphenol>
• 英文别名: 4,4'-di(tert-butyl)-2,2'-sulfandiyldiphenol；bis(2-hydroxy-5-tert-butylphenyl) sulfide；bis(5-t-butyl-2-hydroxyphenyl)sulfide；2,2'-thiobis(4-tert-butylphenol)；2,2'-thiobis[4-tert-butylphenol]；4,4'-di-tert-butyl-2,2'-sulfanediyl-di-phenol；Di(2-hydroxy-5-tert-butylphenyl) sulfide；4-tert-butyl-2-(5-tert-butyl-2-hydroxyphenyl)sulfanylphenol
• CAS: 3273-24-3
• 化学式: C₂₀H₂₆O₂S
• 分子量: 330.491
• InChiKey: KERJVHXRZDUVKQ-UHFFFAOYSA-N

物化性质

• 熔点：
  98-101 °C
• 沸点：
  441.9±45.0 °C(Predicted)
• 密度：
  1.14±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.6
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  65.8
• 氢给体数：
  2
• 氢受体数：
  3

安全信息

• 海关编码：
  2930909090

反应信息

• 作为反应物：
  描述：

  2,2'-thiobis<4-t-butylphenol> 在 1,2,3,4,5,6,7,8-八硫杂环辛烷 、 sodium hydroxide 作用下， 以 二苯醚 为溶剂， 反应 12.0h， 以83%的产率得到4-叔丁基硫杂杯[4]芳烃
  参考文献：
  名称：

  的合成对-叔-butylthiacalix [ Ñ ]芳烃（ñ从的硫桥无环二聚体= 4，图6和8）对叔丁基苯酚

  摘要：

  通过在碱的存在下使对-叔丁基苯酚1与元素硫反应来合成对-叔丁基硫杂杯[ n ]芳烃TCnA s（n = 4和6）的一步法被有利地替换为两个首先制备硫桥连的线性二聚体1的步骤，将其用作与硫进行环缩合的起始原料，以大大提高TC4A（83％）和TC6A（5.3％）的产率。本二聚体方法允许首次分离出可观量（4.3％）的TC8A。

  DOI：

  10.1016/s0040-4039(02)00214-9
• 作为产物：
  描述：

  4-叔丁基苯酚 在 二氯化硫 作用下， 以 二氯甲烷 为溶剂， 反应 1.33h， 以91%的产率得到2,2'-thiobis<4-t-butylphenol>
  参考文献：
  名称：

  2,14-Dithiacalix [4] arene及其homooxa类似物：构象行为的合成和动态NMR研究。

  摘要：

  报道了具有交替桥（-CH 2-和-S-）的2，14-二硫杂杯[4]芳烃的简单且可扩展的合成。的适当选择的双酚制原料构建块可提供不仅具有三个不同的桥接单元的标题化合物（58％），但也还没有报告homooxa类似物（-CH 2 - ， - S-和-CH 2 -O-CH 2 - ）中分子。这些系统表现出有趣的构象行为，从而允许使用动态NMR技术研究圆形氢键阵列的触发器运动。

  DOI：

  10.1039/c5cc00819k

文献信息

• Method for the preparation of aromatic chloroformates
  申请人：Davis Charles Gary

  公开号：US20060293535A1

  公开（公告）日：2006-12-28

  A method for preparing an aromatic chloroformate comprising, introducing a mixture of at least one aromatic hydroxyl compound, phosgene, at least one solvent, and at least one organic base into a flow reactor to obtain a unidirectionally flowing reaction mixture. The unidirectionally flowing reaction mixture is maintained at a temperature between about 0° C. and about 60° C. to produce a single product stream comprising an aromatic chloroformate.

  一种制备芳香氯甲酸酯的方法包括，将至少一种芳香羟基化合物、光气、至少一种溶剂和至少一种有机碱的混合物引入流动反应器中，以获得单向流动的反应混合物。将单向流动的反应混合物保持在约0°C至约60°C的温度下，以产生包含芳香氯甲酸酯的单一产物流。
• Method for the preparation of aliphatic chloroformates
  申请人：Davis Charles Gary

  公开号：US20060084822A1

  公开（公告）日：2006-04-20

  A method for preparing an aliphatic chloroformate comprising, introducing a mixture of at least one aliphatic hydroxyl compound, phosgene, at least one solvent, and optionally at least one organic base into a flow reactor to obtain a unidirectional flowing reaction mixture. The at least one aliphatic hydroxyl compound comprises at least one aliphatic hydroxyl group. The unidirectional flowing reaction mixture is maintained at a temperature between about 0° C. and about 60° C. to produce a single product stream comprising an aliphatic chloroformate.

  制备脂肪基氯甲酸酯的方法包括，将至少一种脂肪基羟基化合物、光气、至少一种溶剂以及可选的至少一种有机碱的混合物引入流动反应器中，以获得单向流动的反应混合物。至少一种脂肪基羟基化合物包括至少一种脂肪基羟基。将单向流动的反应混合物保持在约0°C至约60°C的温度下，以产生包含脂肪基氯甲酸酯的单一产物流。
• FLUORESCENT BRIGHTENERS, METHODS OF PREPARATION THEREOF, FLUORESCENT BRIGHTENER COMPOSITIONS, AND METHODS OF PREPARATION AND USES THEREOF
  申请人：Naik Shantaram Narayan

  公开号：US20110065843A1

  公开（公告）日：2011-03-17

  A compound of Formula (I) wherein R 1 , R 2 , and R 3 are independently at each occurrence hydrogen, a halogen, a cyano functionality, a C 1 -C 20 aliphatic functionality, a C 3 -C 10 cycloaliphatic functionality or a C 3 -C 20 aromatic functionality, with the proviso that R 2 and R 3 are not hydrogen when R 1 is a methyl or hydrogen; R 4 and R 5 are independently at each occurrence hydrogen, a halogen, a cyano functionality, a C 1 -C 20 aliphatic functionality, a C 3 -C 10 cycloaliphatic functionality or a C 3 -C 10 aromatic functionality; R 7 and R 8 are independently at each occurrence, a halogen, a cyano functionality, a C 1 -C 20 aliphatic functionality, a C 3 -C 10 cycloaliphatic functionality or a C 3 -C 10 aromatic functionality; R 6 is a C 2 -C 20 aliphatic functionality, a C 3 -C 10 cycloaliphatic functionality or a C 3 -C 20 aromatic functionality; and “n” and “m” are each independently integers having a value of 0 to 3.

  化合物的化学式（I），其中R1、R2和R3在每次出现时独立地为氢、卤素、氰基、C1-C20脂肪基、C3-C10环脂肪基或C3-C20芳香基，但R1为甲基或氢时，R2和R3不为氢；R4和R5在每次出现时独立地为氢、卤素、氰基、C1-C20脂肪基、C3-C10环脂肪基或C3-C10芳香基；R7和R8在每次出现时独立地为卤素、氰基、C1-C20脂肪基、C3-C10环脂肪基或C3-C10芳香基；R6为C2-C20脂肪基、C3-C10环脂肪基或C3-C20芳香基；“n”和“m”分别独立地为0至3的整数。
• Fluorescent brighteners, methods of preparation thereof, fluorescent brightener compositions, and methods of preparation and uses thereof
  申请人：Naik Narayan Shantaram

  公开号：US20070117887A1

  公开（公告）日：2007-05-24

  A compound of Formula (I) wherein R 1 , R 2 , and R 3 are independently at each occurrence hydrogen, a halogen, a cyano functionality, a C 1 -C 20 aliphatic functionality, a C 3 -C 10 cycloaliphatic functionality or a C 3 -C 20 aromatic functionality, with the proviso that R 2 and R 3 are not hydrogen when R 1 is a methyl or hydrogen; R 4 and R 5 are independently at each occurrence hydrogen, a halogen, a cyano functionality, a C 1 -C 20 aliphatic functionality, a C 3 -C 10 cycloaliphatic functionality or a C 3 -C 10 aromatic functionality; R 7 and R 8 are independently at each occurrence, a halogen, a cyano functionality, a C 1 -C 20 aliphatic functionality, a C 3 -C 10 cycloaliphatic functionality or a C 3 -C 10 aromatic functionality; R 6 is a C 2 -C 20 aliphatic functionality, a C 3 -C 10 cycloaliphatic functionality or a C 3 -C 20 aromatic functionality; and “n” and “m” are each independently integers having a value of 0 to 3.

  式(I)的化合物，其中R1、R2和R3在每次出现时独立地为氢、卤素、氰基、C1-C20脂肪基、C3-C10环脂肪基或C3-C20芳香基，但R1为甲基或氢时，R2和R3不为氢；R4和R5在每次出现时独立地为氢、卤素、氰基、C1-C20脂肪基、C3-C10环脂肪基或C3-C10芳香基；R7和R8在每次出现时独立地为卤素、氰基、C1-C20脂肪基、C3-C10环脂肪基或C3-C10芳香基；R6为C2-C20脂肪基、C3-C10环脂肪基或C3-C20芳香基；“n”和“m”分别独立地为0至3的整数。
• Synthesis and Inclusion Properties of Sulfur-Bridged Analogs of Acyclic Phenol-Formaldehyde Oligomers
  作者：Yoshihiro Ohba、Kazuhiko Moriya、Tyo Sone

  DOI：10.1246/bcsj.64.576

  日期：1991.2

  methylene bridges of acyclic p-methyl- and p-t-butylphenol–formaldehyde tetramers were replaced by sulfur bridge(s) was synthesized. It was found that though the sulfur-bridged tetramers formed crystalline host-guest complexes with a variety of organic compounds, they were different from the parent tetramers regarding their inclusion behavior. The number and position of the sulfur bridge(s), as well

  合成了一系列化合物，其中无环对甲基-和对-丁基苯酚-甲醛四聚体的部分或全部亚甲基桥被硫桥取代。发现虽然硫桥连四聚体与多种有机化合物形成结晶主客体复合物，但它们的包合行为与母体四聚体不同。硫桥的数量和位置，以及四聚体中苯酚的对位取代基，对包合性质有很大影响。硫桥连四聚体 (SSS-a,b) 与苯的复合物的热稳定性，根据它们的热解离速率估计，低于母体四聚体 (CCC-a,b) 的热稳定性。