(E)-5-(4-methoxystyryl)oxazole | 1276118-91-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: (E)-5-(4-methoxystyryl)oxazole
• 英文别名: E-5-(4-methoxystyryl)oxazole；5-[(E)-2-(4-methoxyphenyl)ethenyl]-1,3-oxazole
• CAS: 1276118-91-2
• 化学式: C₁₂H₁₁NO₂
• 分子量: 201.225
• InChiKey: OSSSKNGHMQPELW-QPJJXVBHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  35.3
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  (E)-5-(4-methoxystyryl)oxazole 在 碘 作用下， 以 苯 为溶剂， 反应 20.0h， 以62%的产率得到8-methoxynaphtho[1,2-d]oxazole
  参考文献：
  名称：

  Photochemical Approach to Naphthoxazoles and Fused Heterobenzoxazoles from 5-(Phenyl/heteroarylethenyl)oxazoles

  摘要：

  A new synthetic approach is presented for the synthesis of naphthoxazoles and fused heterobenzoxazoles. The starting 5-(aryl/furyl/thienyl/pyridyl ethenyl)oxazoles are prepared from the corresponding alpha,beta-unsaturated aldehydes using Van Leusen reagent in very good yields and are transformed into naphthoxazoles and fused heterobenzoxazoles on irradiation under aerobic conditions and in the presence of iodine.

  DOI：

  10.1021/jo1025942
• 作为产物：
  描述：

  Z-5-(4-methoxystyryl)oxazole 以 环己烷 为溶剂， 生成 (E)-5-(4-methoxystyryl)oxazole
  参考文献：
  名称：

  Photoisomerization and Photocyclization of 5-Styryloxazole

  摘要：

  This paper describes the competition of the relaxation processes (fluorescence, isomerization and cyclization) of 5-styryloxazole in the first excited singlet state. The study is carried out under mild conditions and in the first stage of irradiation to compare the photobehaviour with that reported in a previous work on preparative scale. The quantum yields of the radiative and reactive deactivation are compared with those of the analogous compounds containing pentatomic heteroaryl groups.

  DOI：

  10.5562/cca2443

文献信息

• Photochemical Approach to Naphthoxazoles and Fused Heterobenzoxazoles from 5-(Phenyl/heteroarylethenyl)oxazoles
  作者：Ivana Šagud、Fabio Faraguna、Željko Marinić、Marija Šindler-Kulyk

  DOI：10.1021/jo1025942

  日期：2011.4.15

  A new synthetic approach is presented for the synthesis of naphthoxazoles and fused heterobenzoxazoles. The starting 5-(aryl/furyl/thienyl/pyridyl ethenyl)oxazoles are prepared from the corresponding alpha,beta-unsaturated aldehydes using Van Leusen reagent in very good yields and are transformed into naphthoxazoles and fused heterobenzoxazoles on irradiation under aerobic conditions and in the presence of iodine.
• Photoisomerization and Photocyclization of 5-Styryloxazole
  作者：Ivana Šagud、Marija Šindler-Kulyk、Anna Spalletti、Ugo Mazzucato

  DOI：10.5562/cca2443

  日期：——

  This paper describes the competition of the relaxation processes (fluorescence, isomerization and cyclization) of 5-styryloxazole in the first excited singlet state. The study is carried out under mild conditions and in the first stage of irradiation to compare the photobehaviour with that reported in a previous work on preparative scale. The quantum yields of the radiative and reactive deactivation are compared with those of the analogous compounds containing pentatomic heteroaryl groups.