2,5-双(氯甲基)呋喃 | 6214-02-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 杂芳族化合物
• 中文名称: 2,5-双(氯甲基)呋喃
• 英文名称: 2,5-bis-chloromethyl-furan
• 英文别名: Furan, 2,5-bis(chloromethyl)-；2,5-bis(chloromethyl)furan
• CAS: 6214-02-4
• 化学式: C₆H₆Cl₂O
• mdl: MFCD15144104
• 分子量: 165.019
• InChiKey: SMUHBYFLABISAB-UHFFFAOYSA-N

物化性质

• 熔点：
  27-28 °C
• 沸点：
  80-83 °C(Press: 4 Torr)
• 密度：
  1.303 g/cm3(Temp: 25 °C)

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.333
• 拓扑面积：
  13.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2,5-双(氯甲基)呋喃 在 盐酸 、 氢氧化钾 、 sodium hydroxide 、 四丁基碘化铵 、 一水合肼 作用下， 以 乙二醇 为溶剂， 反应 3.58h， 生成 <3>metacyclo<3>(2,5)furanophane
  参考文献：
  名称：

  Synthesis of [3.3]heterophanes containing the pyridine, furan, and thiophene rings by the TosMIC method

  摘要：

  DOI：

  10.1021/jo00359a033
• 作为产物：
  描述：

  2,5-呋喃二甲醇 在 氯化亚砜 作用下， 以 吡啶 、 氯仿 为溶剂， 生成 2,5-双(氯甲基)呋喃
  参考文献：
  名称：

  简便地制备高分子量，高导电性的聚（2,5-呋喃亚乙烯基）

  摘要：

  易于通过水溶性前体聚合物制备聚（2,5-呋喃亚乙烯基）（PFV）的高分子量独立膜，可电化学可逆地施主和受主掺杂，在受主掺杂时电导率高达36 S / cm 。

  DOI：

  10.1039/c39870001113

文献信息

• (POP)Rh pincer hydride complexes: unusual reactivity and selectivity in oxidative addition and olefin insertion reactions
  作者：Michael C. Haibach、David Y. Wang、Thomas J. Emge、Karsten Krogh-Jespersen、Alan S. Goldman

  DOI：10.1039/c3sc50380a

  日期：——

  addition of H2 to a highly reactive three-coordinate species. Ethylene is hydrogenated by (tBuxanPOP)Rh(H)2+ at 25 °C, but propylene is not, even at elevated temperatures. Ethylene undergoes insertion into the Rh–H bond of (tBuxanPOP)RhH; this reaction is reversible, allowing for an experimental determination of the equilibrium constant for this hydrometalation. The less bulky iPrxanPOP ligand affords a

  我们对铑络合物配笨重的合成和反应性报告，中性配位体钳形具有“POP”协调基序，吨卜xanPOP，的iPr xanPOP，和吨卜furPOP（吨卜xanPOP = 4,5-双（二-叔-丁基膦基）-9,9-二甲基-9 H - the吨; iPr xanPOP = 4,5-双（二异丙基膦基）-9,9-二甲基-9 H - the吨; t Bu furPOP = 2,5-bis（（di-叔-丁基膦基）甲基）呋喃）。通常，这项工作中描述的（POP）Rh复合物比其（PNP）Rh和（PCP）Rh类似物具有更高的反应活性，从而可以在相对温和的条件下生成数个新物种。因此，单体（POP）RhCl络合物氧化加成H 2形成（POP）Rh（H）2 Cl，由其配位的不饱和氢化物络合物（POP）Rh（H）2 +和（t Bu xanPOP）Rh（H）可以获得。在新的配体t Bu furPOP的情况下，与H 2的反应的主要动
• Chiral Heterocyclic Ligands. VIII. Syntheses and Complexes of New Chelating Ligands Derived From Camphor
  作者：AA Watson、DA House、PJ Steel

  DOI：10.1071/ch9951549

  日期：——

  The syntheses of 23 new chelating ligands are described. Most of these ligands are derived from the chiral pyrazole (1) which has been linked to a variety of heterocycles , namely pyridine, pyrimidine, pyridazine, isoxazole , benzimidazole, thiophen and furan. In certain cases the parent achiral analogues have also been prepared. Preliminary studies of the coordination chemistry of these ligands with selected transition metals have been carried out. The X-ray crystal structures of palladium complexes of isoxazole- and thiophen-containing ligands have also been determined.

  本文介绍了 23 种新型螯合配体的合成。这些配体大多来自手性吡唑（1），而吡唑（1）已与多种杂环连接，即吡啶、嘧啶、哒嗪、异噁唑、苯并咪唑、噻吩和呋喃。在某些情况下，还制备出了母体非手性类似物。对这些配体与某些过渡金属的配位化学进行了初步研究。此外，还测定了含异噁唑和噻吩配体的钯配合物的 X 射线晶体结构。
• TETRAHYDROFURAN DERIVATIVES AND USE THEREOF AS PLASTICIZERS
  申请人：BASF SE

  公开号：US20160075671A1

  公开（公告）日：2016-03-17

  The invention relates to tetrahydrofuran derivatives of general formula (I), wherein X stands for *—(C═O)—O—, *—(CH2)n-O—, or *—(CH2)n-O—(C═O)—, wherein * represents the point of bonding to the tetrahydrofuran ring and n has the value 0, 1, or 2; and R1 and R2 are selected independently of each other from among C4-C5 alkyl and C5-C6 cycloalkyl, wherein the cycloalkyl groups are unsubstituted or can be substituted by at least one C1-C10 alkyl group, a plasticizer composition that contains said tetrahydrofuran derivatives, molding masses that contain a thermoplastic polymer or an elastomer and such a tetrahydrofuran derivative. The invention further relates to a method for producing said tetrahydrofuran derivatives, and to the use of said tetrahydrofuran derivatives

  该发明涉及一般式(I)的四氢呋喃衍生物，其中X代表*—(C═O)—O—、*—(CH2)n-O—或*—( )n-O—(C═O)—，其中*代表与四氢呋喃环的连接点，n的值为0、1或2；R1和R2分别从C4-C5烷基和C5-C6环烷基中独立选择，其中环烷基可以是未取代的或可以被至少一个C1-C10烷基基团取代，含有所述四氢呋喃衍生物的增塑剂组合物，含有热塑性聚合物或弹性体以及该四氢呋喃衍生物的成型物料。该发明还涉及制备所述四氢呋喃衍生物的方法，以及使用所述四氢呋喃衍生物。
• Synthesis, antimicrobial activity, and ion transportation investigation of four new [1 + 1] condensed furan and thiophene‐based cycloheterophane amides
  作者：Betül Erkuş、Hafize Özcan、Ömer Zaim

  DOI：10.1002/jhet.3922

  日期：2020.4

  Four new macrocyclic compounds with thiophene (L1 and L2) and furan (L3 and L4) rings were synthesized and characterized by IR, 1H NMR, 13C NMR, and Q‐TOF spectral data. Macrocyclic amides (L1, L2, L3, and L4) were tested for ion transportation with Na+ and K+ ions, and also, antimicrobial activities were investigated against the Gram‐negative Escherichia coli ATCC 25922, Gram‐positive Staphylococcus

  合成了四种具有噻吩（L1和L2）和呋喃（L3和L4）环的大环化合物，并通过IR，1 H NMR，13 C NMR和Q-TOF光谱数据进行了表征。测试了大环酰胺（L1，L2，L3和L4）与Na +和K +离子的离子迁移，还研究了其对革兰氏阴性大肠杆菌ATCC 25922，革兰氏阳性金黄色葡萄球菌ATCC 25923，革兰氏阴性李斯特菌ATCC 19115，革兰氏阴性鼠伤寒沙门氏菌ATCC 14028，蜡状芽孢杆菌细菌和白色念珠菌ATCC 10231，用于所有酰胺类。
• Synthesis and characterisation of some 1,4,8,11,15,18,22,25-octa(alkoxymethyl)phthalocyanines; a new series of discotic liquid crystals
  作者：Andrew N. Cammidge、Michael J. Cook、Kenneth J. Harrison、Neil B. McKeown

  DOI：10.1039/p19910003053

  日期：——

  converted into the corresponding phthalocyanines. Zn(II) and Cu(II) derivatives of 1,4,8,11,15,18,22,25-octa(heptyloxymethyl)phthalocyanine were also prepared. Examples of the macrocycles were characterised using 1H NMR spectrometry and optical spectroscopy. Those bearing straight chains aggregate in solutions of chloroform and toluene. The octa(butoxymethyl)phthalocyanine and its longer chain homologues

  通过2，5-双（烷氧基甲基）呋喃与富马腈的Diels-Alder反应制备的一系列3，6-双（烷氧基甲基）邻苯二甲腈已转化为相应的酞菁。还制备了1,4,8,11,15,18,22,25-八（庚氧基甲基）酞菁的Zn（II）和Cu（II）衍生物。大环的实例使用1 H NMR光谱法和光学光谱法表征。那些带有直链的物质聚集在氯仿和甲苯的溶液中。八（丁氧基甲基）酞菁及其较长链的同系物呈现盘状液晶相。含有支链侧链的化合物在室温下为液晶。