2-[(2,4-二甲基苯氧基)甲基]环氧乙烷 | 20217-04-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 中文名称: 2-[(2,4-二甲基苯氧基)甲基]环氧乙烷
• 英文名称: 2-((2,4-dimethylphenoxy)methyl)oxirane
• 英文别名: 2-(2,4-dimethylphenoxy)methyl oxirane；1-(2,4-dimethylphenoxy)-2,3-epoxypropane；2-[(2,4-Dimethylphenoxy)methyl]oxirane
• CAS: 20217-04-3
• 化学式: C₁₁H₁₄O₂
• mdl: MFCD08691080
• 分子量: 178.231
• InChiKey: AYVQIRLANZOASX-UHFFFAOYSA-N

物化性质

• 沸点：
  271.5±20.0 °C(Predicted)
• 密度：
  1.071±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.454
• 拓扑面积：
  21.8
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2910900090

反应信息

• 作为反应物：
  描述：

  2-[(2,4-二甲基苯氧基)甲基]环氧乙烷 在 氢氧化钾 、 正丁基锂 作用下， 以 四氢呋喃 、 乙醚 、 乙醇 为溶剂， 反应 14.5h， 生成 3-(2,4-dimethylphenyloxymethyl)-3,4-dihydroisocoumarin
  参考文献：
  名称：

  Brahmbhatt; Pandya, Urvish R., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2003, vol. 42, # 9, p. 2100 - 2103

  摘要：

  DOI：
• 作为产物：
  描述：

  1-Chloro-3-(2,4-dimethyl-phenoxy)-propan-2-ol 在 sodium hydroxide 作用下， 以 四氢呋喃 为溶剂， 反应 0.67h， 生成 2-[(2,4-二甲基苯氧基)甲基]环氧乙烷
  参考文献：
  名称：

  Antihypertensive indole derivatives of phenoxypropanolamines with .beta.-adrenergic receptor antagonist and vasodilating activity

  摘要：

  A series of 25 aryloxypropanolamines containing the 3-indolyl-tert-butyl [i.e., 1,1-dimethyl-2-(1H-indol-3-yl)ethyl] or substituted 3-indolyl-tert-butyl moiety as the N substituent is reported. These compounds have been tested for antihypertensive activity in spontaneously hypertensive rats (SHR), beta-adrenergic receptor antagonist action in conscious normotensive rats, vasodilating activity in ganglion-blocked rats with blood pressure maintained by angiotensin II infusion, and for intrinsic sympathomimetic action (ISA) in reserpinized rats. Some of the compounds exhibit antihypertensive activity in combination with beta adrenergic receptor antagonist and vasodilating action. The structure--activity relationships in these tests are discussed.

  DOI：

  10.1021/jm00177a015

文献信息

• ALKALI-DEVELOPABLE PHOTOSENSITIVE RESIN COMPOSITION AND BETA-DIKETONE COMPOUND
  申请人：Yamada Takashi

  公开号：US20100129753A1

  公开（公告）日：2010-05-27

  An alkali developable photosensitive resin composition contains (J) a photopolymerizable unsaturated compound having a structure resulting from the addition reaction of (B) a compound having a β-diketone moiety or a compound having a β-ketoester group to the (meth)acryloyl group of (A) a compound having at least two (meth)acryloyl groups and a hydroxyl group and subsequent esterification of the hydroxyl group of the resulting addition product with (C) a polybasic acid anhydride. The compound having a β-diketone moiety is preferably a novel β-diketone compound represented by general formula (I): wherein R 1 is a C1-C20 alkyl group; R 2 represents R 11 , OR 11 , COR 11 , SR 11 , CONR 12 R 13 , or CN; R 11 , R 12 , and R 13 are each hydrogen, a C1-C20 alkyl group, etc.; a is 0 to 3; and b is 0 to 4.

  一种可由碱显影的光敏树脂组合物，含有（J）一种光聚合不饱和化合物，该化合物的结构是由（B）含β-二酮基团或含β-酮酯基团的化合物与（A）含至少两个(甲基)丙烯酰基团和一个羟基的化合物中的(甲基)丙烯酰基团发生加成反应，并随后将所得加成产物的羟基与（C）多元酸酐进行酯化反应得到的。含β-二酮基团的化合物最好是表示为通用公式（I）的一种新型β-二酮化合物：其中R1是C1-C20烷基团；R2代表R11、OR11、COR11、SR11、CONR12R13或CN；R11、R12和R13分别是氢、C1-C20烷基团等；a是0到3；b是0到4。
• NBS/DMSO-mediated synthesis of (2,3-dihydrobenzo[<i>b</i>][1,4]oxathiin-3-yl)methanols from aryloxymethylthiiranes
  作者：Jun Dong、Jiaxi Xu

  DOI：10.1039/c8nj01117f

  日期：——

  4]oxathiin-3-yl)methanols were synthesized via reactions of aryloxymethylthiiranes and N-bromosuccinimide (NBS) in DMSO under microwave irradiation. The reaction mechanism was proposed as an intramolecular aromatic electrophilic substitution of 1-bromo-2-(aryloxymethyl)thiiran-1-iums, generated from aryloxymethylthiiranes and NBS, and the subsequent DMSO nucleophilic ring opening reaction of thiiran-1-iums followed by

  通过芳氧基甲基硫烷和N-溴琥珀酰亚胺（NBS）在DMSO下微波辐射反应合成了（2,3-二氢苯并[ b ] [1,4]氧杂嘧啶-3-基）甲醇。该反应机理被认为是由芳氧基甲基噻喃和NBS生成的1-溴-2-（芳氧基甲基）噻喃-1-鎓的分子内芳族亲电取代，以及随后的噻吩-1-鎓的DMSO亲核开环反应，随后是排水量。当前的方法提供了一种直接和简单的策略，可以从容易获得的芳氧基甲基噻喃有效地制备（2,3-二氢苯并[ b ] [1,4]氧杂蒽-3-基）甲醇。
• NOVEL COMPOUND, DYE AND COLORED PHOTOSENSITIVE COMPOSITION
  申请人：Maeda Yosuke

  公开号：US20130296455A1

  公开（公告）日：2013-11-07

  Disclosed are a dye that is excellent in solubility and heat-resistance, and a novel compound that is suitable for the dye, and specifically provides a yellow dye having a maximum absorption wavelength in the region of 420 to 470 nm. Also disclosed are a colored (alkali-developable) photosensitive composition and an optical filter using the dye, and specifically provides a color filter that does not decrease luminance and thus is preferable for an image display device such as a liquid crystal display panel. Specifically, disclosed are a novel compound represented by the following general formula (1), a dye using the compound, and a colored (alkali-developable) photosensitive composition and a color filter. The content of the above-mentioned general formula (1) is as described in the description.

  揭示了一种在溶解性和耐热性方面表现优异的染料，以及一种适用于该染料的新化合物，具体提供了在420至470纳米波长区域具有最大吸收波长的黄色染料。还公开了一种着色（碱可显影）光敏组合物和使用该染料的光学滤光片，具体提供了一种不降低亮度且适用于像液晶显示面板等图像显示设备的彩色滤光片。具体地，公开了以下通用公式（1）表示的新化合物，使用该化合物的染料，以及着色（碱可显影）光敏组合物和彩色滤光片。上述通用公式（1）的内容如描述中所述。
• OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING SAID COMPOUND
  申请人：ADEKA CORPORATION

  公开号：US20170166575A1

  公开（公告）日：2017-06-15

  The present invention provides oxime ester compounds represented by general formula (I), a photopolymerization initiator using said compound, and a photosensitive composition, alkali-developable photosensitive resin composition, and colored alkali-developable photosensitive resin composition containing same, and cured products thereof. The compounds of the present invention have excellent stability and low sublimability, and are useful as highly sensitive photopolymerization initiators that are activated by efficiently absorbing near ultraviolet light of 365 nm, etc. (I) (See the Specification for the definitions of R 1 -R 8 in the formula. n represents 0 or 1.)

  本发明提供了一种由通用式（I）表示的肟酯化合物，使用该化合物的光聚合引发剂，以及包含相同化合物的光敏组合物、可碱开发的光敏树脂组合物和着色的可碱开发的光敏树脂组合物及其固化产品。本发明的化合物具有优异的稳定性和低升华性，并且可作为高灵敏度的光聚合引发剂，通过高效吸收365纳米等近紫外光激活。（I）（有关R1-R8在式中的定义，请参见说明书。n代表0或1。）
• NOVEL COMPOUND HAVING alpha-CYANOACRYLATE STRUCTURE, DYE, AND COLORED PHOTOSENSITIVE COMPOSITION
  申请人：Maeda Yosuke

  公开号：US20140005292A1

  公开（公告）日：2014-01-02

  A compound represented by the following general formula (1). In the formula, A represents a benzene ring, a naphthalene ring and the like, wherein these rings may be substituted with a halogen atom and the like, R 1 represents a hydrogen atom and the like, R 2 represents a C 1-35 hydrocarbon group having or not having at least one group selected from an epoxy group, 4-vinylphenyl group and a (meth)acryloyloxy group, or a hydrogen atom, wherein at least one of R 2 with n occurrences is a C 3-35 hydrocarbon group having at least one group selected from an epoxy group, a 4-vinylphenyl group and a (meth)acryloyloxy group, n represents an integer of 1 to 6, and X represents a nitrogen atom, an oxygen atom, a sulfur atom, a phosphorus atom, or an n-valent organic group having 35 or less carbon atoms.

  以下为通式（1）所代表的化合物。其中，A代表苯环、萘环等，这些环可能被卤素等取代，R1代表氢原子等，R2代表具有或不具有环氧基团、4-乙烯基苯基团和（甲基）丙烯酰氧基团中至少一种基团的C1-35碳氢基团或氢原子，其中R2中至少有一个出现n次的基团是具有至少一种环氧基团、4-乙烯基苯基团和（甲基）丙烯酰氧基团中的一种的C3-35碳氢基团，n表示1到6的整数，X表示氮原子、氧原子、硫原子、磷原子或具有35个或更少碳原子的n价有机基团。