6-bromohexanoic acid Na-salt | 50530-06-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 6-bromohexanoic acid Na-salt
• 英文别名: 6-bromohexanoic acid sodium salt；6-bromohexanoate sodium；Sodium 6-bromohexanoate；sodium;6-bromohexanoate
• CAS: 50530-06-8
• 化学式: C₆H₁₀BrO₂*Na
• 分子量: 217.038
• InChiKey: UWHWTUHOJMSSBX-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -2.3
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  40.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  6-bromohexanoic acid Na-salt 在 9-borabicyclo[3.3.1]nonane dimer 作用下， 以 四氢呋喃 为溶剂， 反应 1.0h， 以78%的产率得到6-溴己醛
  参考文献：
  名称：

  Cha, Jin Soon; Oh, Se Yeon; Lee, Kwang Woo, Heterocycles, 1988, vol. 27, # 7, p. 1595 - 1598

  摘要：

  DOI：
• 作为产物：
  描述：

  6-溴己酸 、 sodium 生成 6-bromohexanoic acid Na-salt
  参考文献：
  名称：

  FUJISAWA, TAMOTSU;IIDA, SACHIO;UEHARA, HIROSHI;SATO, TOSHIO, CHEM. LETT., 1983, N 8, 1267-1270

  摘要：

  DOI：

文献信息

• SIMPLE AND CHEMOSELECTIVE SYNTHESIS OF KETONES FROM CARBOXYLIC ACIDS AND GRIGNARD REAGENTS USING DICHLOROTRIPHENYLPHOSPHORANE
  作者：Tamotsu Fujisawa、Sachio Iida、Hiroshi Uehara、Toshio Sato

  DOI：10.1246/cl.1983.1267

  日期：1983.8.5

  Dichlorotriphenylphosphorane was found to be a good condensation reagent for synthesis of ketones from carboxylic acids and Grignard reagents under mild conditions. Synthetic utility of the present method is demonstrated by the chemoselective reaction of carboxylic acids possessing such a functional group as halogen, cyano, or carbonyl.

  发现二氯三苯基膦是在温和条件下由羧酸和格氏试剂合成酮的良好缩合试剂。本方法的合成效用通过具有卤素、氰基或羰基等官能团的羧酸的化学选择性反应来证明。
• Carboxybetaine and sulfobetaine and detergent composition and cosmetic containing the same
  申请人：KAO CORPORATION

  公开号：EP0649834A1

  公开（公告）日：1995-04-26

  Novel carboxybetaines and sulfobetaines are disclosed. Processes of the production of the carboxybetaines and sulfobetaines, as well as detergent compositions and cosmetics containing these compounds are also disclosed. The carboxybetaines and sulfobetaines of the present invention show excellent moisture keeping effect which provides the skin and hair with moist feeling for a prolonged period of time.

  本发明揭示了新型的羧基丙氨酸盐和磺基丙氨酸盐。本发明还揭示了制备羧基丙氨酸盐和磺基丙氨酸盐的方法，以及包含这些化合物的洗涤剂组合物和化妆品。本发明中的羧基丙氨酸盐和磺基丙氨酸盐表现出卓越的保湿效果，为皮肤和头发提供长时间的湿润感。
• Thermographic materials processable at lower temperatures
  申请人：Maskasky E. Joe

  公开号：US20060019205A1

  公开（公告）日：2006-01-26

  Direct thermographic materials can be imaged at lower temperatures. These materials include a non-photosensitive, non-halogen-containing organic silver salt and a reducing agent for silver ions. The materials also contain a halogen-containing compound that has at least 2 carbon atoms and is capable of releasing its halogen to form silver halide when heated to a temperature between 60 and 141° C. in the presence of source of silver.

  直接热成像材料可以在较低温度下成像。这些材料包括一种非光敏、不含卤素的有机银盐和一种还原银离子的还原剂。这些材料还包含一种含有至少2个碳原子的卤素化合物，在存在银源的情况下，在60到141°C的温度范围内加热时，能够释放其卤素以形成银卤化物。
• Thermally developable materials processable at lower temperatures
  申请人：Eastman Kodak Company

  公开号：US07153635B1

  公开（公告）日：2006-12-26

  Black-and-white direct thermographic materials and photothermographic materials can be processed or developed at lower temperatures because of the incorporation of a quaternary ammonium salt in an amount of at least 0.5 mol % based on total silver in the material.

  黑白直接热敏材料和光热材料可以在较低的温度下处理或开发，因为其中包含了至少0.5摩尔％的季铵盐，基于材料中的总银量。
• Photochemical three-component assembly of tri-substituted oxazoles through a carbenic phosphorus-nitrile hybrid ylide formation/trapping cascade
  作者：Xingchen Ye、Huaijin Pan、Yong Huang、Jiean Chen、Zhaofeng Wang

  DOI：10.1039/d4sc01355g

  日期：2024.5.1

  synthesis. We report a novel visible-light-induced three-component reaction for the construction of complex 2,4,5-trisubstituted oxazoles, which are valuable in medicinal chemistry, from simple and readily available iodonium-phosphonium hybrid ylides, carboxylic acids, and nitriles. This reaction features a carbenic phosphorus-nitrile hybrid ylide formation/trapping cascade, in which a photo-generated α-phosphonium

  在有机合成中，利用普遍存在的化学原料在一次转化中构建复杂的分子骨架非常有吸引力。我们报告了一种新型可见光诱导的三组分反应，用于从简单且容易获得的碘鎓杂化叶立德、羧酸和腈构建复杂的2,4,5-三取代恶唑，这在药物化学中很有价值。该反应以碳磷-腈混合叶立德形成/捕获级联为特征，其中光生α-鏻卡宾充当序列触发器。这种无催化剂和无添加剂的转化表现出高效率和广泛的底物范围，可合成多种恶唑。