4-(3,5-difluorophenoxy)-phenol | 95756-12-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(3,5-difluorophenoxy)-phenol
• 英文别名: p-(3,5-difluorophenoxy)phenol；4-(3,5-difluorophenoxy)phenol
• CAS: 95756-12-0
• 化学式: C₁₂H₈F₂O₂
• 分子量: 222.191
• InChiKey: JGWGGGZSRKCCLZ-UHFFFAOYSA-N

物化性质

• 沸点：
  301.6±42.0 °C(Predicted)
• 密度：
  1.331±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4-(3,5-difluorophenoxy)-phenol 生成 2-Methyl-2-[4-(3,5-difluorophenoxy)phenoxy]ethanol
  参考文献：
  名称：

  NISIDA, SUMIO;MATSUO, NORITAKA;XATA, KOSINOBU;KISIDA, XIROSI

  摘要：

  DOI：
• 作为产物：
  描述：

  4-(3,5-Difluorophenoxy)anisole 、 氢溴酸 、 在 乙醚 、 正己烷 、 水 、 magnesium sulfate 作用下， 以 溶剂黄146 为溶剂， 反应 8.0h， 以gave 4-(3,5-difluorophenoxy)phenol (20.27 g)的产率得到4-(3,5-difluorophenoxy)-phenol
  参考文献：
  名称：

  Certain-phenoxy-phenoxy-alkylene-oxy-pyrimidines or symmetrical

  摘要：

  一种含氮杂环化合物的化学式为：##STR1## 其中R.sub.1是以下任一基团之一：##STR2## （其中R.sub.7，R.sub.8，R.sub.9，R.sub.10，R.sub.11，R.sub.12，R.sub.13，R.sub.14，R.sub.15，R.sub.16和R.sub.17是相同或不同的氢原子，卤素原子，C.sub.1-C.sub.4烷基，C.sub.1-C.sub.4烷氧基，C.sub.1-C.sub.4烷硫基，三氟甲基或硝基；R.sub.18，R.sub.19，R.sub.20和R.sub.21是相同或不同的氢原子或甲基，k是0到1的整数，l是0到3的整数）；R.sub.2和R.sub.3是相同或不同的氢原子，卤素原子或甲基；R.sub.4是卤素原子或甲基；R.sub.5和R.sub.6是相同或不同的氢原子，卤素原子，C.sub.1-C.sub.4烷基，C.sub.1-C.sub.4烷氧基，C.sub.1-C.sub.4卤代烷基或C.sub.1-C.sub.4卤代烷氧基；X，Y和Z是相同或不同的氧原子，硫原子或亚甲基基团；m是0到4的整数；n是0到2的整数。该化合物可用作杀虫剂。

  公开号：

  US04879292A1

文献信息

• Use of ethyl 2-[4-(3,5-difluorophenoxy)phenoxy]ethylcarbamate for
  申请人：Ciba-Geigy Corporation

  公开号：US05082860A1

  公开（公告）日：1992-01-21

  Use of ethyl 2-[4-(3,5-difluorophenoxy)phenoxy]ethylcarbamate for controlling cicadas which damage rice crops.

  使用乙基2-[4-(3,5-二氟苯氧基)苯氧基]乙基氨基甲酸酯来控制危害稻田的蝉。
• Bisacylethylamines
  申请人：Ciba-Geigy Corporation

  公开号：US05166153A1

  公开（公告）日：1992-11-24

  Novel N-acylated 2-[4-(halophenoxy)-phenoxy]-ethylcarbamic acid esters of formula I ##STR1## wherein R.sub.1 is C.sub.1 -C.sub.8 alkyl or C.sub.3 -C.sub.5 alkenyl, R.sub.2 is C.sub.1 -C.sub.8 alkyl, C.sub.1 -C.sub.8 alkoxy, --CO--R.sub.7 or --NR.sub.8 R.sub.9, R.sub.3 and R.sub.4 independently of one another are hydrogen or methyl, R.sub.5 is chlorine or fluorine, R.sub.6 is either the same substituent as R.sub.5 or is hydrogen, R.sub.7 is C.sub.1 -C.sub.8 alkoxy or --NR.sub.10 R.sub.11, R.sub.8 is C.sub.1 -C.sub.4 alkyl, R.sub.9 is C.sub.1 -C.sub.4 alkyl or R.sub.8 and R.sub.9 together form a C.sub.4 -C.sub.6 alkylene chain which may be interrupted by oxygen, sulfur or --NCH.sub.3 --, R.sub.10 is hydrogen or C.sub.1 -C.sub.4 alkyl and R.sub.11 is hydrogen or C.sub.1 -C.sub.4 alkyl, benzyl, phenyl, or phenyl substituted by halogen or by methyl, or R.sub.10 and R.sub.11 together form a C.sub.4 -C.sub.6 alkylene chain which may be interrupted by oxygen, sulfur or --NCH.sub.3 --; their preparation, their use in pest control, and pesticidal compositions that contain those carbamic acid esters as active ingredient are disclosed.

  公式I中的新型N-酰化2-[4-(卤代)苯氧基]-苯氧基-乙酸酯，其中R.sub.1为C.sub.1-C.sub.8烷基或C.sub.3-C.sub.5烯基，R.sub.2为C.sub.1-C.sub.8烷基、C.sub.1-C.sub.8烷氧基、--CO--R.sub.7或--NR.sub.8 R.sub.9，R.sub.3和R.sub.4独立地为氢或甲基，R.sub.5为氯或氟，R.sub.6为与R.sub.5相同的取代基或氢，R.sub.7为C.sub.1-C.sub.8烷氧基或--NR.sub.10 R.sub.11，R.sub.8为C.sub.1-C.sub.4烷基，R.sub.9为C.sub.1-C.sub.4烷基或R.sub.8和R.sub.9共同形成的C.sub.4-C.sub.6烷基链，该链可以被氧、硫或--NCH.sub.3--所中断，R.sub.10为氢或C.sub.1-C.sub.4烷基，R.sub.11为氢或C.sub.1-C.sub.4烷基、苄基、苯基或被卤素或甲基取代的苯基，或R.sub.10和R.sub.11共同形成的C.sub.4-C.sub.6烷基链，该链可以被氧、硫或--NCH.sub.3--所中断；揭示了它们的制备方法、它们在害虫控制中的应用以及包含这些乙酸酯作为活性成分的杀虫剂组合物。
• Sulfenylated carbamic esters and their use in pesticides
  申请人：Ciba-Geigy Corporation

  公开号：US05192803A1

  公开（公告）日：1993-03-09

  Novel substituted 2-phenoxyphenoxyethylcarbamic esters of the formula I ##STR1## where R.sub.1 is C.sub.1 -C.sub.4 alkyl or C.sub.3 -C.sub.4 alkenyl, R.sub.2 is C.sub.1 -C.sub.4 alkyl or a radical of the formula ##STR2## --C(CH.sub.3).sub.2 --CN or --N(R.sub.9)--COO--C.sub.1 -C.sub.4 alkyl, R.sub.3 and R.sub.4 independently of one another are hydrogen or methyl, R.sub.5 is fluorine or chlorine, R.sub.6 is either identical to the substituents given in the case of R.sub.5 or is hydrogen, R.sub.7 and R.sub.8 independently of one another are hydrogen, halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy or nitro, R.sub.9 is C.sub.1 -C.sub.4 alkyl and n is zero, one or two, their preparation, their use in pest control, and pesticides containing these carbamic esters as active substance, are described. The preferred field of application is the control of pests on animals and plants, in partcular of eggs and larvae of phytophagous harmful insects and harmful mites.

  本发明涉及式I的新型取代的2-苯氧基苯氧基乙基氨基甲酸酯，其中R.sub.1是C.sub.1-C.sub.4烷基或C.sub.3-C.sub.4烯基，R.sub.2是C.sub.1-C.sub.4烷基或公式的基团：--C(CH.sub.3).sub.2--CN或--N(R.sub.9)--COO--C.sub.1-C.sub.4烷基，R.sub.3和R.sub.4分别独立地是氢或甲基，R.sub.5是氟或氯，R.sub.6要么与R.sub.5中给出的取代基相同，要么是氢，R.sub.7和R.sub.8独立地是氢，卤素，C.sub.1-C.sub.4烷基，C.sub.1-C.sub.4烷氧基或硝基，R.sub.9是C.sub.1-C.sub.4烷基，n为零，一或二。本发明还涉及这些氨基甲酸酯的制备方法，它们在害虫控制中的使用以及含有这些氨基甲酸酯作为活性成分的杀虫剂。首选的应用领域是在动植物上控制害虫，特别是植食性有害昆虫和有害螨的卵和幼虫。
• Pest control
  申请人：Ciba-Geigy Corporation

  公开号：US05077311A1

  公开（公告）日：1991-12-31

  Use of ethyl 2-[4-(3,5-difluorophenoxy)phenoxy]ethylcarbamate for controlling phytopathogenic insects of the families Aleyrodidae, Diaspididae, Coccidae, Tortricidae and Olethreutidae.

  乙基2-[4-(3,5-二氟苯氧基)苯氧基]乙基氨基甲酸酯用于控制伪叶蚜科、盾蚧科、蚧科、卷叶蛾科和蛾科的植物病原昆虫。
• Pyridine derivatives and their compositions for the control of insect
  申请人：——

  公开号：US05151428A1

  公开（公告）日：1992-09-29

  A pyridine derivative of the formula: ##STR1## wherein R.sup.1 is, the same or different, each a hydrogen atom, a halogen atom, a C.sub.1 -C.sub.4 alkyl group, a C.sub.1 -C.sub.4 haloalkyl group, a C.sub.1 -C.sub.3 alkoxy gorup, a C.sub.1 -C.sub.3 haloalkoxy group, a cyano group or a nitro group; R.sup.2 is, the same or different, each a hydrogen atom, a halogen atom or a methyl group; R.sup.3 is a halogen atom or a C.sub.1 -C.sub.3 alkyl group; R.sub.4 is a hydrogen atom or a C.sub.1 -C.sub.3 alkyl group; R.sup.5 is, the same or different, each a halogen atom, a C.sub.1 -C.sub.3 alkyl group, a C.sub.1 -C.sub.3 haloalkyl group, a C.sub.1 -C.sub.3 alkoxy group or a C.sub.1 -C.sub.3 haloalkoxy group; X is an oxygen atom, a sulfur atom, a carbonyl group, a sulfinyl group, a sulfonyl group, an imino group or a methylene group; Y is an oxygen atom or a sulfur atom; l is an integer of 1 to 5; m is an integer of 1 to 3; and n is an integer of 1 to 4, which is useful for control of insect pest.

  一种吡啶衍生物，其化学式为：##STR1## 其中R.sup.1是氢原子，卤素原子，C.sub.1-C.sub.4烷基，C.sub.1-C.sub.4卤代烷基，C.sub.1-C.sub.3烷氧基，C.sub.1-C.sub.3卤代烷氧基，氰基或硝基，可以相同或不同；R.sup.2是氢原子，卤素原子或甲基，可以相同或不同；R.sup.3是卤素原子或C.sub.1-C.sub.3烷基；R.sub.4是氢原子或C.sub.1-C.sub.3烷基；R.sup.5是氢原子，卤素原子，C.sub.1-C.sub.3烷基，C.sub.1-C.sub.3卤代烷基，C.sub.1-C.sub.3烷氧基或C.sub.1-C.sub.3卤代烷氧基，可以相同或不同；X是氧原子，硫原子，羰基，烷基硫醇基，烷基磺酰基，亚胺基或亚甲基基；Y是氧原子或硫原子；l是1到5的整数；m是1到3的整数；n是1到4的整数。该化合物对于控制昆虫害虫具有益处。