1,6-二吗啉基己烷 | 5815-60-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 中文名称: 1,6-二吗啉基己烷
• 英文名称: 1,6-di(morpholin-1-yl)hexane
• 英文别名: 1,6-dimorpholino-hexane；1,6-Dimorpholino-hexan；1,6-bismorpholinohexane；4-(6-Morpholin-4-ylhexyl)morpholine
• CAS: 5815-60-1
• 化学式: C₁₄H₂₈N₂O₂
• 分子量: 256.389
• InChiKey: CCKWMUGWAKTDIV-UHFFFAOYSA-N

物化性质

• 熔点：
  41 °C
• 沸点：
  190 °C(Press: 11 Torr)
• 密度：
  0.998±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  18
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  24.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1,6-二吗啉基己烷 在 氢氟酸 作用下， 以20%的产率得到perfluorodimorpholinohexane
  参考文献：
  名称：

  On the electrochemical fluorination of derivatives of morpholine and piperidine

  摘要：

  Electrochemical fluorination (ECF) of alpha,omega-dimorpholino- and dipiperidino-alkanes of different chain length (n = 1-6) and of morpholinocyclohexene gave the perfluoro derivatives in yields up to 45%. By ring contractions, fragmentations and rearrangements several side products were obtained. Conclusions on the mechanism of ECF, based on a sterical model, were drawn.

  DOI：

  10.1016/s0022-1139(00)80306-1
• 作为产物：
  描述：

  N-(3-氯丙基)吗啉 在 乙醇 、 镍 、 sodium amide 、 甲苯 作用下， 生成 1,6-二吗啉基己烷
  参考文献：
  名称：

  Hypotensive Agents. I. Acetylenic Diamines

  摘要：

  DOI：

  10.1021/ja01550a049

文献信息

• Ruthenium Catalyzed <i>N</i> -Alkylation of Cyclic Amines with Primary Alcohols
  作者：Risto Savela、Dieter Vogt、Reko Leino

  DOI：10.1002/ejoc.202000167

  日期：2020.5.29

  A robust alcohol amination protocol using common saturated cyclic amines and primary alcohols as starting material is described for synthesis of 29 compounds. The reactions are catalyzed by combination of dichloro(p ‐cymene)ruthenium(II) dimer precatalyst with triphenylphosphine ligand. The catalyst can be precipitated by addition of hexane or cold diethyl ether, followed by isolation of the product

  描述了使用常见的饱和环状胺和伯醇作为原料的鲁棒醇胺化方案，用于合成29种化合物。二氯对苯甲基钌（II）二聚体预催化剂与三苯基膦配体的结合可催化反应。可以通过加入己烷或冷二乙醚使催化剂沉淀，然后在大多数情况下无需色谱纯化即可分离出呈盐酸盐形式的产物。
• Dimeric N-Alkyl ammonium acetonitrile bleach activators
  申请人：The Clorox Company

  公开号：US05877315A1

  公开（公告）日：1999-03-02

  Bleaching compositions are provided that comprise two nitrile groups where each nitrile is bonded to a quaternary nitrogen through a methylene unit. The quaternary nitrogens are part of a saturated ring. This saturated ring contains from two to eight atoms in addition to the quaternary nitrogen. A source of active oxygen will react with the nitriles for bleaching applications.

  提供了含有两个腈基团的漂白组合物，其中每个腈基团通过一个亚甲基单元与一个季铵氮键合。这些季铵氮是饱和环的一部分。这个饱和环除了季铵氮外，还含有从两个到八个原子。活性氧的来源将与腈基团发生反应，用于漂白应用。
• N-alkyl ammonium acetonitrile bleach activators
  申请人：The Clorox Company

  公开号：US05739327A1

  公开（公告）日：1998-04-14

  Bleaching compositions are provided that comprise a nitrile containing compound that has the nitrile bonded to a quaternary nitrogen through a methylene unit (where one or both of the normal hydrogens can be substituted), and two of the quaternary nitrogen bonds are part of a saturated ring. This saturated ring contains from two to eight atoms in addition to the quaternary nitrogen. A source of active oxygen will react with the nitrile for bleaching applications. Particularly preferred nitrile containing compounds are N-alkyl morpholinium acetonitrile salts.

  提供了含有腈基化合物的漂白组合物，其中腈基通过亚甲基单元与季铵氮键合（正常氢原子中的一个或两个可以被取代），并且其中两个季铵氮键是饱和环的一部分。这个饱和环除了季铵氮外含有两到八个原子。活性氧的来源将与腈基反应，用于漂白应用。特别偏爱的含腈基化合物是N-烷基吗啉乙腈盐。
• POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS
  申请人：MERCK PATENT GMBH

  公开号：US20170121606A1

  公开（公告）日：2017-05-04

  The present invention relates to polymerizable compounds, to processes and intermediates for the preparation thereof, to liquid-crystal (LC) media comprising them, and to the use of the polymerizable compounds and LC media for optical, electro-optical and electronic purposes, in particular in LC displays, especially in LC displays of the polymer sustained alignment type, or a stabilizers in LC media and LC displays.

  本发明涉及可聚合化合物，以及用于制备它们的过程和中间体，包括含有它们的液晶（LC）介质，以及用于光学、电光和电子用途的可聚合化合物和LC介质的使用，特别是在LC显示器中，尤其是在聚合物维持对准型LC显示器中，或者作为LC介质和LC显示器中的稳定剂。
• POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS
  申请人：MERCK PATENT GMBH

  公开号：US20220127532A1

  公开（公告）日：2022-04-28

  The present invention relates to polymerisable compounds, to processes and intermediates for the preparation thereof, to liquid-crystal (LC) media comprising them, and to the use of the polymerisable compounds and LC media for optical, electro-optical and electronic purposes, in particular in LC displays, especially in LC displays of the polymer sustained alignment (PS, PSA) and self-aligning (SA) type.

  本发明涉及可聚合化合物，用于其制备的工艺和中间体，包括它们的液晶（LC）介质，以及可聚合化合物和LC介质在光学、电光和电子用途中的使用，特别是在LC显示器中，尤其是在聚合物维持定向（PS，PSA）和自对准（SA）类型的LC显示器中的使用。