N-(2,3-二甲基苯基)苯甲酰胺 | 3096-94-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: N-(2,3-二甲基苯基)苯甲酰胺
• 英文名称: N-(2,3-dimethylphenyl)benzamide
• 英文别名: benzoic acid-(2,3-dimethyl-anilide)；Benzoesaeure-(2,3-dimethyl-anilid)；2,3-Dimethyl-N-benzoyl-anilin；2',3'-Dimethyl-benzanilid
• CAS: 3096-94-4
• 化学式: C₁₅H₁₅NO
• mdl: MFCD00025936
• 分子量: 225.29
• InChiKey: KOKRWDZFZBINOW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.133
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N-(2,3-二甲基苯基)苯甲酰胺 在 copper(II) bis(trifluoromethanesulfonate) 、 双三氟甲烷磺酰亚胺 、 Selectfluor 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 3.5h， 以68%的产率得到5-methyl-2-phenyl-4H-benzo[d][1,3]oxazine
  参考文献：
  名称：

  的铜催化选择性苄型C-O环化ñ - ø -Tolylbenzamides：4的合成ħ -3,1-苯并恶嗪

  摘要：

  报道了一种新颖的Selectfluor介导的铜催化的高选择性苄基C–O环化反应，用于合成4 H -3,1-苯并恶嗪。在N - o-甲苯基苯甲酰胺中，相对于芳族C（sp 2）-H键，苄基C（sp 3）-H具有主要的选择性。

  DOI：

  10.1021/ol301492d
• 作为产物：
  描述：

  苯甲酸 生成 N-(2,3-二甲基苯基)苯甲酰胺
  参考文献：
  名称：

  摘要：

  DOI：

文献信息

• Cross-Dehydrogenating Coupling of Aldehydes with Amines/R-OTBS Ethers by Visible-Light Photoredox Catalysis: Synthesis of Amides, Esters, and Ureas
  作者：Ganesh Pandey、Suvajit Koley、Ranadeep Talukdar、Pramod Kumar Sahani

  DOI：10.1021/acs.orglett.8b02537

  日期：2018.9.21

  A straightforward synthesis of amides, ureas, and esters is reported by visible-light cross-dehydrogenating coupling (CDC) of aldehydes (or amine carbaldehydes) and amines/R-OTBS ethers by photoredox catalysis. The reaction is found to be general and high yielding. A plausible mechanistic pathway has been proposed for these transformations and is supported by appropriate controlled experiments.

  通过光氧化还原催化醛（或胺甲醛）和胺/ R-OTBS醚的可见光交叉脱氢偶联（CDC），报道了酰胺，脲和酯的直接合成。发现该反应是一般的且高收率的。已经为这些转化提出了一种可行的机理途径，并得到了适当的受控实验的支持。
• Synthesis of amides through an oxidative amidation of tetrazoles with aldehydes under transition-metal-free conditions
  作者：Juan Du、Kai Luo、Xiuli Zhang

  DOI：10.1039/c4ra07658c

  日期：——

  A simple, inexpensive and efficient one-pot synthesis of amides was achieved in good yields via the direct oxidative amidation of tetrazoles with aldehydes under transition-metal-free conditions.

  一个简单的，酰胺的廉价和有效的一锅合成在良好的产率获得通过与过渡金属-自由条件下醛四唑的直接氧化酰胺化。
• NOVEL CERCOSPORAMIDE DERIVATIVE
  申请人：Daiichi Sankyo Company, Limited

  公开号：EP1914229B1

  公开（公告）日：2010-06-16
• Buu-Hoi; Hoan, Recueil des Travaux Chimiques des Pays-Bas, 1949, vol. 68, p. 5,29
  作者：Buu-Hoi、Hoan

  DOI：——

  日期：——
• Social Psychological Models of Choice Behavior and Drivers' Left Turns
  作者：W. Andrew Harrell、Louise M. Spaulding

  DOI：10.1080/00224540109600583

  日期：2001.12

  The authors reanalyzed data from a simulated left-turn experiment (P A. Hancock, J. K. Caird, S. Shekhar, & M. Vercruyssen, 1991) to test the adequacy of the nonlinear Gray-Tallman satisfaction balance model of choice behavior (L. N. Gray & I. Tallman, 1984) in predicting left turns. Participants (Hancock et al., 1991) were 40 experienced U.S. drivers who were exposed to simulated oncoming traffic; the size of the vehicle (motorcycle, compact vehicle, full-sized vehicle, delivery truck), its speed (10-70 mph, or 16-112 kmph), and the intervehicle time gap (3-9 s) varied. Hancock et al. (1991) measured (a) the likelihood of a left turn and (b) the occurrence of a collision. The probability of a left turn was greater for larger intervehicle time gaps and for oncoming smaller vehicles traveling at higher speeds. The Gray-Tallman (1984) model explained 69% of the variation in turning versus 57% for a linear regression model. In making decisions people tend to treat the values and costs affecting choices in a multiplicative, rather than linear, fashion. The Gray-Tallman model also has the potential for incorporating, both theoretically and mathematically, an unlimited range of potential values and costs that may influence left turn decisions.