Amide-containing compound having improved solubility and method of improving the solubility of an amide-containing compound
申请人:——
公开号:US20040014967A1
公开(公告)日:2004-01-22
The present invention is directed to novel amide-containing compounds which have an improved solubility and a method of improving the solubility of amide-containing compounds. The amide-containing compounds include oxazolidinone compounds and the bioavailability of these oxazolidinone compounds is improved by improving the solubility thereof.
N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
申请人:——
公开号:US20040147760A1
公开(公告)日:2004-07-29
The present invention provides antibacterial agents having the formulae I, II, and III described herein.
本发明提供了具有以下式I、II和III的抗菌剂。
[EN] N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATIVES AND THEIR USE AS ANTIBACTERIALS<br/>[FR] N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES ET LEURS DERIVES ET UTILISATION DE CES COMPOSES COMME ANTIBACTERIENS
申请人:UPJOHN CO
公开号:WO2003072553A1
公开(公告)日:2003-09-04
Compounds of formula B-C-A-CO-NH-R1, wherein A is structure i, ii or iii: formulae (I), (II), (III). C is optionally substituted aryl or heteroaryl, and B is a specified cyclic moiety, or C and B together are a heterobicyclic moiety, are useful as antibacterial agents.