p-(1-Bromethyl)benzenesufonylchlorid | 25426-48-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: p-(1-Bromethyl)benzenesufonylchlorid
• 英文别名: 4-(1-bromo-ethyl)-benzenesulfonyl chloride；4-(1-Brom-aethyl)-benzolsulfonylchlorid；4-Bromethylbenzenesulphonyl chloride；p-(1-Bromo-ethyl)benzenesulfonyl chloride；4-(1-bromoethyl)benzenesulfonyl chloride
• CAS: 25426-48-6
• 化学式: C₈H₈BrClO₂S
• 分子量: 283.573
• InChiKey: LOXMFOAAJIFHEL-UHFFFAOYSA-N

物化性质

• 沸点：
  329.5±25.0 °C(Predicted)
• 密度：
  1.640±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  42.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  p-(1-Bromethyl)benzenesufonylchlorid 在 氢氧化钾 作用下， 生成 4-(1-hydroxy-ethyl)-benzenesulfonic acid
  参考文献：
  名称：

  Replacement Reactions of α-Bromoethylbenzenesulfonyl Chloride with Alkali

  摘要：

  DOI：

  10.1021/jo50016a017
• 作为产物：
  描述：

  乙基苯 在 四氯化碳 、 氯磺酸 、 溴 作用下， 反应 3.0h， 生成 p-(1-Bromethyl)benzenesufonylchlorid
  参考文献：
  名称：

  Moralli, Bulletin de la Societe Chimique de France, 1953, p. 1044

  摘要：

  DOI：

文献信息

• Certain sulfonamide heterobicyclic platelet activating factor antagonists
  申请人：British Bio-Technology Limited

  公开号：US05180723A1

  公开（公告）日：1993-01-19

  Compounds of general formula I; ##STR1## wherein: A.sup.1 is .dbd.N--, .dbd.CH-- or .dbd.CR.sup.1 --; A.sup.2 is .dbd.N--, .dbd.CH-- or .dbd.CR.sup.2 --; provided that, when one of A.sup.1 and A.sup.2 is a nitrogen atom, the other of A.sup.1 and A.sup.2 is other than a nitrogen atom; wherein the other variables are as defined in the specification and their pharmaceutically and veterinarily acceptable acid addition salts and hydrates are antagonists of platelet activating factor (PAF) and as such are useful in the treatment or amelioration of various diseases or disorders mediated by PAF.

  通式I的化合物；其中：A.sup.1为.dbd.N--，.dbd.CH--或.dbd.CR.sup.1--; A.sup.2为.dbd.N--，.dbd.CH--或.dbd.CR.sup.2--; 前提是，当A.sup.1和A.sup.2中的一个是氮原子时，另一个不是氮原子；其中其他变量如规范中定义的那样，它们的药用和兽医学可接受的酸盐和水合物是血小板活化因子（PAF）的拮抗剂，因此在治疗或改善由PAF介导的各种疾病或紊乱方面是有用的。
• Sodium<i>p</i>‐[1‐(<i>n</i>‐nonylthio) ethyl] benzene sulfonate: A new, third generation, biodegradable surfactant
  作者：M. A. Linter、L. Long

  DOI：10.1007/bf02544976

  日期：1969.11

  Synthesis of sodiump‐[1‐(n‐nonylthio)ethyl] benzene sulfonate has been achieved by two distinct routes, starting with ethylbenzene, in overall yields of 26% and 27%. Preliminary tests indicate a somwhat increased detergency to that of LAS, and superior biodegradability to LAS.

  摘要 从乙苯开始，通过两种不同的路线合成了钠-[1-(正壬硫基)乙基]苯磺酸，总产率分别为 26% 和 27%。初步测试表明，该产品的去污力略高于 LAS，生物降解性也优于 LAS。
• MULTIBRANCHED POLYMERS AND PROCESS FOR PRODUCTION THEREOF
  申请人：NIPPON SODA CO., LTD.

  公开号：EP1780224A1

  公开（公告）日：2007-05-02

  The present invention provides a multibranched polymer represented by the following formula (I), and a method for producing the multibranched polymer: wherein A represents an organic group having 3 or more branched chains, Xa represents a linking group containing any atom of Groups 14 to 16 in the Periodic Table, Y represents a functional group having a structure capable of having an active halogen atom, Q represents an arm moiety having a repeating unit derived from a polymerizable unsaturated bond, m1 represents any integer of 1 to the number of branched chains of A, m2 represents the number of branched chains of A, n1 represents an integer of 0 or 1 or more, and Ra represents an organic group which is not associated with the polymerization reaction.

  本发明提供了由下式（I）表示的多支化聚合物，以及生产这种多支化聚合物的方法： 其中 A 代表具有 3 个或 3 个以上支链的有机基团，Xa 代表含有元素周期表中第 14 至 16 族原子的连接基团，Y 代表具有可具有活性卤原子结构的官能团，Q 代表具有由可聚合不饱和键衍生的重复单元的臂分子，m1 代表 1 至 A 的支链数的任意整数，m2 代表 A 的支链数，n1 代表 0 或 1 或以上的整数，Ra 代表与聚合反应无关的有机基团。
• Multibrached Polymer and Method for Producing the Same
  申请人：Niitani Takeshi

  公开号：US20080214685A1

  公开（公告）日：2008-09-04

  The present invention provides a multibranched polymer represented by the following formula (I), and a method for producing the multibranched polymer: wherein A represents an organic group having 3 or more branched chains, X a represents a linking group containing any atom of Groups 14 to 16 in the Periodic Table, Y represents a functional group having a structure capable of having an active halogen atom, Q represents an arm moiety having a repeating unit derived from a polymerizable unsaturated bond, m 1 represents any integer of 1 to the number of branched chains of A, m 2 represents the number of branched chains of A, n 1 represents an integer of 0 or 1 or more, and R a represents an organic group which is not associated with the polymerization reaction.
• Multibranched polymer and method for producing the same
  申请人：Niitani Takeshi

  公开号：US20110152388A1

  公开（公告）日：2011-06-23

  A multibranched polymer represented by the following formula (I), and a method for producing the multibranched polymer: where A represents an organic group having 3 or more branched chains, X a represents a linking group containing any atom of Groups 14 to 16 in the Periodic Table, Y represents a functional group having a structure capable of having an active halogen atom, Q represents an arm moiety having a repeating unit derived from a polymerizable unsaturated bond, m 1 represents any integer of 1 to the number of branched chains of A, m 2 represents the number of branched chains of A, n 1 represents an integer of 0 or 1 or more, and R a represents an organic group that is not associated with the polymerization reaction.