3-imidazol-1-yl-N-(4-methoxyphenyl)propionamide | 930723-28-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-imidazol-1-yl-N-(4-methoxyphenyl)propionamide
• 英文别名: 3-imidazol-1-yl-N-(4-methoxyphenyl)propanamide
• CAS: 930723-28-7
• 化学式: C₁₃H₁₅N₃O₂
• 分子量: 245.281
• InChiKey: CHQGKKKQRZIQNC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  56.2
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-imidazol-1-yl-N-(4-methoxyphenyl)propionamide 、 二溴甲烷 以 四氢呋喃 为溶剂， 反应 48.0h， 以71%的产率得到1,1'-methylene-bis(3-N-(4-methoxyphenyl)propionamide-1H-imidazolium) dibromide
  参考文献：
  名称：

  Platinum(II) complexes with amide-functionalized NHC ligands

  摘要：

  We present the synthesis of neutral, amide-functionalized N-heterocyclic carbene (NHC) platinum(II) complexes with dianionic -N-C-NHC-C-NHC-N- (NC*C*N) tetradentate ligands. The imidazolium- and bisimidazolium bromide NHC ligand precursors with amide functionality in the side chain are reported together with the corresponding biscarbene bromido complexes and, after deprotonation, of the neutral NHC complexes without counterions. All compounds have been thoroughly characterized by standard techniques. (C) 2012 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2012.05.019
• 作为产物：
  描述：

  甲氧苯胺 在 三乙胺 作用下， 以 二氯甲烷 、 甲苯 为溶剂， 反应 2.0h， 生成 3-imidazol-1-yl-N-(4-methoxyphenyl)propionamide
  参考文献：
  名称：

  Platinum(II) complexes with amide-functionalized NHC ligands

  摘要：

  We present the synthesis of neutral, amide-functionalized N-heterocyclic carbene (NHC) platinum(II) complexes with dianionic -N-C-NHC-C-NHC-N- (NC*C*N) tetradentate ligands. The imidazolium- and bisimidazolium bromide NHC ligand precursors with amide functionality in the side chain are reported together with the corresponding biscarbene bromido complexes and, after deprotonation, of the neutral NHC complexes without counterions. All compounds have been thoroughly characterized by standard techniques. (C) 2012 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2012.05.019

文献信息

• Platinum(II) complexes with amide-functionalized NHC ligands
  作者：Yvonne Unger、Thomas Strassner

  DOI：10.1016/j.jorganchem.2012.05.019

  日期：2012.8

  We present the synthesis of neutral, amide-functionalized N-heterocyclic carbene (NHC) platinum(II) complexes with dianionic -N-C-NHC-C-NHC-N- (NC*C*N) tetradentate ligands. The imidazolium- and bisimidazolium bromide NHC ligand precursors with amide functionality in the side chain are reported together with the corresponding biscarbene bromido complexes and, after deprotonation, of the neutral NHC complexes without counterions. All compounds have been thoroughly characterized by standard techniques. (C) 2012 Elsevier B. V. All rights reserved.