4-phenyl-N,N-bis(prop-2-enyl)aniline | 204773-09-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-phenyl-N,N-bis(prop-2-enyl)aniline
• CAS: 204773-09-1
• 化学式: C₁₈H₁₉N
• 分子量: 249.356
• InChiKey: ZUICJDRZQKAXQY-UHFFFAOYSA-N

物化性质

• 沸点：
  384.6±41.0 °C(Predicted)
• 密度：
  1.001±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  19
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  4-phenyl-N,N-bis(prop-2-enyl)aniline 在 palladium on activated charcoal 甲烷磺酸 作用下， 以 乙醇 为溶剂， 以84%的产率得到4-氨基联苯
  参考文献：
  名称：

  Allyl amines as ammonia equivalents in the preparation of anilines and heteroarylamines

  摘要：

  A series of anilines and heteroarylamines were synthesized in moderate to excellent yields by palladium catalyzed cross coupling reaction of aryl or heteroaryl halides with allyl-or N,N-diallylamine followed by deallylation. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(97)10877-2
• 作为产物：
  描述：

  4-溴代联苯 、 二烯丙基胺 在 二氯双(三邻甲苯膦)合钯(II) sodium t-butanolate 作用下， 以 甲苯 为溶剂， 反应 3.0h， 以37%的产率得到4-phenyl-N,N-bis(prop-2-enyl)aniline
  参考文献：
  名称：

  Allyl amines as ammonia equivalents in the preparation of anilines and heteroarylamines

  摘要：

  A series of anilines and heteroarylamines were synthesized in moderate to excellent yields by palladium catalyzed cross coupling reaction of aryl or heteroaryl halides with allyl-or N,N-diallylamine followed by deallylation. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(97)10877-2

文献信息

• Selective Conversion of Diallylanilines and Arylimines to Quinolines
  作者：Josemon Jacob、William D. Jones

  DOI：10.1021/jo026737j

  日期：2003.5.1

  A variety of diallylanilines are shown to undergo cobalt-carbonyl catalyzed rearrangement to quinolines. Diallylanilines are also used as allyl transfer reagents to convert benzaldimines into quinolines. Substitution in the 2- and 3-positions of the quinoline is featured in all transformations.
• US5069999A
  申请人：——

  公开号：US5069999A

  公开（公告）日：1991-12-03
• Allyl amines as ammonia equivalents in the preparation of anilines and heteroarylamines
  作者：Saul Jaime-Figueroa、Yanzhou Liu、Joseph M. Muchowski、David G. Putman

  DOI：10.1016/s0040-4039(97)10877-2

  日期：1998.3

  A series of anilines and heteroarylamines were synthesized in moderate to excellent yields by palladium catalyzed cross coupling reaction of aryl or heteroaryl halides with allyl-or N,N-diallylamine followed by deallylation. (C) 1998 Elsevier Science Ltd. All rights reserved.