3-羰基-N-(3-苯基-丙基)-丁酰胺 | 112369-47-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 3-羰基-N-(3-苯基-丙基)-丁酰胺
• 英文名称: 3-oxo-N-(3-phenylpropyl)-butylamide
• 英文别名: 3-oxo-N-(3-phenylpropyl)butyramide；3-oxo-N-(3-phenylpropyl) butylamide；3-oxo-N-(3-phenylpropyl)butanamide
• CAS: 112369-47-8
• 化学式: C₁₃H₁₇NO₂
• mdl: MFCD00026264
• 分子量: 219.283
• InChiKey: XXOBEWUNERKREQ-UHFFFAOYSA-N

物化性质

• 沸点：
  418.7±38.0 °C(Predicted)
• 密度：
  1.055±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.384
• 拓扑面积：
  46.2
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 海关编码：
  2924299090

反应信息

• 作为反应物：
  描述：

  3-羰基-N-(3-苯基-丙基)-丁酰胺 在 三乙胺 、 三氯化磷 作用下， 以 甲醇 、 氯仿 为溶剂， 反应 10.0h， 生成 3-Methyl-1-oxy-quinoxaline-2-carboxylic acid (3-phenyl-propyl)-amide
  参考文献：
  名称：

  Sabri, Salim S.; El-Abadelah, Mustafa M.; Al-Bitar, Bassam A., Heterocycles, 1987, vol. 26, # 3, p. 699 - 711

  摘要：

  DOI：
• 作为产物：
  描述：

  双乙烯酮 、 3-苯基-1-丙胺 在 三乙胺 作用下， 以 甲苯 为溶剂， 反应 3.0h， 以71%的产率得到3-羰基-N-(3-苯基-丙基)-丁酰胺
  参考文献：
  名称：

  Pyrimidine derivatives and new pyridine derivatives

  摘要：

  Achirai嘧啶衍生物和以下结构式或其类似物的吡啶衍生物具有选择性N型钙通道拮抗活性，并在口服时显示镇痛作用。它们可用作与N型钙通道相关的疼痛和各种疾病的治疗药物。

  公开号：

  US20040009991A1

文献信息

• NOVEL PYRIMIDINE DERIVATIVE AND NOVEL PYRIDINE DERIVATIVE
  申请人：Ajinomoto Co., Inc.

  公开号：EP1318147A1

  公开（公告）日：2003-06-11

  Achiral pyrimidine derivatives and pyridine derivatives of the following formulae or analogs thereof have selective N-type calcium channel antagonistic activity and showed analgesic action when they were taken orally. They are useful as therapeutic agents for pains and various diseases associated with the N-type calcium channels.

  非手性嘧啶衍生物和以下结构式或其类似物的吡啶衍生物具有选择性N型钙通道拮抗活性，并且当口服时表现出镇痛作用。它们可用作与N型钙通道相关的疼痛和各种疾病的治疗药物。
• Dihydropyrimidine compounds and compositions containing the same
  申请人：AJINOMOTO CO. INC

  公开号：US20020143023A1

  公开（公告）日：2002-10-03

  Dihydropyrimidine derivatives of the following formula or analogs thereof have selective N-type calcium channel antagonistic activity, and they are used as therapeutic agents for various diseases participating in the N-type calcium channels. 1

  二氢嘧啶衍生物具有以下结构式或其类似物具有选择性N型钙通道拮抗活性，并且它们被用作参与N型钙通道的各种疾病的治疗药物。
• Thiophene Azo Dyes and Laundry Care Compositions Containing the Same
  申请人：Torres Eduardo

  公开号：US20120123101A1

  公开（公告）日：2012-05-17

  This application relates to thiophene azo dyes for use as hueing agents, laundry care compositions comprising such thiophene azo dyes, processes for making such thiophene azo dyes, and laundry care compositions and methods of using the same. The thiophene azo dyes contain a formally charged moiety and are generally comprised of at least two components: at least one chromophore component and at least one polymeric component. Suitable chromophore components generally fluoresce blue, red, violet, or purple color when exposed to ultraviolet light, or they may absorb light to reflect these same shades. These thiophene azo dyes are advantageous in providing a hueing effect, for example, a whitening effect to fabrics, while not building up over time and causing undesirable blue discoloration to the treated fabrics. The thiophene azo dyes are also generally stable to bleaching agents used in laundry care compositions.

  本申请涉及用作着色剂的噻吩偶氮染料，包括含有这种噻吩偶氮染料的洗涤护理组合物，制备这种噻吩偶氮染料的方法，以及包含这种噻吩偶氮染料的洗涤护理组合物和使用方法。这些噻吩偶氮染料含有一个形式上带电的基团，通常由至少两个组分组成：至少一个色团组分和至少一个聚合物组分。适用的色团组分通常在紫外光照射下呈蓝色、红色、紫色或紫色，或者它们可以吸收光线以反射这些相同的色调。这些噻吩偶氮染料在提供着色效果方面具有优势，例如，对织物产生美白效果，同时不会随时间累积并导致处理过的织物产生不良的蓝色变色。这些噻吩偶氮染料通常对洗涤护理组合物中使用的漂白剂具有稳定性。
• Thiophene Azo Carboxylate Dyes and Laundry Care Compositions Containing the Same
  申请人：Torres Eduardo

  公开号：US20120309945A1

  公开（公告）日：2012-12-06

  This application relates to thiophene azo carboxylate dyes for use as hueing agents, laundry care compositions comprising such dyes that may serve as hueing agents, processes for making such dyes and laundry care compositions and methods of using the same. The aforementioned dyes contain a formally charged moiety and are generally comprised of at least two components: at least one chromophore component and at least one polymeric component. Suitable chromophore components generally fluoresce blue, red, violet, or purple color when exposed to ultraviolet light, or they may absorb light to reflect these same shades. Such dyes are advantageous in providing a hueing effect, for example, a whitening effect to fabrics, while not building up over time and causing undesirable blue discoloration to the treated fabrics. Such dyes are also generally stable to bleaching agents used in laundry care compositions.

  本申请涉及噻吩偶氮羧酸酯染料作为色调剂的用途，包括含有此类染料的洗涤保养组合物可作为色调剂，制备此类染料和洗涤保养组合物的方法以及使用它们的方法。前述染料含有一个形式上带电的基团，通常由至少两个组分组成：至少一个色团组分和至少一个聚合物组分。适当的色团组分通常在紫外光下照射时发出蓝色、红色、紫色或紫色的荧光，或者它们可以吸收光线以反射这些相同的色调。这种染料在提供色调效果方面具有优势，例如，对织物具有美白效果，同时不会随着时间的推移而积累并导致处理过的织物产生不良的蓝色变色。此类染料通常也稳定于洗涤保养组合物中使用的漂白剂。
• NEW PYRIMIDINE DERIVATIVES AND NEW PYRIDINE DERIVATIVES
  申请人：OHNO Seiji

  公开号：US20080070903A1

  公开（公告）日：2008-03-20

  Achiral pyrimidine derivatives and pyridine derivatives of the following formulae or analogs thereof have selective N-type calcium channel antagonistic activity and showed analgesic action when they were taken orally. They are useful as therapeutic agents for pains and various diseases associated with the N-type calcium channels.

  以下式子或其类似物的非手性嘧啶衍生物和吡啶衍生物具有选择性N型钙通道拮抗活性，并且口服时表现出镇痛作用。它们可用作治疗与N型钙通道相关的疼痛和各种疾病的治疗剂。