perfluoro(3,6-dioxaoctanoyl) fluoride | 13071-65-3

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 酰卤
• 英文名称: perfluoro(3,6-dioxaoctanoyl) fluoride
• 英文别名: Difluoro-2-[2-(pentafluoroethoxy)tetrafluoroethoxy]acetyl fluoride；2,2-difluoro-2-[1,1,2,2-tetrafluoro-2-(1,1,2,2,2-pentafluoroethoxy)ethoxy]acetyl fluoride
• CAS: 13071-65-3
• 化学式: C₆F₁₂O₃
• 分子量: 348.045
• InChiKey: DINZHUNGJCQOIS-UHFFFAOYSA-N

物化性质

• 沸点：
  65-67 °C
• 密度：
  1.714±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  21
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  15

反应信息

• 作为反应物：
  描述：

  perfluoro(3,6-dioxaoctanoyl) fluoride 在 水 作用下， 以100%的产率得到3,6-dioxa-F-octanoic acid
  参考文献：
  名称：

  [EN] PROCESS FOR THE MANUFACTURE OF FLUOROSURFACTANTS
  [FR] PROCÉDÉ DE FABRICATION DE TENSIOACTIFS FLUORÉS

  摘要：

  这项发明涉及一种用于制造化学式（I）的全氟氧羧酸酯的新工艺：RfO-CF2CF2-O-CF2-COOXa（I），其中Rf是全氟（氧）烷基基团，Xa是H，一价金属或化学式NRN4的铵基团，其中RN在每次出现时可以相同也可以不同，为H或C1-6碳氢基团，所述工艺包括：（A）将化学式Rf-O-CF=CF2的全氟乙烯醚与乙二醇衍生物反应，所述乙二醇衍生物从乙二醇（HO-CH2CH2-OH）、乙二酸（HO-CH2-COOH）、乙醛（HO-CH2-CHO）及其保护衍生物中选择，以产生相应的加成产物，化学式为Rf-O-CFH-CF2-O-CH2-E，其中Rf的含义与上述详细相同，E从-CH2OH、-COOH和-CHO中选择；（B）可选地用适当的化学方法保护官能团E；（C）氟化所述（保护的）加成产物以产生相应的全氟化加成产物；（D）可选地去保护所述全氟化加成产物以产生化学式为Rf-O-CF2-CF2-O-CF2-C（O）F的相应酰氟化合物；（E）水解和可选地中和所述酰氟化合物以产生化学式（I）的全氟氧羧酸酯。

  公开号：

  WO2010003931A1
• 作为产物：
  描述：

  Difluoro-[1,1,2,2-tetrafluoro-2-(1,1,2,2-tetrafluoro-2-pentafluoroethyloxy-ethoxy)-ethoxy]-acetic acid difluoro-[1,1,2,2-tetrafluoro-2-(1,1,2,2-tetrafluoro-2-pentafluoroethyloxy-ethoxy)-ethoxy]-methyl ester 生成 perfluoro(3,6-dioxaoctanoyl) fluoride
  参考文献：
  名称：

  BRACE, N. O., J. FUOR. CHEM., 1981, 18, N 4, 515-524

  摘要：

  DOI：

文献信息

• Some approaches to the synthesis of fluorinated alcohols and esters. I. Completely fluorinated esters from the hunsdiecker reaction of silver F-alkanoates with iodine
  作者：Neal O. Brace

  DOI：10.1016/s0022-1139(00)82668-8

  日期：1981.10

  A completely fluorinated ester of the type RFCO2CF2RF′ was obtained from reaction of silver 3,6,9-trioxa-F-undecanoate and iodine with a diluent at 130°. This new substance resembled closely the previously prepared 1,1-dichloro-F-alkyl esters and was hydrolytically and thermally labile. Substitution products, RFCOY (Y = nucleophile) and pyrolysis products, RFCOF and RF′COF were isolated and characterized

  由3,6,9-三氧杂-F-十一酸银和碘与稀释剂在130°C下反应制得R F CO 2 CF 2 R F '型的完全氟化酯。这种新物质非常类似于先前制备的1,1-二氯-F-烷基酯，并且水解和热不稳定。取代产物，R ˚F COY（Y =亲核）和热解产物，R ˚F COF和R ˚F 'COF进行分离和表征。似乎酰基次碘酸盐和碘代-F-烷烃通过S E i型过程反应生成了完全氟化的酯。
• ETHERIC (ETHEREAL) OXYGEN ATOM-CONTAINING PERFLUOROALKYL GROUP-SUBSTITUTED PYRIMIDINE RING COMPOUND, AND METHOD FOR ITS PRODUCTION
  申请人：ASAHI GLASS COMPANY, LIMITED

  公开号：US20170050934A1

  公开（公告）日：2017-02-23

  To provide a pyrimidine derivative having a fluorinated substituent group, that can be applied to an agricultural chemical or pharmaceutical having excellent pharmacological activities, and a method for producing said derivative. A compound represented by the following formula (A). R f is a group having an etheric (ethereal) oxygen atom inserted between carbon-carbon atoms in a C 2-19 perfluoroalkyl group, wherein the total of the number of carbon atoms and the number of oxygen atoms is from 3 to 20. R 1 is a C 1-6 alkyl group, etc. Q 1 is R 2 C(O)—, R 3 OC(O)—, a carboxy group, R 4 OC(O)NH—, an amino group, or R 5 C(O)NH—(R 2 to R 5 are each independently a C 1-6 alkyl group, etc.).

  提供一种具有氟代取代基的嘧啶衍生物，可应用于具有优异药理活性的农药或药物，并提供一种制备该衍生物的方法。以下是表示的化合物（A）的公式。Rf是一个在C2-19全氟烷基中的碳-碳原子之间插入了醚氧原子的基团，其中碳原子数和氧原子数的总和为3到20。R1是C1-6烷基基团等。Q1是R2C(O)—，R3OC(O)—，一个羧基，R4OC(O)NH—，一个氨基，或R5C(O)NH—（R2到R5分别是独立的C1-6烷基基团等）。
• ETHEREAL OXYGEN ATOM-CONTAINING PERFLUOROALKYL GROUP-SUBSTITUTED PYRAZOLE RING COMPOUND AND METHOD FOR ITS PRODUCTION
  申请人：ASAHI GLASS COMPANY, LIMITED

  公开号：US20160295864A1

  公开（公告）日：2016-10-13

  To provide a pyrazole derivative having a superior fluorinated substituent, which is useful for pharmaceutical products or agricultural chemicals having pharmacological activities, and a method for its production. A compound represented by the following formula (A), wherein R f is a C 2-19 perfluoroalkyl group having ethereal oxygen atom(s) inserted between carbon-carbon atoms of the group, and the total number of carbon atoms and oxygen atoms in R f being from 3 to 20, one of Q 1 and Q 2 is a hydrogen atom, and the other is a phenyl group, or a phenyl group in which at least one hydrogen atom in the phenyl group is each independently substituted by a halogen atom, and one of A 1 and A 2 is a nitrogen atom, and the other is a nitrogen atom to which R 1 is bonded.

  提供一种具有优越氟代取代基的吡唑衍生物，适用于具有药理活性的制药产品或农用化学品，并提供其生产方法。所述化合物由以下式（A）表示，其中Rf是具有乙醚氧原子插入其碳-碳原子之间的C2-19全氟烷基基团，Rf中的碳原子和氧原子的总数为3至20，Q1和Q2中的一个是氢原子，另一个是苯基，或者至少一个苯基中的氢原子各自独立地被卤素原子取代，A1和A2中的一个是氮原子，另一个是与R1键合的氮原子。
• Halogenated acrylates and polymers derived therefrom
  申请人：3M Innovative Properties Company

  公开号：US20010037028A1

  公开（公告）日：2001-11-01

  Acrylates having a high degree of halogenation, as well as polymers that include one or more mer units derived from such acrylates provide materials having tailorable optical and physical properties. The polymers find utility particularly in optical devices including optical waveguides and interconnecting devices.

  具有高度卤化度的丙烯酸酯，以及包括一个或多个源自这种丙烯酸酯的聚合物单元的聚合物，提供具有可调光学和物理特性的材料。这些聚合物特别适用于包括光波导和互连装置在内的光学器件。
• LIQUID REPELLENT COMPOUND, LIQUID REPELLENT POLYMER, CURABLE COMPOSITION, COATING COMPOSITION, ARTICLE HAVING CURED FILM, ARTICLE HAVING PATTERN WITH LYOPHILIC REGION AND LIQUID REPELLENT REGION, AND METHOD FOR PRODUCING SAME
  申请人：Asahi Glass Company, Limited

  公开号：EP2792665A1

  公开（公告）日：2014-10-22

  To provide a curable composition which has favorable insulating property and liquid repellency, and from which a cured film having liquid repellency capable of being sufficiently converted to be liquid-philic even by irradiation with ultraviolet light having a wavelength of at least 300 nm, can be formed, an article having a cured film obtained by curing the curable composition and its production process. A cured film is formed by using a curable composition comprising a liquid repellent polymer having units (u1) based on a liquid repellent compound represented by the following formula (m1): wherein Cf is a C1-20 fluoroalkyl group or a C1-20 fluoroalkyl group having an etheric oxygen atom between carbon atoms, each of R1 and R2 which are independent of each other, is a hydrogen atom, a C1-6 alkyl group or a phenyl group, X is an oxygen atom, a sulfur atom, a nitrogen atom or NH, n in an integer of from 0 to 4, m is 1 when X is an oxygen atom, a sulfur atom or NH, or 2 when X is a nitrogen atom, Z is R4R5C=CR3-CO-, and each of R3, R4 and R5 which are independent of one another, is a hydrogen atom or a methyl group.

  提供一种可固化组合物，该组合物具有良好的绝缘性能和憎液性能，并能形成即使用波长至少为 300 纳米的紫外线照射也能充分转化为亲液的憎液固化膜，还提供一种具有通过固化该可固化组合物而获得的固化膜的物品及其生产工艺。 固化膜是通过使用一种可固化组合物形成的，该组合物包含一种具有单元 (u1) 的憎液聚合物，该单元基于下式 (m1) 所代表的憎液化合物： 其中 Cf 是 C1-20 氟烷基或在碳原子之间有一个醚氧原子的 C1-20 氟烷基、 相互独立的 R1 和 R2 各为氢原子、C1-6 烷基或苯基、 X 是氧原子、硫原子、氮原子或 NH、 n 为 0 至 4 的整数、 当 X 为氧原子、硫原子或 NH 时，m 为 1；当 X 为氮原子时，m 为 2、 Z 是 R4R5C=CR3-CO- ，以及 相互独立的 R3、R4 和 R5 各为氢原子或甲基。