5-(1,2-dimethylheptyl)resorcinol | 10436-52-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 5-(1,2-dimethylheptyl)resorcinol
• 英文别名: 5-<3-Methyl-oxtyl-(2)>-resorcin；threo-5-(1,2-dimethylheptyl)resorcinol；5-(3-methyloctan-2-yl)benzene-1,3-diol
• CAS: 10436-52-9
• 化学式: C₁₅H₂₄O₂
• 分子量: 236.354
• InChiKey: LFAMTYOOZUPASP-UHFFFAOYSA-N

物化性质

• 沸点：
  167-169 °C(Press: 1 Torr)
• 密度：
  1.002±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  17
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  5-(1,2-dimethylheptyl)resorcinol 以61%的产率得到3,5-dimethyl-6-[2,6-dihydroxy-4-(3-methyl-2-octyl)phenyl]-2-piperidone
  参考文献：
  名称：

  6A-Azacannabinoids

  摘要：

  该化合物的化学式为##STR1##其中n = 2或3；R.sub.1是C.sub.3-C.sub.20烷基或芳基烷基；R.sub.2是低烷基或苯基；R.sub.3为H或替换(CH.sub.2).sub.n中的氢原子为CH.sub.3；m为1、2或4。这些化合物具有中枢神经系统活性，并可用作抗抑郁剂。

  公开号：

  US04025512A1
• 作为产物：
  描述：

  3-methyl-2-(3,5-dimethoxyphenyl)-octane 在 氢溴酸 、 溶剂黄146 作用下， 生成 5-(1,2-dimethylheptyl)resorcinol
  参考文献：
  名称：

  四氢大麻酚同系物。

  摘要：

  DOI：

  10.1021/ja01182a067

文献信息

• Pharmaceutical compositions containing alryl substituted cyclopenta
  申请人：Sharps Associates

  公开号：US03992550A1

  公开（公告）日：1976-11-16

  1,2,3,4-Tetrahydrocyclopenta[c] [1]benzopyrans of the formulae ##SPC1## Wherein R is a lower alkyl group having 1 to 5 carbons, R.sub.1 is hydrogen or a lower alkyl group having 1 to 5 carbons, R.sub.2 is a lower alkyl group and R.sub.3 is an alkyl group having 1 to 20 carbon atoms, a phenyl-lower alkyl group or a cycloalkyl-lower alkyl group. The compounds have anti-hypertensive, antidepressant, analgesic, anticonvulsant, anti-anxiety and tranquilizing activity in animals.

  1,2,3,4-四氢环戊[c][1]苯并吡喃的化学式为##SPC1##其中R是具有1至5个碳的较低烷基基团，R.sub.1是氢或具有1至5个碳的较低烷基基团，R.sub.2是较低烷基基团，R.sub.3是具有1至20个碳原子的烷基基团，苯基-较低烷基基团或环烷基-较低烷基基团。这些化合物在动物中具有抗高血压、抗抑郁、镇痛、抗抽搐、抗焦虑和镇静活性。
• Heterocyclic esters of benzopyrans
  申请人：Sharps Associates

  公开号：US03941782A1

  公开（公告）日：1976-03-02

  This invention relates to novel esters of benzopyrans represented by the formulae ##SPC1## Wherein R and R' are hydrogen or C.sub.1 -C.sub.6 alkyl and when alkyl are on the same or different carbons; R.sub.1 is C.sub.1 -C.sub.6 alkyl; R.sub.2 is C.sub.1 -C.sub.20 alkyl, lowercycloalkyloweralkyl or lowercycloalkyl; n is an integer from 3 to 7, and particularly 3 to 5; Y is a straight or branched chain C.sub.1 -C.sub.8 alkylene; and R.sub.3 is ##EQU1## WHEREIN A IS AN INTEGER FROM 1 TO 4, B IS AN INTEGER FROM 1 TO 4, X is O,S, CH.sub.2 or NR.sub.4 and R.sub.4 is hydrogen C.sub.1 -C.sub.6 alkyl, and R.sub.5 is hydrogen or C.sub.1 -C.sub.6 alkyl; and the acid addition salts thereof. The compounds exhibit analgesic and central nervous system activity.

  这项发明涉及由以下式表示的新型苯并吡喁酯 ##SPC1## 其中R和R'为氢或C.sub.1 -C.sub.6烷基，当烷基位于相同或不同的碳上时；R.sub.1为C.sub.1 -C.sub.6烷基；R.sub.2为C.sub.1 -C.sub.20烷基，较低的环烷烃较低的烷基或较低的环烷烃；n为3到7的整数，特别是3到5；Y为直链或支链C.sub.1 -C.sub.8亚烷基；R.sub.3为##EQU1## 其中A为1到4的整数，B为1到4的整数，X为O、S、CH.sub.2或NR.sub.4，R.sub.4为氢C.sub.1 -C.sub.6烷基，R.sub.5为氢或C.sub.1 -C.sub.6烷基；以及它们的酸盐。这些化合物表现出镇痛和中枢神经系统活性。
• 3-Alkyl xanthene compounds
  申请人：SmithKline Corporation

  公开号：US03931232A1

  公开（公告）日：1976-01-06

  The compounds of this invention are 3-alkyl xanthenes having pharmacological activity such as central nervous system activity. Preferred compounds of this invention are 3-(1,2-dimethylheptyl)-5,6,7,8-tetrahydro-1-hydroxy-9-methylxanthene, 3-(1,2-dimethylheptyl)-1-hydroxy-6,9-dimethylxanthene and 3-(1,2-dimethylheptyl)-1-hydroxy-9-methylxanthene.

  本发明的化合物是具有药理活性的3-烷基黄色素，如中枢神经系统活性。本发明的优选化合物是3-(1,2-二甲基庚基)-5,6,7,8-四氢-1-羟基-9-甲基黄色素，3-(1,2-二甲基庚基)-1-羟基-6,9-二甲基黄色素和3-(1,2-二甲基庚基)-1-羟基-9-甲基黄色素。
• Esters of thienobenzopyrans and thiopyranobenzopyrans
  申请人：Sharps Associates

  公开号：US03960871A1

  公开（公告）日：1976-06-01

  Novel thienobenzopyran and thiopyranobenzopyran esters represented by the formula ##SPC1## Wherein n is 0 to 3 and m is 0 to 3 and m + n = 2 or 3, R.sub.1 is lower alkyl, R.sub.2 is alkyl or cycloalkyl-lower alkyl, R.sub.4 is hydrogen or lower alkyl, R.sub.5 is hydrogen or lower alkyl, and R.sub.3 is ##EQU1## wherein Y is a straight or branched chain C.sub.1 to C.sub.8 alkylene, R.sub.6 is hydrogen or a lower alkyl, a is an integer from 1 to 4, b is an integer from 1 to 4, X is CH.sub.2, O, S or NR.sub.7 wherein R.sub.7 is hydrogen or lower alkyl, with the limitation that when X is O, S or NR.sub.7, a and b each must be 2; and the acid addition salts thereof.

  新颖的噻吲并苯并吡喃酯和噻吲并苯并吡喃酯的化学式为##SPC1## 其中n为0至3，m为0至3，且m + n = 2或3，R.sub.1为较低的烷基，R.sub.2为烷基或环烷基-较低的烷基，R.sub.4为氢或较低的烷基，R.sub.5为氢或较低的烷基，R.sub.3为##EQU1## 其中Y为直链或支链C.sub.1至C.sub.8的烷基，R.sub.6为氢或较低的烷基，a为1至4的整数，b为1至4的整数，X为CH.sub.2、O、S或NR.sub.7，其中R.sub.7为氢或较低的烷基，限制条件是当X为O、S或NR.sub.7时，a和b必须分别为2；及其酸盐。
• MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME
  申请人：TABATA Masayoshi

  公开号：US20110224343A1

  公开（公告）日：2011-09-15

  The present invention provides a modifier for aromatic polyesters which enhances the melt fluidity of aromatic polyesters without a significant decrease in the heat resistance of the aromatic polyesters, and an aromatic polyester resin composition including the modifier for aromatic polyesters. The present invention relates to a modifier for aromatic polyesters comprising polyhydric phenol residues and residues of aromatic polycarboxylic acid, acid halide or acid anhydride thereof, and the modifier comprises a material having a structure composed of a first residue selected from the group consisting of divalent residues represented by Formula (I): —Ar—W 1 x —Ar— and by Formula (II): —Ar—, the first residues being bonded to two identical or different second residues selected from the group consisting of monovalent residues represented by Formula (III): and monovalent residues represented by Formula (IV): —O—C(O)—R 7 —.

  本发明提供了一种用于芳香族聚酯的改性剂，可以增强芳香族聚酯的熔融流动性，而不明显降低芳香族聚酯的耐热性，以及包括该改性剂的芳香族聚酯树脂组合物。本发明涉及一种用于芳香族聚酯的改性剂，包括多羟基酚残基和芳香族多羧酸、酸卤或其酸酐残基，该改性剂包括具有以下结构的材料：第一残基，选择自由式(I)所代表的二价残基：—Ar—W1x—Ar—和自由式(II)所代表的：—Ar—，第一残基与选择自由式(III)所代表的单价残基：和自由式(IV)所代表的单价残基：—O—C(O)—R7—的两个相同或不同的第二残基结合。