8-(Thiophen-2-yl)octan-1-ol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 杂芳族化合物
• 英文名称: 8-(Thiophen-2-yl)octan-1-ol
• 英文别名: 8-thiophen-2-yloctan-1-ol
• 化学式: C₁₂H₂₀OS
• 分子量: 212.356
• InChiKey: XQXQEBXJZQWTST-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  14
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  48.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  8-(Thiophen-2-yl)octan-1-ol 在 溶剂黄146 、 pyridinium chlorochromate 作用下， 以 甲醇 、 二氯甲烷 为溶剂， 反应 20.17h， 生成 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(8-thiophen-2-yloctyl)piperidine-3,4,5-triol
  参考文献：
  名称：

  [EN] IMINOSUGARS USEFUL FOR THE TREATMENT OF VIRAL DISEASES
  [FR] IMINOSUCRES UTILES POUR LE TRAITEMENT DE MALADIES VIRALES

  摘要：

  公开号：

  WO2016073652A8
• 作为产物：
  描述：

  1-bromo-8-[(tert-butyldimethylsilyl)oxy]octane 在 2,2'-联吡啶 、 正丁基锂 、 四丁基氟化铵 作用下， 以 四氢呋喃 为溶剂， 反应 29.67h， 生成 8-(Thiophen-2-yl)octan-1-ol
  参考文献：
  名称：

  [EN] IMINOSUGARS USEFUL FOR THE TREATMENT OF VIRAL DISEASES
  [FR] IMINOSUCRES UTILES POUR LE TRAITEMENT DE MALADIES VIRALES

  摘要：

  公开号：

  WO2016073652A8

文献信息

• Anti-inflammatory furanones
  申请人：Allergan, Inc.

  公开号：US05134128A1

  公开（公告）日：1992-07-28

  New 5-hydroxy-2-furanone compounds having anti-inflammatory, immunosuppressive and anti-proliferative activity and are useful in treating psoriasis and modifying calcium homeostasis.

  新的具有抗炎、免疫抑制和抗增殖活性的5-羟基-2-呋喃酮化合物对治疗牛皮癣和调节钙稳态具有用处。
• Modified Phenolic Resin, Epoxy Resin Composition Containing the Same, and Prepreg Containing the Composition
  申请人：Abe Takaharu

  公开号：US20080044667A1

  公开（公告）日：2008-02-21

  The modified phenolic resin of the present invention has a specific structure in which a side chain of an aromatic ring having a hydroxyl group in a phenolic resin that is an alternate copolymer of a phenolic compound and a compound having a divalent connecting group, is substituted with a group represented by general formula (1-1). By using the modified phenolic resin as a hardener for epoxy resins, there are provided an epoxy resin, a composition thereof, and a cured product thereof having excellent adhesion and flame retardancy without impairing properties of conventional phenolic resins such as gel time, glass transition temperature, moisture absorption, and mechanical properties. (In the formula, R 1 represents a C 1-8 linear, branched, or cyclic hydrocarbon group.) The present invention provides an epoxy resin composition with excellent adhesion and flame retardancy in uses such as hardeners for semiconductor sealing epoxy resins, insulating materials for electrical/electronic components, and laminates (printed circuit boards). A prepreg containing a glass substrate impregnated with the epoxy resin composition, a laminate, and an electronic circuit board are also provided.
• BIOSENSOR COMPRISING LINKER MATERIAL AND QUANTUM DOT BEADS, AND TARGET ANTIGEN DETECTION METHOD USING SAME
  申请人：ZEUS CO., LTD.

  公开号：US20210072239A1

  公开（公告）日：2021-03-11

  One aspect of the present disclosure relates to an immunochromatographic detection method for a target antigen in a biological sample, comprising the step of joining a linker having a first antibody and a quantum dot bead having a second antibody, with respect to the target antigen. By using the quantum dot beads and the linker, the method can successfully amplify detection strength and significantly increase detection sensitivity through a simple process without causing the loss of antigens participating in the detection when using only quantum dot beads. Furthermore, the present disclosure can significantly amplify detection strength without an additional washing step, thus enabling excellent detection and identification of a physiological substance in a biological sample, even in an actual product, and can be used to provide a product with a competitive price.
• QUANTUM DOT BEAD HAVING MULTIFUNCTIONAL LIGAND, AND TARGET ANTIGEN DETECTION METHOD AND BIO-DIAGNOSTIC APPARATUS USING SAME
  申请人：ZEUS CO., LTD.

  公开号：US20210080454A1

  公开（公告）日：2021-03-18

  In one aspect, the present disclosure relates to a quantum dot bead comprising a multifunctional ligand having a first binding material and a second antibody, and an immunochromatographic detection method for a target antigen in a biological sample, comprising forming multiple bonds with a quantum dot having a second binding material. In addition, the present disclosure has the effect of remarkably amplifying the detection intensity and significantly improving the detection sensitivity without a separate washing step, and thus enables the detection and diagnosis of physiological materials in a biological sample even in an actual product, and may be used to provide a product with excellent competitiveness in price.
• US5134128A
  申请人：——

  公开号：US5134128A

  公开（公告）日：1992-07-28