3,4,6,3',4',6'-hexachloro-2,2'-sulfanediyl-di-phenol | 3161-14-6

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 3,4,6,3',4',6'-hexachloro-2,2'-sulfanediyl-di-phenol
• 英文别名: 3,4,6,3',4',6'-Hexachlor-2,2'-sulfandiyl-di-phenol；Bis-(3.5.6-trichlor-2-hydroxy-phenyl)-sulfid；2,2'-Dihydroxy-3,3',5,5',6,6'-hexachlor-diphenylsulfid；Bis-(3,5,6-trichlor-2-hydroxyphenyl)sulfid；6,6'-Thiobis(2,4,5-trichlorophenol)；3,4,6-trichloro-2-(2,3,5-trichloro-6-hydroxyphenyl)sulfanylphenol
• CAS: 3161-14-6
• 化学式: C₁₂H₄Cl₆O₂S
• 分子量: 424.947
• InChiKey: FLBPYLKSSDOEOO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.8
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  65.8
• 氢给体数：
  2
• 氢受体数：
  3

安全信息

• 海关编码：
  2930909090

反应信息

• 作为反应物：
  描述：

  3,4,6,3',4',6'-hexachloro-2,2'-sulfanediyl-di-phenol 在 双氧水 、 溶剂黄146 作用下， 生成 3,4,6,3',4',6'-hexachloro-2,2'-sulfinyl-di-phenol
  参考文献：
  名称：

  2-Hydroxyphenyl Sulfoxides and 2-Hydroxyphenyl Sulfones

  摘要：

  DOI：

  10.1021/ja01218a029
• 作为产物：
  描述：

  2,4,5-三氯苯酚 在 三氯化铝 、 二氯化硫 、 1,2-二氯乙烷 作用下， 生成 3,4,6,3',4',6'-hexachloro-2,2'-sulfanediyl-di-phenol
  参考文献：
  名称：

  2-Hydroxyphenyl Sulfoxides and 2-Hydroxyphenyl Sulfones

  摘要：

  DOI：

  10.1021/ja01218a029

文献信息

• Process for the preparation of halogenated (meth)acrylic esters and poly (meth) arcylates obtained with said (meth)acrylic esters
  申请人：Akzo Nobel N.V.

  公开号：EP0824096A2

  公开（公告）日：1998-02-18

  The present invention is directed to a process for the preparation of (meth)acrylates of halogenated alcohols by direct esterification of said alcohols with (meth)acrylic acid (chloride) wherein at least 2,6-substituted pyridine derivative is used as a polymerization inhibitor at room temperature or lower. Suitable at least 2,6-substituted pyridine derivatives are 2,6-lutidine, 2,4,6-collidine or 2,6-di-tert.butyl-4-methyl pyridine. With the halogenated (meth)acrylate esters prepared with the process according to the invention, very pure homo- and copolymers can be prepared, resulting in polymers having a low optical loss of 0.1 dB/cm or lower at 1300 nm and lower than 0.4 dB/cm at 1550 nm.

  本发明涉及一种通过将卤代醇与（甲基）丙烯酸（氯化物）直接酯化来制备（甲基）丙烯酸酯的方法，其中至少使用一种2,6-取代吡啶衍生物作为聚合抑制剂，温度为室温或更低。适用的至少2,6-取代吡啶衍生物包括2,6-吡啶、2,4,6-考林或2,6-二叔丁基-4-甲基吡啶。 通过根据本发明的方法制备的卤代（甲基）丙烯酸酯，可以制备非常纯净的同聚物和共聚物，从而得到在1300纳米处光学损耗低至0.1 dB/cm或更低，在1550纳米处低于0.4 dB/cm的聚合物。
• Concentrated liquid formulations comprising a microbicidally active ingredient
  申请人：Ciba Specialty Chemicals Holding Inc.

  公开号：EP1201229A1

  公开（公告）日：2002-05-02

  There are described concentrated liquid formulations (b) comprising (b1) 5.1 to 30% by weight of microbicidally active ingredient, (b2) 0 to 80% by weight of sulfonate, (b3) 1 to 60% by weight of a C1-C11monocarboxylic acid or of a C3-C12di- or -polycarboxylic acid; (b4) 0 to 90% by weight of a mono- or dihydric alcohol or mixtures thereof, and water to 100%, it always being necessary for one of the components (b2) or (b4) to be present. The formulations according to the invention are used as microbicidally active ingredient in cosmetic products, household articles or hand disinfectants, as preservatives in household articles and cosmetic products and as disinfectant and decontamination agent for textile fibre materials or the skin and hard surfaces.

  描述如下 浓缩液体制剂(b)，包括 (b1) 5.1%至 30%（按重量计）的微杀菌活性成分、 (b2) 0 至 80%（按重量计）的磺酸盐、 (b3) 1-60%（重量）C1-C11 羧酸或 C3-C12 二羧酸或多羧酸； (b4) 0 至 90%（重量百分比）的一元醇或二元醇或其混合物，以及 水至 100%，(b2)或(b4)中必须有一种成分存在。 本发明的制剂可用作化妆品、家居用品或手部消毒剂中的微杀菌活性成分，家居用品 和化妆品中的防腐剂，以及纺织纤维材料或皮肤和硬表面的消毒剂和去污剂。
• PIPETTE TIPS
  申请人：Biotix, Inc.

  公开号：EP3831489A1

  公开（公告）日：2021-06-09

  The present invention relates to a pipette tip comprising a proximal region and a distal region, wherein the proximal region comprises an exterior surface and an annular flange at the proximal terminus of the proximal region, the proximal region comprises a first set of axially oriented ribs and a second set of axially oriented ribs, the ribs of the first set and the second set are circumferentially spaced and alternately spaced around the exterior surface of the proximal region, and ribs of the first set have a maximum thickness greater than the maximum thickness of ribs of the second set.

  本发明涉及一种移液器吸头，包括一个近端区域和一个远端区域，其中近端区域包括一个外表面和一个位于近端区域近端末端的环形凸缘，近端区域包括第一组轴向定向的肋条和第二组轴向定向的肋条，第一组和第二组肋条在近端区域的外表面周向间隔并交替间隔，第一组肋条的最大厚度大于第二组肋条的最大厚度。
• Small molecule anti-scarring agents
  申请人：UNIVERSITY OF ROCHESTER

  公开号：US10548911B2

  公开（公告）日：2020-02-04

  Disclosed are methods of treating fibrosis in a patient in need thereof that includes administering to the patient an amount of an active agent, as identified herein, that is therapeutically effective to inhibit myofibroblast formation and thereby treat the fibrosis. Also disclosed is a recombinant cell line that includes a recombinant gene that expresses a detectable expression product in a dose-dependent response to TGFβ, as well as methods of identifying a compound that inhibits TGFβ-mediated expression of the detectable expression product.

  公开了治疗有需要的患者纤维化的方法，包括向患者施用一定量的本文所确定的活性剂，该活性剂对抑制肌成纤维细胞的形成从而治疗纤维化具有治疗效果。还公开了一种重组细胞系，该细胞系包括以对TGFβ的剂量依赖性反应表达可检测表达产物的重组基因，以及鉴定抑制TGFβ介导的可检测表达产物表达的化合物的方法。
• Antimicrobial compositions and methods for reducing microbial contamination
  申请人：PolyVation B.V.

  公开号：US11291625B2

  公开（公告）日：2022-04-05

  The invention relates to the fields of microbiology and health care, in particular to means and methods for minimizing the spread of hospital-acquired (HA) infections e.g. between patients and healthcare workers. Provided is an antimicrobial composition comprising an antimicrobial agent, a pharmaceutically acceptable carrier material and a polymer, the polymer being an N-vinyl lactam copolymer, and the composition being capable of forming a slow release antimicrobial film when applied to a skin surface.

  本发明涉及微生物学和医疗保健领域，特别是减少患者与医疗工作者之间医院获得性(HA)感染传播的手段和方法。提供了一种抗菌组合物，包含抗菌剂、药用可接受的载体材料和一种聚合物，该聚合物为N-乙烯基乳酰胺共聚物，且所述组合物在施用于皮肤表面时能够形成一种缓释抗菌膜。 The invention relates to the fields of microbiology and health care, in particular to means and methods for minimizing the spread of hospital-acquired (HA) infections e.g. between patients and healthcare workers. Provided is an antimicrobial composition comprising an antimicrobial agent, a pharmaceutically acceptable carrier material and a polymer, the polymer being an N-vinyl lactam copolymer, and the composition being capable of forming a slow release antimicrobial film when applied to a skin surface.