DL-2-methylamino-butyric acid ethyl ester | 854855-88-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: DL-2-methylamino-butyric acid ethyl ester
• 英文别名: DL-2-Methylamino-buttersaeure-aethylester；α-Methylamino-buttersaeure-aethylester；2-Methylamino-buttersaeure-aethylester；ethyl 2-ethylsarcosine hydrochloride；Ethyl 2-(methylamino)butanoate
• CAS: 854855-88-2
• 化学式: C₇H₁₅NO₂
• mdl: MFCD12151101
• 分子量: 145.202
• InChiKey: ASWJEYHEBZLUCL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.857
• 拓扑面积：
  38.3
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  DL-2-methylamino-butyric acid ethyl ester 在 lithium aluminium tetrahydride 作用下， 以 乙醚 为溶剂， 生成 2-(甲基氨基)丁烷-1-醇
  参考文献：
  名称：

  Kalinina,N.N. et al., Journal of general chemistry of the USSR, 1963, vol. 33, p. 3471 - 3475

  摘要：

  DOI：
• 作为产物：
  描述：

  D,L-N-Methyl-α-aminobuttersaeure 、 乙醇 在 盐酸 作用下， 生成 DL-2-methylamino-butyric acid ethyl ester
  参考文献：
  名称：

  Gansser, Hoppe-Seyler's Zeitschrift fur Physiologische Chemie, 1909, vol. 61, p. 46

  摘要：

  DOI：

文献信息

• Modulators of toll-like receptor 7
  申请人：Chong S. Lee

  公开号：US20080008682A1

  公开（公告）日：2008-01-10

  The present application provides for a compound of Formula I or II: or a pharmaceutically acceptable salt, solvate, and/or ester thereof, compositions containing such compounds, therapeutic methods that include the administration of such compounds, and therapeutic methods that include the administration of such compounds with at least one additional active agent.

  本申请提供了一种公式I或II的化合物： 或其药用可接受的盐、溶剂化物和/或酯，包含此类化合物的组合物，包括施用此类化合物的治疗方法和包括与至少一个附加活性剂施用此类化合物的治疗方法。
• 2-Ethyl-4,6-Dimethyl-Phenyl-Substituted Tetramic Acid Derivatives as Pest Control Agents and/or Herbicides
  申请人：Fischer Reiner

  公开号：US20070225167A1

  公开（公告）日：2007-09-27

  The invention relates to a novel 2-ethyl-4,6-dimethylphenyl-substituted tetramic acid derivatives of the formula (I) in which A, B, D and G are as defined above, to a plurality of processes and intermediates for the preparation and to their use as pesticides and/or herbicides, and also to selective herbicidal compositions comprising firstly 2-ethyl-4,6-dimethylphenyl-substituted tetramic acid derivatives of the formula (I) or (I-a′) and secondly at least one crop plant compatibility-improving compound.

  该发明涉及一种新颖的2-乙基-4,6-二甲基苯基取代的四酰胺酸衍生物，其化学式为(I)，其中A、B、D和G如上所定义，涉及多种用于制备的过程和中间体，以及它们作为杀虫剂和/或除草剂的用途，还涉及选择性除草剂组合物，包括第一是化学式(I)或(I-a′)的2-乙基-4,6-二甲基苯基取代的四酰胺酸衍生物，第二是至少一种作物植物相容性改进化合物。
• NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT
  申请人：Chen James M.

  公开号：US20100104532A1

  公开（公告）日：2010-04-29

  The invention provides unsaturated phosphonates of Formula I or a tautomer or pharmaceutically accepatble salt thereof, as described herein, as well as pharmaceutical compositions comprising the compounds, and therapeutic methods comprising administering the compounds. The compounds have anti-viral properties and are useful for treating viral infections (e.g. HCV) in animals (e.g. humans).

  本发明提供了公式I或其互变异构体或药学上可接受的盐的不饱和膦酸酯，以及包含这些化合物的制药组合物和包括给予这些化合物的治疗方法。这些化合物具有抗病毒性质，适用于治疗动物（如人类）的病毒感染（例如HCV）。
• PHOSPHONATE COMPOUNDS HAVING IMMUNO-MODULATORY ACTIVITY
  申请人：Cannizzaro Carina

  公开号：US20090227543A1

  公开（公告）日：2009-09-10

  The invention is related to phosphonate substituted compounds having immuno-modulatory activity, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

  本发明涉及磷酸酯取代化合物，具有免疫调节活性，含有这种化合物的组合物，以及包括这种化合物的给药的治疗方法，还涉及用于制备这种化合物的有用过程和中间体。
• ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS
  申请人：Cannizzaro Carina

  公开号：US20090247488A1

  公开（公告）日：2009-10-01

  The invention is related to phosphorus substituted anti-inflammatory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

  本发明涉及磷取代的抗炎化合物、含有这种化合物的组合物、包括给药这种化合物的治疗方法，以及用于制备这种化合物的有用过程和中间体。