2-(1-butenyl)aniline | 7137-92-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(1-butenyl)aniline
• 英文别名: (E)-2-(but-1-en-1-yl)aniline；2-[(E)-but-1-enyl]aniline
• CAS: 7137-92-0
• 化学式: C₁₀H₁₃N
• 分子量: 147.22
• InChiKey: BZKLHOLVTZHPBU-ZZXKWVIFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1-(2-nitrophenyl)-1-buten 在 铁粉 作用下， 以 乙醇 、 溶剂黄146 为溶剂， 生成 2-(1-butenyl)aniline
  参考文献：
  名称：

  A Study of the Deoxygenation of Some o-Alkylnitro- and o-Alkylnitrosobenzenes in Triethyl Phosphite¹

  摘要：

  DOI：

  10.1021/ja00968a019

文献信息

• Preparation of amines from olefins using certain transition metal
  申请人：Pennwalt Corporation

  公开号：US04454321A1

  公开（公告）日：1984-06-12

  Aliphatic and aromatic amines are produced by reacting an olefin with either ammonia or a primary or secondary amine in the presence of a catalytic amount of ruthenium or iron compound catalyst. The reaction is carried out in the liquid phase using an inert liquid, a product amine, or one of the reactants as a solvent. The temperatures used are 100.degree. to 250.degree. C. and the pressures are at least autogenous and up to 12,000 psig.

  脂肪族和芳香族胺是通过在存在少量钌或铁化合物催化剂的情况下，将烯烃与氨或一级或二级胺反应而产生的。该反应在液相中进行，使用惰性液体、产物胺或其中一种反应物作为溶剂。使用的温度为100摄氏度至250摄氏度，压力至少为自生的，最高可达12,000磅力/平方英寸。
• The reaction of N-phenylsulfonimidoyl chloride with trimethylsilylethene. A new route to 2-alkenylanilines
  作者：Michael Harmata、Mehmet Kahraman、Darin E. Jones、Neville Pavri、Susan E. Weatherwax

  DOI：10.1016/s0040-4020(98)00591-2

  日期：1998.8

  N-Phenylsulfonimidoyl chloride reacts with trimethylsilylethene in the presence of aluminum chloride to give two product benzothiazines, one of which has been desilylated. The silylated benzothiazine can be deprotonated and alkylated, sometimes with very high diastereocontrol. Upon treatment with fluoride, these silylated benzothiazines undergo desilylation with concomitant cleavage of the carbon-sulfur

  在氯化铝的存在下，N-苯基磺酰亚胺基氯与三甲基甲硅烷基乙烯反应，生成两种苯并噻嗪产品，其中一种已被甲硅烷基化。甲硅烷基化的苯并噻嗪可以被去质子化和烷基化，有时具有非常高的非对映异构控制性。在用氟化物处理后，这些甲硅烷基化的苯并噻嗪进行去甲硅烷基化并伴随碳-硫键的裂解，得到2-烯基亚磺酰苯胺，其可以水解为相应的苯胺。
• Carbonylative N-Heterocyclization via Nitrogen-Directed C–C Bond Activation of Nonactivated Cyclopropanes
  作者：Adam D. J. Calow、David Dailler、John F. Bower

  DOI：10.1021/jacs.2c02921

  日期：2022.6.29

  as directing groups to facilitate regioselective C–C bond activation of nonactivated cyclopropanes. The resulting amino-stabilized rhodacycles undergo carbonylative C–N bond formation en route to challenging seven- and eight-membered lactams. The processes represent rare examples where C–C bond oxidative addition of nonactivated cyclopropanes is exploited in reaction design.

  在 Rh 催化条件下，仲胺和苯胺作为导向基团促进非活化环丙烷的区域选择性 C-C 键活化。由此产生的氨基稳定的罗丹环在形成具有挑战性的七元和八元内酰胺的过程中经历了羰基化 C-N 键的形成。这些过程代表了在反应设计中利用非活化环丙烷的 C-C 键氧化加成的罕见例子。
• Preparation of amines from olefins using certain transition metal catalysts
  申请人：PENNWALT CORPORATION

  公开号：EP0039061A1

  公开（公告）日：1981-11-04

  Aliphatic and aromatic amines are produced by reacting an olefin with either ammonia or a primary or secondary amine in the presence of a catalytic amount of a ruthenium or iron compound catalyst, either dissolved in an inert solvent or in the absence of a solvent, at a temperature of 100 to 250°C and a pressure of from atmospheric to 12,000 psig. Amines have many important commercial uses such as intermediates in the manufacture of rubber products, pharmaceuticals, insecticides, dyestuffs, textile finishing agents, etc.

  脂肪族胺和芳香族胺是通过烯烃与氨或伯胺或仲胺在一定催化量的钌或铁化合物催化剂的存在下，在 100 至 250°C 的温度和大气压至 12,000 psig 的压力下，在溶于惰性溶剂或无溶剂的情况下发生反应而生成的。胺有许多重要的商业用途，如制造橡胶制品、药品、杀虫剂、染料、纺织品整理剂等的中间体。
• Hydrogenation of aromatic amines to produce their ring hydrogenated counterparts
  申请人：AIR PRODUCTS AND CHEMICALS, INC.

  公开号：EP0335272A2

  公开（公告）日：1989-10-04

  This invention relates to an improved hydrogenation process wherein aromatic amines are hydrogenated to their ring hydrogenated counterparts. These aromatic amines are presented by the formulas: wherein R is hydrogen or C₁₋₆ aliphatic, R₁ and R₂ are hydrogen or C₁₋₆ aliphatic, A is C₁₋₄, NH or n is 0-2, x is 1-3 and y is 1 to 2 except the sum of the y groups in Formula I excluding A may be 1.

  本发明涉及一种改进的氢化工艺，在该工艺中，芳香胺被氢化为环氢化对应物。这些芳香胺的结构式如下 其中 R 是氢或 C₁₋₆ 脂肪族，R₁ 和 R₂ 是氢或 C₁₋₆ 脂肪族，A 是 C₁₋₄，NH 或 n 为 0-2，x 为 1-3，y 为 1 至 2，但式 I 中不包括 A 的 y 基团之和可以是 1。