4-(cyclohexylmethyl)pyridine | 34844-98-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 4-(cyclohexylmethyl)pyridine
• 英文别名: 4-Cyclohexylmethyl-pyridin
• CAS: 34844-98-9
• 化学式: C₁₂H₁₇N
• mdl: MFCD06637480
• 分子量: 175.274
• InChiKey: JPEWTYAEMIQXTO-UHFFFAOYSA-N

物化性质

• 沸点：
  266 °C
• 密度：
  0.984±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.583
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  4-(cyclohexylmethyl)pyridine 在 sodium 、 sodium amide 作用下， 以 5,5-dimethyl-1,3-cyclohexadiene 、 氨 、 水 为溶剂， 生成 4,4'-di-(cyclohexylmethyl)-2,2'-bipyridyl
  参考文献：
  名称：

  Substituted 2,2'-bipyridyl compounds and process for preparing same

  摘要：

  一种制备取代2,2'-联吡啶化合物的方法以及制备的几种化合物，该方法包括以下步骤：首先选择一个符合定义的取代吡啶的化合物，然后将过量的该取代吡啶与一定量的氨基钠混合，使得混合物在足够高的温度下形成取代的2,2'-联吡啶，并分离所形成的取代2,2'-联吡啶。新的取代2,2'-联吡啶化合物包括以下化合物：4,4'-二-(5-壬基)-2,2'-联吡啶；4,4'-二-(3-戊基)-2,2'-联吡啶；6,6'-二-(3-戊基)-2,2'-联吡啶；6,6'-二-(5-壬基)-2,2'-联吡啶；4,4'-二-(环己甲基)-2,2'-联吡啶；5,5'-二-(5-壬基)-2,2'-联吡啶；4,4'-二-(3-苯基丙基)-2,2'-联吡啶；4,4'-二-(4-四氢吡喃基)-2,2'-联吡啶；4,4'-二-苄基-2,2'-联吡啶；6,6'-二-异戊基-2,2'-联吡啶；以及4,4'-二-(叔丁基)-2,2'-联吡啶。

  公开号：

  US04177349A1
• 作为产物：
  描述：

  4-苄基吡啶 在 platinum(IV) oxide 、 氢气 、 甲烷 、 三氟乙酸 作用下， 20.0 ℃ 、500.01 kPa 条件下， 以93 %的产率得到4-(cyclohexylmethyl)pyridine
  参考文献：
  名称：

  10.1021/jacs.4c05883

  摘要：

  DOI：

  10.1021/jacs.4c05883

文献信息

• Block copolymers, synthesis and application as dehydrating and desalting of heavy crudes
  申请人：INSTITUTO MEXICANO DEL PETROLEO

  公开号：US10167388B2

  公开（公告）日：2019-01-01

  The present invention is related to formulations consisting of block copolymers α,ω-di-aryl or alkyl sulfonates of poly(ethylene oxide)w-poly(propylene oxide)-poly(ethylene oxide)w of bis-ammonium and block copolymers α,ω-di-amine of poly(ethylene oxide)w-poly(propylene oxide)-poly(ethylene oxide)w, that are effective in the dewatering and desalting crude whose specific gravities are within the range of 14 to 23°API.

  本发明涉及由聚(环氧乙烷)w-聚(环氧丙烷)-聚(环氧乙烷)w 的双铵嵌段共聚物α,ω-二芳基或烷基磺酸盐和聚(环氧乙烷)w-聚(环氧丙烷)-聚(环氧乙烷)w 的嵌段共聚物α,ω-二胺组成的制剂，这些制剂可有效地对比重在 14 至 23°API 范围内的原油进行脱水和脱盐。
• Scale-up process of bifunctionalized triblock copolymers with secondary and tertiary amines, with application in dewatering and desalting of heavy crude oils
  申请人：INSTITUTO MEXICANO DEL PETROLEO

  公开号：US10125226B2

  公开（公告）日：2018-11-13

  A chemical synthesis process is provided for the functionalization of monodispersed triblock copolymer (POEw-POPy-POEw) with secondary or tertiary amines at a semi-industrial level in glass reactors having a capacity between 1 L and 100 L. The process includes two stages where the first stage uses an alkylsulfonyl or arylsulfonyl chloride to obtain better leaving groups, and the second stage is the nucleophilic substitution with secondary or tertiary amines, to obtain the bifunctionalized triblock copolymers. The main advantage for this process is to reduce the quantity of unitary process done in each stage, the optimization of reaction times, and the stoichiometric relationships.

  该工艺包括两个阶段，第一阶段使用烷基磺酰氯或芳基磺酰氯获得更好的离去基团，第二阶段使用仲胺或叔胺进行亲核取代，从而获得双官能化的三嵌段共聚物。这种工艺的主要优点是减少了每个阶段的单一过程，优化了反应时间和化学计量关系。
• Tchitchibabine, Bulletin de la Societe Chimique de France, 1938, vol. <5> 5, p. 429,432
  作者：Tchitchibabine

  DOI：——

  日期：——
• BLOCK COPOLYMERS, SYNTHESIS AND APPLICATION AS DEHYDRATING AND DESALTING OF HEAVY CRUDES
  申请人：INSTITUTO MEXICANO DEL PETROLEO

  公开号：US20140238900A1

  公开（公告）日：2014-08-28

  The present invention is related to formulations consisting by block copolymers α,ω-di-aryl or alkyl sulfonates of poly(ethylene oxide) w -poly(propylene oxide)-poly(ethylene oxide) w of bis-ammonium and block copolymers α,ω-di-amine of poly(ethylene oxide) w -poly(propylene oxide)-poly(ethylene oxide) w , that are effective in the dewatering and desalting crude whose specific gravities are within the range of 14 to 23° API.
• SCALE-UP PROCESS OF BIFUNCTIONALIZED TRIBLOCK COPOLYMERS WITH SECONDARY AND TERTIARY AMINES, WITH APPLICATION IN DEWATERING AND DESALTING OF HEAVY CRUDE OILS
  申请人：INSTITUTO MEXICANO DEL PETROLEO

  公开号：US20140364566A1

  公开（公告）日：2014-12-11

  A chemical synthesis process is provided for the functionalization of monodispersed triblock copolymer (POE w -POP y -POE w ) with secondary or tertiary amines at a semi-industrial level in glass reactors having a capacity between 1 L and 100 L. The process includes two stages where the first stage uses an alkylsulfonyl or arylsulfonyl chloride to obtain better leaving groups, and the second stage is the nucleophilic substitution with secondary or tertiary amines, to obtain the bifunctionalized triblock copolymers. The main advantage for this process is to reduce the quantity of unitary process done in each stage, the optimization of reaction times, and the stoichiometric relationships.