hexyltriphenylphosphonium chloride

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: hexyltriphenylphosphonium chloride
• 英文别名: n-hexyltriphenylphosphonium chloride；Hexyl(triphenyl)phosphanium;chloride
• 化学式: C₂₄H₂₈P*Cl
• 分子量: 382.913
• InChiKey: BBFLFLISKBFBEU-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  2.56
• 重原子数：
  26
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  4-甲基二苯甲酮 、 hexyltriphenylphosphonium chloride 在 正丁基锂 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 生成 (Z)-1-methyl-4-(1-phenylhept-1-enyl)benzene 、 (E)-1-methyl-4-(1-phenylhept-1-enyl)benzene
  参考文献：
  名称：

  铱催化的不对称氢化产生具有弱配位或非配位取代基的手性二芳基甲炔

  摘要：

  含二芳基次甲基的立体中心存在于药物和天然产物中，使得形成这些手性中心的合成方法在工业中很重要。我们已将具有新型 N,P 螯合配体的铱配合物应用于三取代烯烃的不对称氢化，以高转化率和优异的对映选择性（高达 99% ee）形成二芳基次甲基手性中心，适用于广泛的底物。我们的结果支持这样一种假设，即催化剂一个特定区域的空间位阻在立体选择中起着关键作用，因为在前手性碳上几乎没有差异的底物的氢化以高对映选择性发生。结果，即使当前手性碳带有例如苯基和对甲苯基基团时，也能获得出色的立体辨别力。

  DOI：

  10.1021/ja9013375
• 作为产物：
  描述：

  1-氯己烷 、 三苯基膦 反应 2.0h， 以72%的产率得到hexyltriphenylphosphonium chloride
  参考文献：
  名称：

  Synthesis of phosphonium salts under microwave activation — Leaving group and phosphine substituents effects

  摘要：

  微波的特定非纯热效应在苄基亲电试剂与三苯基膦和三丁基膦发生亲核取代反应时得到了证实，根据中性或带电的离去基团。微波辐射显著增强了带电烷基化试剂的反应，特别是在无溶剂条件下。根据过渡态沿反应坐标的位置，结果被解释为微波效应的幅度。关键词：微波辐射，特定效应，磷酸铵盐，离去基团效应。

  DOI：

  10.1139/v04-103

文献信息

• METHOD FOR PRODUCING ARENE COMPOUNDS AND ARENE COMPOUNDS PRODUCED BY THE SAME
  申请人：JSI Silicone Co.

  公开号：US20210188739A1

  公开（公告）日：2021-06-24

  Provided is a method for producing (alkyl)arene compounds represented by Formulae 3-1, 3-2, and 3-3 by the Friedel-Crafts alkylation reaction of alkyl halide compounds and arene compounds using organic phosphine compounds as a catalyst.

  提供了一种通过使用有机膦化合物作为催化剂，通过烷基卤化物化合物和芳烃化合物进行弗里德尔-克拉夫茨烷基化反应生产代表为Formulae 3-1、3-2和3-3的(烷基)芳烃化合物的方法。
• Synthesis of phosphonium salts under microwave activation — Leaving group and phosphine substituents effects
  作者：Ján Cvengros、Stefan Toma、Sylvain Marque、André Loupy

  DOI：10.1139/v04-103

  日期：2004.9.1

  The specific nonpurely thermal effects of microwaves were evidenced according to neutral or charged leaving groups during nucleophilic substitution of benzylic electrophiles with triphenylphosphine and tributylphosphine. Microwave (MW) irradiation considerably enhanced the reactions with charged alkylating agents, especially under solvent-free conditions. Results are interpreted considering the magnitude of MW effects according to the position of the transition state along the reaction coordinates.Key words: microwave irradiation, specific effects, phosphonium salts, leaving group effects.

  微波的特定非纯热效应在苄基亲电试剂与三苯基膦和三丁基膦发生亲核取代反应时得到了证实，根据中性或带电的离去基团。微波辐射显著增强了带电烷基化试剂的反应，特别是在无溶剂条件下。根据过渡态沿反应坐标的位置，结果被解释为微波效应的幅度。关键词：微波辐射，特定效应，磷酸铵盐，离去基团效应。
• PREPARATION OF ORGANOCHLOROSILANES BY THE SILYLATION OF CONJUGATED DIENES WITH TRICHLOROSILANE
  申请人：——

  公开号：US20040063983A1

  公开（公告）日：2004-04-01

  The present invention relates to a process for preparing organosilicon compounds by the silylation of conjugated dienes and more particularly, to the process for preparing organosilicon compounds expressed by the following Formulas 1a and 1b in high yield, comprising the steps of heating trichlorosilane in the presence of quaternary organophosphonium salt catalyst to generate dichlorosilylene (:SiCl 2 ); and silylating the result with linear or cyclic conjugated dienes, 1 wherein R 1 , R 2 , R 3 , R 4 , R 5 and R 6 are independently a hydrogen atom, a C 1 -C 6 alkyl, phenyl group, or two functional groups among R 1 , R 2 , R 3 , R 4 , R 5 and R 6 may be covalently bonded to each other to form a cyclic compound of C 4 -C 8 .

  本发明涉及一种通过硅化共轭二烯制备有机硅化合物的方法，更特别地，涉及一种高产率制备以下1a和1b式表达的有机硅化合物的方法，包括以下步骤：在季铵盐催化剂存在下加热三氯硅烷以生成二氯硅烯（:SiCl2）；并用线性或环状共轭二烯对其进行硅化反应。其中，R1、R2、R3、R4、R5和R6独立地表示氢原子、C1-C6烷基、苯基或R1、R2、R3、R4、R5和R6中的两个功能基团可以共价键合形成C4-C8的环状化合物。
• (ORGANOTHIOMETHYL)CHLOROSILANES AND THEIR PREPARATION METHODS
  申请人：Yoo Ryul Bok

  公开号：US20060211876A1

  公开（公告）日：2006-09-21

  This invention relates to (organothiomethyl)chlorosilanes and methods for their preparation by the dehydrohalogenative Si—C coupling reaction of oranothiomethyl halides with Si—H containing chlorosilanes (hydrosilanes), wherein a mixture of oranothiomethyl halide and hydrosilane is heated in the presence of tertiary amine or organic salts (quaternary organoammonium and organophosphonium halides to give (organothiomethyl)chlorosilanes, which is existing a sulfur atom in alkyl chain, (formula:: R 2 SCH 2 SiCl 2 R 1 ) in good yield, wherein R 1 represents a hydrogen atom, halogen, or C 1 -C 6 alkyl; R 2 is selected from the group consisting of C 1 -C 6 alkyl or an aryl group. Especially, this reaction using organic salt as a catalyst provide better economical matter and yield compared with conventional methods, because only catalytic amount of organic salt is required and the catalyst can be separated from the reaction mixture and recycled easily.

  本发明涉及（有机硫代甲基）氯硅烷及其制备方法，通过有机硫代甲基卤化物与含有Si-H的氯硅烷（氢硅烷）进行去卤素化Si-C偶联反应制备（有机硫代甲基）氯硅烷，其中在热力学条件下，在三级胺或有机盐（季铵和有机磷铵卤化物）的存在下，混合有机硫代甲基卤化物和氢硅烷，可以得到在烷基链中存在硫原子的（式：R2SCH2SiCl2R1）产率良好，其中R1表示氢原子，卤素或C1-C6烷基；R2选自C1-C6烷基或芳基组。特别是，该反应使用有机盐作为催化剂，与传统方法相比，提供更好的经济效益和产率，因为只需要催化剂的量，并且催化剂可以轻松地从反应混合物中分离和回收。
• Diamino compounds and methods for preparing them
  申请人：CHISSO CORPORATION

  公开号：EP0708077A1

  公开（公告）日：1996-04-24

  An object of the invention is to propose diamino compounds expressed by the following general formula (1) which are suitable to obtain a raw material, a polyimide resin, for a liquid crystal aligning film without any image sticking and with a high voltage holding ratio at from a low temperature to a high temperature as well as the preparation thereof: wherein, (a) when R²⁵ being a hydrogen atom and D being , all of R¹¹, R¹², R¹³ and R¹⁴ denote a hydrogen atom, and R²¹, R²², R²³, R²⁴, R³¹, R³², R³³, R³⁴, R⁴¹, R⁴², R⁴³ and R⁴⁴ denote independently each other a hydrogen atom or an alkyl group with 1 to 8 carbon atoms, (b) when R²⁵ being a hydrogen atom and D being , all of R¹¹, R¹², R¹³ and R¹⁴ denote a hydrogen atom, and R²¹ and R³², R²² and R³¹, R²³ and R³⁴, as well as R²⁴ and R³³ are respectively the same atoms or groups and denote independently each other hydrogen atoms or straight-chain or branched alkyl groups with 1 to 8 carbon atoms, and R⁴¹, R⁴², R⁴³, R⁴⁴, R⁵¹, R⁵², R⁵³ and R⁵⁴ denote independently each other a hydrogen atom or an alkyl group with 1 to 8 carbon atoms, (c) when R²⁵ being a hydrogen atom and D being a divalent straight-chain or branched hydrocarbon group with 2 to 30 carbon atoms, R¹¹, R¹², R¹³ and R¹⁴ denote independently a hydrogen atom or a straight-chain or branched alkyl group with 1 to 8 carbon atoms, and R²¹ and R³², R²² and R³¹, R²³ and R³⁴ as well as R²⁴ and R³³ are respectively the same atoms or groups and denote independently each other hydrogen atoms or straight-chain or branched alkyl groups with 1 to 8 carbon atoms, (d) when R²⁵ being a straight-chain or branched alkyl group with 1 to 12 carbon atoms, D denotes a direct bond, an aliphatic group with 1 to 30 carbon atoms, an aromatic group with 6 to 30 carbon atoms, or a divalent hydrocarbon group with 7 to 30 carbon atoms having both an aliphatic group and an aromatic group, R¹¹, R¹², R¹³ and R¹⁴ denote independently a hydrogen atom or a straight-chain or branched alkyl group with 1 to 8 carbon atoms, and R²¹ and R³², R²² and R³¹, R²³ and R³⁴ as well as R²⁴ and R³³ are respectively the same atoms or groups and denote independently each other hydrogen atoms or straight-chain or branched alkyl groups with 1 to 8 carbon atoms.

  本发明的目的是提出由以下通式（1）表示的二氨基化合物及其制备方法，这些化合物适用于获得用于液晶对准膜的原材料--聚酰亚胺树脂，在低温至高温条件下不会产生任何图像粘连，并具有较高的电压保持率： 其中 (a) 当 R²⁵ 是氢原子且 D 是 时，所有R¹¹、R¹²、R¹³和R¹⁴均表示氢原子，而R²¹、R²²、R²³、R²⁴、R³¹、R³²、R³³、R³⁴、R⁴¹、R⁴²、R⁴³和R⁴⁴相互独立地表示氢原子或具有1至8个碳原子的烷基、 (b) 当 R²⁵为氢原子且 D 时，所有 R¹¹、R¹²、R¹³ 和 R¹⁴ 均表示氢原子，R²¹ 和 R³²、R²² 和 R³¹、R²³ 和 R³⁴，以及 R²⁴ 和 R³³ 分别是相同的原子或基团，并各自独立地表示氢原子或具有 1 至 8 个碳原子的直链或支链烷基、和 R⁴¹、R⁴²、R⁴³、R⁴⁴、R⁵¹、R⁵²、R⁵³ 和 R⁵⁴ 相互独立地表示氢原子或具有 1 至 8 个碳原子的烷基、 (c) 当 R²⁵ 为氢原子且 D 为具有 2 至 30 个碳原子的二价直链或支链烃基时，R¹¹、R¹²、R¹³ 和 R¹⁴ 相互独立地表示氢原子或具有 1 至 8 个碳原子的直链或支链烷基、和 R²¹ 和 R³²、R²² 和 R³¹、R²³ 和 R³⁴ 以及 R²⁴ 和 R³³ 分别是相同的原子或基团，并各自独立地表示氢原子或具有 1 至 8 个碳原子的直链或支链烷基、 (d) 当 R²⁵ 是具有 1 至 12 个碳原子的直链或支链烷基时，D 表示直接键、具有 1 至 30 个碳原子的脂肪族基团、具有 6 至 30 个碳原子的芳香族基团或具有 7 至 30 个碳原子且同时具有脂肪族基团和芳香族基团的二价烃基，R¹¹、R¹²、R¹¹、R¹²、R¹³ 和 R¹⁴ 独立地表示氢原子或具有 1 至 8 个碳原子的直链或支链烷基，R²¹ 和 R³²、R²² 和 R³¹、R²³ 和 R³⁴ 以及 R²⁴ 和 R³³ 分别是相同的原子或基团，并独立地表示氢原子或具有 1 至 8 个碳原子的直链或支链烷基。