1-[1-(4-iodomethylphenyl)ethoxy]-2,2,6,6-tetramethylpiperidine | 845728-30-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-[1-(4-iodomethylphenyl)ethoxy]-2,2,6,6-tetramethylpiperidine
• 英文别名: 1-[1-[4-(Iodomethyl)phenyl]ethoxy]-2,2,6,6-tetramethylpiperidine
• CAS: 845728-30-5
• 化学式: C₁₈H₂₈INO
• 分子量: 401.331
• InChiKey: GIPPMWSZMXXXAB-UHFFFAOYSA-N

物化性质

• 熔点：
  72 °C
• 沸点：
  406.3±55.0 °C(Predicted)
• 密度：
  1.33±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  12.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-[1-(4-iodomethylphenyl)ethoxy]-2,2,6,6-tetramethylpiperidine 、 在 potassium carbonate 作用下， 以 丙酮 为溶剂， 反应 48.0h， 以22%的产率得到
  参考文献：
  名称：

  Multi-armed, TEMPO-functionalized unimolecular initiators for starburst dendrimer synthesis via stable free radical polymerization. 1. Tri azo-functionalized unimer

  摘要：

  描述了合成偶氮苯官能化的多臂单分子引发剂或“unimers”，可以使用苯乙烯或苯乙烯衍生物通过TEMPO（2,2,6,6-四甲基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-

  DOI：

  10.1139/v04-107
• 作为产物：
  描述：

  1-(溴甲基)-4-乙基苯 在 二-叔-丁基过氧草酸酯 、 sodium iodide 作用下， 以 丙酮 、 苯 为溶剂， 反应 27.0h， 生成 1-[1-(4-iodomethylphenyl)ethoxy]-2,2,6,6-tetramethylpiperidine
  参考文献：
  名称：

  Multi-armed, TEMPO-functionalized unimolecular initiators for starburst dendrimer synthesis via stable free radical polymerization. 1. Tri azo-functionalized unimer

  摘要：

  描述了合成偶氮苯官能化的多臂单分子引发剂或“unimers”，可以使用苯乙烯或苯乙烯衍生物通过TEMPO（2,2,6,6-四甲基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-

  DOI：

  10.1139/v04-107

文献信息

• Immobilization of Oligostyrene-Prolinol Conjugates into Polystyrene via Electrospinning and Applications of these Fibers in Catalysis
  作者：Joachim Wendorff、Armido Studer、Caren Röben、Michael Stasiak、Birgit Janza、Andreas Greiner

  DOI：10.1055/s-2008-1067146

  日期：2008.7

  This paper reports the synthesis of prolinol-oligostytrene conjugates and their immobilization into a polystyrene matrix by using the electrospinning process. Via this approach fibers with a large surface area (fiber diameter of 1.2 µm) containing the prolinol conjugate are readily obtained. The fibers are shown to be catalytically active in a test Michael reaction. The fibrous catalyst system can readily be removed from the reaction mixture and be reused. However, a decrease of the catalyst activity was noticed upon recycling the fibrous catalyst systems.

  本文报道了以电纺法合成的脯氨醇-低聚苯乙烯共轭物，并将其固定于聚苯乙烯基质中的研究。通过这种方法可以轻松地获得具有较大表面积（纤维直径为1.2微米）且含有脯氨醇共轭物的纤维。这些纤维在迈克尔反应测试中表现出催化活性。该纤维催化剂系统可以轻松地从反应混合物中去除并重复使用。然而，在循环使用纤维催化剂系统时注意到催化活性的下降。
• Reversible switching of substrate activity of poly-N-isopropylacrylamide peptide conjugates
  作者：Kian Molawi、Armido Studer

  DOI：10.1039/b713083j

  日期：——

  The activity of smart polymer peptide conjugates towards chymotrypsin catalyzed hydrolysis was reversibly switched on and off using temperature as the trigger.

  智能聚合物肽偶合物对胰凝乳蛋白酶催化水解的活性，通过温度作为触发器实现了可逆的开关控制。