methyl N-(2-acetamidobenzoyl)anthranilate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: methyl N-(2-acetamidobenzoyl)anthranilate
• 英文别名: Methyl 2-[(2-acetamidobenzoyl)amino]benzoate
• 化学式: C₁₇H₁₆N₂O₄
• 分子量: 312.325
• InChiKey: RBPGYIZQWGMECY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  23
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  84.5
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2-(2-nitrobenzoylamino)benzoic acid methyl ester 在 palladium on activated charcoal 吡啶 、 氢气 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 18.0h， 生成 methyl N-(2-acetamidobenzoyl)anthranilate
  参考文献：
  名称：

  Oligoanthranilamides. Non-Peptide Subunits That Show Formation of Specific Secondary Structure

  摘要：

  A family of novel oligomers based on the anthranilamide nucleus has been prepared and shown to form well-defined secondary structural features. H-1 NMR and X-ray crystallographic techniques have demonstrated that intramolecular hydrogen bonds play a key role in stabilizing both linear sheet and helical conformational forms.

  DOI：

  10.1021/ja9539857

文献信息

• Oligoanthranilamides. Non-Peptide Subunits That Show Formation of Specific Secondary Structure
  作者：Yoshitomo Hamuro、Steven J. Geib、Andrew D. Hamilton

  DOI：10.1021/ja9539857

  日期：1996.1.1

  A family of novel oligomers based on the anthranilamide nucleus has been prepared and shown to form well-defined secondary structural features. H-1 NMR and X-ray crystallographic techniques have demonstrated that intramolecular hydrogen bonds play a key role in stabilizing both linear sheet and helical conformational forms.