四氯丙烷 | 13116-53-5

• 物质功能分类: 化学农药原药 - 除草剂 - 氨基甲酸酯类除草剂
• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氯化物
• 中文名称: 四氯丙烷
• 中文别名: 1,2,2,3-四氯丙烷
• 英文名称: 1,2,2,3-tetrachloropropane
• 英文别名: 1,2,2,3-tetrachloro-propane；1,2,2,3-Tetrachlor-propan；1,2,2,3-Tetrachlor-propane；1,2,2,3-Tetrachloropropan；1,2,2,3-Tetrachlorpropan
• CAS: 13116-53-5
• 化学式: C₃H₄Cl₄
• mdl: MFCD00039362
• 分子量: 181.877
• InChiKey: UDPHJTAYHSSOQB-UHFFFAOYSA-N

物化性质

• 熔点：
  -50.2°C (estimate)
• 沸点：
  87-88/50mm
• 密度：
  1.50
• 溶解度：
  0.00 M
• 蒸汽压力：
  3.05 mmHg
• 保留指数：
  963.9;963

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  7
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

安全信息

• RTECS号：
  TZ7000100
• 海关编码：
  2903199000
• 储存条件：
  室温

SDS

1,2,2,3-Tetrachloropropane Revision number: 5
SAFETY DATA SHEET

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Section 1. IDENTIFICATION
Product name: 1,2,2,3-Tetrachloropropane

Revision number: 5

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Section 2. HAZARDS IDENTIFICATION
GHS classification
PHYSICAL HAZARDS
Category 4
Flammable liquids
HEALTH HAZARDS
Category 4
Acute toxicity (Oral)
Acute toxicity (Dermal) Category 4
Category 4
Acute toxicity (Inhalation)
Skin corrosion/irritation Category 2
Category 2A
Serious eye damage/eye irritation
ENVIRONMENTAL HAZARDS Not classified
GHS label elements, including precautionary statements
Pictograms or hazard symbols
Warning
Signal word
Hazard statements Combustible liquid
Harmful if swallowed, in contact with skin or if inhaled
Causes skin irritation
Causes serious eye irritation
Precautionary statements:
Keep away from flames and hot surfaces.
[Prevention]
Avoid breathing dust/fume/gas/mist/vapours/spray.
Use only outdoors or in a well-ventilated area.
Do not eat, drink or smoke when using this product.
Wash hands thoroughly after handling.
Wear protective gloves and eye/face protection.
1,2,2,3-Tetrachloropropane

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Section 2. HAZARDS IDENTIFICATION
[Response] IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for
breathing. Call a POISON CENTER or doctor/physician if you feel unwell.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
Rinse mouth.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses,
if present and easy to do. Continue rinsing.
If eye irritation persists: Get medical advice/attention.
IF ON SKIN: Gently wash with plenty of soap and water.
If skin irritation occurs: Get medical advice/attention.
Wash contaminated clothing before reuse.
Call a POISON CENTER or doctor/physician if you feel unwell.
[Storage] Store in a well-ventilated place. Keep cool.
[Disposal] Dispose of contents/container through a waste management company authorized by
the local government.

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Section 3. COMPOSITION/INFORMATION ON INGREDIENTS
Substance
Substance/mixture:
Components: 1,2,2,3-Tetrachloropropane
Percent: >95.0%(GC)
CAS Number: 13116-53-5
Chemical Formula: C3H4Cl4

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Section 4. FIRST AID MEASURES
Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Inhalation:
Call a POISON CENTER or doctor/physician if you feel unwell.
Remove/Take off immediately all contaminated clothing. Gently wash with plenty of
Skin contact:
soap and water. If skin irritation or rash occurs: Get medical advice/attention.
Eye contact: Rinse cautiously with water for several minutes. Remove contact lenses, if present
and easy to do. Continue rinsing. If eye irritation persists: Get medical
advice/attention.
Ingestion: Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth.
Protection of first-aiders: A rescuer should wear personal protective equipment, such as rubber gloves and air-
tight goggles.

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Section 5. FIRE-FIGHTING MEASURES
Suitable extinguishing Dry chemical, foam, water spray, carbon dioxide.
media:
Unsuitable extinguishing Solid streams of water
media:
Specific hazards arising Take care as it may decompose upon combustion or in high temperatures to
from the chemical: generate poisonous fume.
Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing
method according to the surrounding situation is used. Uninvolved persons should
evacuate to a safe place. In case of fire in the surroundings: Remove movable
containers if safe to do so.
Special protective When extinguishing fire, be sure to wear personal protective equipment.
equipment for firefighters:

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Section 6. ACCIDENTAL RELEASE MEASURES
Use personal protective equipment. Keep people away from and upwind of spill/leak.
Personal precautions,
protective equipment and Ensure adequate ventilation. Entry to non-involved personnel should be controlled
emergency procedures: around the leakage area by roping off, etc.
Environmental precautions: Prevent product from entering drains.
1,2,2,3-Tetrachloropropane

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Section 6. ACCIDENTAL RELEASE MEASURES
Methods and materials for Absorb spilled material in a suitable absorbent (e.g. rag, dry sand, earth, saw-dust).
containment and cleaning In case of large amount of spillage, contain a spill by bunding. Adhered or collected
up: material should be promptly disposed of, in accordance with appropriate laws and
regulations.
Prevention of secondary Remove all sources of ignition. Fire-extinguishing devices should be prepared in
hazards: case of a fire. Use spark-proof tools and explosion-proof equipment.

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Section 7. HANDLING AND STORAGE
Precautions for safe handling
Technical measures: Handling is performed in a well ventilated place. Wear suitable protective equipment.
Prevent generation of vapour or mist. Keep away from flames and hot surfaces. Take
measures to prevent the build up of electrostatic charge. Use explosion-proof
equipment. Wash hands and face thoroughly after handling.
Use a closed system, ventilation.
Advice on safe handling: Avoid contact with skin, eyes and clothing.
Conditions for safe storage, including any
incompatibilities
Storage conditions: Keep container tightly closed. Store in a cool, dark and well-ventilated place.
Store away from incompatible materials such as oxidizing agents.
Packaging material: Comply with laws.

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Section 8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Engineering controls: Install a closed system or local exhaust as possible so that workers should not be
exposed directly. Also install safety shower and eye bath.
Personal protective equipment
Respiratory protection: Vapor respirator. Follow local and national regulations.
Protective gloves.
Hand protection:
Eye protection: Safety glasses. A face-shield, if the situation requires.
Skin and body protection: Protective clothing. Protective boots, if the situation requires.

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Section 9. PHYSICAL AND CHEMICAL PROPERTIES
Physical state (20°C): Liquid
Form: Clear
Colorless - Slightly pale yellow
Colour:
Odour: No data available
pH: No data available
Melting point/freezing point:No data available
Boiling point/range: 164°C
Flash point: No data available
Flammability or explosive
limits:
Lower: No data available
Upper: No data available
Relative density: 1.50
Solubility(ies):
[Water] No data available
[Other solvents] No data available

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Section 10. STABILITY AND REACTIVITY
Chemical stability: Stable under proper conditions.
Possibility of hazardous No special reactivity has been reported.
reactions:
Open flame
Conditions to avoid:
Incompatible materials: Oxidizing agents
Hazardous decomposition Carbon monoxide, Carbon dioxide, Hydrogen chloride
products:
1,2,2,3-Tetrachloropropane

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Section 11. TOXICOLOGICAL INFORMATION
Acute Toxicity: skn-rbt LD50:>7940 mg/kg
orl-rat LD50:6300 mg/kg
Skin corrosion/irritation: No data available
Serious eye No data available
damage/irritation:
Germ cell mutagenicity: No data available
Carcinogenicity:
IARC = No data available
No data available
NTP =
Reproductive toxicity: No data available
RTECS Number: TZ7000100

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Section 12. ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: 48h LC50:35.43 mg/L (Oryzias latipes)
No data available
Crustacea:
Algae: No data available
Persistence / degradability: 1 % (by BOD), 0 % (by TOC), 4 % (by GC)
Bioaccumulative 12 - 54 (conc. 0.2 mg/L), 22 - 52 (conc. 0.02 mg/L)
potential(BCF):
Mobility in soil
Log Pow: No data available
Soil adsorption (Koc): No data available
Henry's Law No data available
constant(PaM3/mol):

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Section 13. DISPOSAL CONSIDERATIONS
Recycle to process, if possible. Consult your local regional authorities. You may be able to burn in a chemical
incinerator equipped with an afterburner and scrubber system. Observe all federal, state and local regulations when
disposing of the substance.

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Section 14. TRANSPORT INFORMATION
Hazards Class: Does not correspond to the classification standard of the United Nations
UN-No: Not listed

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Section 15. REGULATORY INFORMATION
Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002
and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport,
loading and unloading were prescribed.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

制备方法与用途

化学性质
本品为无色液体，沸点在86～89℃/50 kPa之间，能溶于四氯化碳、氯仿等有机溶剂，但不溶于水。

用途
四氯丙烷是除草剂燕麦敌的中间体。

生产方法
其制备过程是在反应釜中加入四氯化碳和2,3-二氯丙烯，在10～15℃下通入氯气。待通入一定量的氯气后，依次用水洗、Na₂CO₃溶液洗，并再次水洗至中性。随后进行脱溶处理，并在减压条件下蒸馏，收集84～90℃/40～53 kPa的馏分即为成品。

化学反应方程式：ClCH₂CCl=CH₂+Cl₂→ClCH₂CCl₂CH₂Cl

反应信息

• 作为反应物：
  描述：

  四氯丙烷 在 偶氮二异丁酸二甲酯 氯 作用下， 以 四氯化碳 为溶剂， 70.0 ℃ 、1.03 MPa 条件下， 反应 0.1h， 生成 五氯丙烷
  参考文献：
  名称：

  [EN] PROCESS FOR THE PRODUCTION OF CHLORINATED PROPENES
  [FR] PROCÉDÉ POUR LA PRODUCTION DE PROPÈNES CHLORÉS

  摘要：

  提供了生产氯代丙烯的工艺。目前的工艺利用1,2-二氯丙烷，这是氯水合物生产中的副产品，作为低成本的起始原料，单独或与1,2,3-三氯丙烷结合使用。目前的工艺还可以产生无水HCl作为副产品，可以从工艺中去除并用作其他工艺的原料，进一步节省时间和成本。最后，这些工艺有利地在液相中进行，因此与传统的气相工艺相比，提供了额外的节省。

  公开号：

  WO2012166394A1
• 作为产物：
  描述：

  1,2,3-三氯丙烷 在 氯 作用下， 生成 四氯丙烷
  参考文献：
  名称：

  Homolytic chlorination of aliphatic compounds—V

  摘要：

  DOI：

  10.1016/s0040-4020(01)92855-8

文献信息

• [EN] PROCESS FOR THE PRODUCTION OF CHLORINATED PROPENES<br/>[FR] PROCÉDÉ DE PRODUCTION DE PROPÈNES CHLORÉS
  申请人：DOW GLOBAL TECHNOLOGIES LLC

  公开号：WO2013022677A1

  公开（公告）日：2013-02-14

  Processes for the production of chlorinated propenes are provided. The present processes make use of a feedstock comprising 1,2,3-trichloropropane and chlorinates the 1,1,2,3-tetrachloropropane generated by the process prior to a dehydrochlorination step. Production of the less desirable pentachloropropane isomer, 1,1,2,3,3-pentachloropropane, is thus minimized. The present processes provide better reaction yield as compared to conventional processes that require dehydrochlorination of 1,1,2,3-tetrachloropropane prior to chlorinating the same. The present process can also generate anhydrous HCl as a byproduct that can be removed from the process and used as a feedstock for other processes, while limiting the production of waste water, thus providing further time and cost savings.

  提供了生产氯代丙烯的工艺。目前的工艺利用包含1,2,3-三氯丙烷的原料，并在去氢氯化步骤之前氯化由该过程产生的1,1,2,3-四氯丙烷。因此，生产较不理想的五氯丙烷异构体1,1,2,3,3-五氯丙烷被最小化。与需要在氯化相同物质之前对1,1,2,3-四氯丙烷进行去氢氯化的传统工艺相比，目前的工艺提供了更好的反应产率。目前的工艺还可以生成无水HCl作为副产品，可以从工艺中去除并用作其他工艺的原料，同时限制废水的产生，从而提供进一步的时间和成本节约。
• Compositions comprising 2,3,3,3-tetrafluoropropene, 1,1,2,3-tetra-chloropropene, 2-chloro-3,3,3-trifluoropropene, or 2-chloro-1,1,1,2-tetrafluoropropane
  申请人：THE CHEMOURS COMPANY FC, LLC

  公开号：US09308408B2

  公开（公告）日：2016-04-12

  The present disclosure relates to compositions comprising 2,3,3,3-tetrafluoropropene that may be useful as heat transfer compositions, aerosol propellants, foaming agents, blowing agents, solvents, cleaning agents, carrier fluids, displacement drying agents, buffing abrasion agents, polymerization media, expansion agents for polyolefins and polyurethane, gaseous dielectrics, extinguishing agents, and fire suppression agents in liquid or gaseous form. Additionally, the present disclosure relates to compositions comprising 1,1,2,3-tetrachloropropene, 2-chloro-3,3,3-trifluoropropene, or 2-chloro-1,1,1,2-tetrafluoropropane, which may be useful in processes to produce 2,3,3,3-tetrafluoropropene.

  本公开涉及包含2,3,3,3-四氟丙烯的组合物，可能用作传热组合物、气雾剂推进剂、发泡剂、吹膜剂、溶剂、清洁剂、载体流体、置换干燥剂、抛光磨损剂、聚合介质、聚烯烃和聚氨酯的膨胀剂、气体绝缘体、灭火剂，以及液体或气态形式的灭火剂。此外，本公开涉及包含1,1,2,3-四氯丙烯、2-氯-3,3,3-三氟丙烯或2-氯-1,1,1,2-四氟丙烷的组合物，可能在生产2,3,3,3-四氟丙烯的过程中有用。
• PROCESSES FOR PREPARING 1,1,2,3-TETRACHLOROPROPENE
  申请人：Merkel Daniel C.

  公开号：US20090030249A1

  公开（公告）日：2009-01-29

  Provided is a continuous process for preparing 1,1,2,3-tetrachloro-1-propene having the steps of catalytically dehydrochlorinating CH 2 ClCCl 2 CH 2 Cl in the gas phase to produce CHCl═CClCH 2 Cl; chlorinating the CHCl═CClCH 2 Cl to form CHCl 2 CCl 2 CH 2 Cl; and catalytically dehydrochlorinating the CHCl 2 CCl 2 CH 2 Cl in the gas phase to form CCl 2 ═CClCH 2 Cl.

  提供了一种制备1,1,2,3-四氯-1-丙烯的连续过程，包括以下步骤：在气相中催化脱氯化CH2ClCCl2CH2Cl，产生CHCl═CClCH2Cl；将CHCl═CClCH2Cl氯化成CHCl2CCl2CH2Cl；在气相中催化脱氯化CHCl2CCl2CH2Cl，形成CCl2═CClCH2Cl。
• [EN] PROCESS FOR THE PRODUCTION OF CHLORINATED PROPANES AND/OR PROPENES<br/>[FR] PROCÉDÉ POUR LA PRODUCTION DE PROPANES ET/OU PROPÈNES CHLORÉS
  申请人：DOW GLOBAL TECHNOLOGIES LLC

  公开号：WO2013074394A1

  公开（公告）日：2013-05-23

  Processes for the production of chlorinated propanes and/or propenes are provided. The present processes make use of methylacetylene, a by-product in the production of ethylene and/or propylene, as a low cost starting material, alone or in combination with propadiene, propene and/or propane. In the latter embodiments, the processes may also be utilized to provide a substantially pure stream of propane.

  提供了生产氯代丙烷和/或丙烯的工艺。本工艺利用甲基乙炔作为低成本的起始材料，甲基乙炔是生产乙烯和/或丙烯的副产物，可以单独使用或与丙二烯、丙烯和/或丙烷结合使用。在后者的实施例中，该工艺还可用于提供一个基本纯净的丙烷流。
• [EN] SULFURYL CHLORIDE AS CHLORINATING AGENT<br/>[FR] CHLORURE DE SULFURYLE COMME AGENT CHLORANT
  申请人：DOW GLOBAL TECHNOLOGIES LLC

  公开号：WO2013095699A1

  公开（公告）日：2013-06-27

  The use of sulfuryl chloride, either alone or in combination with chlorine, as a chlorinating agent is disclosed.

  本发明公开了磺酰氯的使用，无论是单独使用还是与氯结合使用作为氯化剂。

表征谱图