4-硝基-1-[4-[4-硝基-2-(三氟甲基)苯氧基]苯氧基]-2-(三氟甲基)苯 | 302781-16-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 4-硝基-1-[4-[4-硝基-2-(三氟甲基)苯氧基]苯氧基]-2-(三氟甲基)苯
• 英文名称: 1,4'-bis(4-nitrotrifluoromethylphenoxy)benzene
• 英文别名: 1,4-bis(4-nitro-2-trifluoromethylphenoxy)benzene；Benzene, 1,4-bis[4-nitro-2-(trifluoromethyl)phenoxy]-；4-nitro-1-[4-[4-nitro-2-(trifluoromethyl)phenoxy]phenoxy]-2-(trifluoromethyl)benzene
• CAS: 302781-16-4
• 化学式: C₂₀H₁₀F₆N₂O₆
• 分子量: 488.3
• InChiKey: JTCDAMOOKOQQGZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  34
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  110
• 氢给体数：
  0
• 氢受体数：
  12

反应信息

• 作为反应物：
  描述：

  4-硝基-1-[4-[4-硝基-2-(三氟甲基)苯氧基]苯氧基]-2-(三氟甲基)苯 在 palladium on activated charcoal 、 一水合肼 作用下， 生成 4,4’-[1,4-苯基双(氧)]双[3-(三氟甲基)苯胺]
  参考文献：
  名称：

  Novel ‘naked-eye’ Bis-Schiff base fluorescent chemosensors for sensitive detection of Zn2+ and bio-imaging in living cells

  摘要：

  Novel chemosensors based on excited state intramolecular proton transfer chemosensors (F1, F3, F5) and reference dyes (F2, F4, F6) are presented in this work. Target dyes Fl, F3 and F5 display high selectivity and sensitivity toward Zn2+ in solvents (such as EtOH, EtOH/PBS buffer) in the presence of competitive ions (K+, Na+, Ni2+, Pb2+, Mn2+, Mg2+, Hg2+, Cu2+,Cd2+, Cr3+, Fe3+). Sensing property for Zn2+ was studied by UV-Visible, fluorescence spectrophotometric analyses and Job's plot analyses. F1, F3 and F5 for Zn2+ detection revealed extremely low detection limit (67.2 nM), high anti-interference ability, and the immediate response. Furthermore, inverted fluorescence microscopy imaging experiment were also investigated, the results demonstrated that the probes have well cell membrane permeability and hypotoxicity. Simultaneously, due to the ability to adapt a wider range of pH, the probes could also image Zn2+ in live cells with remarkable fluorescence variation and provide a new method to visualize monitoring in live cells. (C) 2020 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2020.131108
• 作为产物：
  描述：

  2-氯-5-硝基三氟甲苯 、 对苯二酚 在 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 24.0h， 以64.9%的产率得到4-硝基-1-[4-[4-硝基-2-(三氟甲基)苯氧基]苯氧基]-2-(三氟甲基)苯
  参考文献：
  名称：

  Xu, Wenzong; Zhang, Yingying; Hu, Yuan, Asian Journal of Chemistry, 2012, vol. 24, # 9, p. 3976 - 3980

  摘要：

  DOI：

文献信息

• 新規芳香族ジアミンおよびポリイミド
  申请人：——

  公开号：JP2000297067A

  公开（公告）日：2000-10-24

  (57)【要約】\n【課題】 高い耐熱性と優れた成形加工性を有し、さらに、低吸水性、溶剤溶解性、高い透明性、低複屈折性を有する、光学用途に適したポリイミド、及び、該ポリイミドの原料モノマーである新規芳香族ジアミンを提供する。\n【解決手段】 化学式（１）\nで表される芳香族ジアミン。 化学式（２）\nで表される繰り返し構造単位を有する芳香族ポリイミド。

  (57) [摘要] Јn[主题] 提供一种适用于光学应用的聚酰亚胺，该聚酰亚胺具有高耐热性和优异的成型加工性，同时还具有低吸水性、溶剂溶解性、高透明度和低双折射，以及一种新的芳香族二胺，该二胺是所述聚酰亚胺的原料单体。\由化学式（1）Јn 表示的芳香族二胺。 具有化学式 (2) Јn 所代表的重复结构单元的芳香族聚酰亚胺。
• Jin, Yan; Ding, Yinhao; Hou, Xichao, Journal of the Indian Chemical Society, 2020, vol. 97, # 1, p. 101 - 107
  作者：Jin, Yan、Ding, Yinhao、Hou, Xichao、Dong, Jingjing、Lu, Jianqiang、Feng, Baicheng

  DOI：——

  日期：——
• CN117263805
  申请人：——

  公开号：——

  公开（公告）日：——
• Novel ‘naked-eye’ Bis-Schiff base fluorescent chemosensors for sensitive detection of Zn2+ and bio-imaging in living cells
  作者：Xinchao Wang、Ge Ding、Yuanke Duan、Min Wang、Guangshi Zhu、Xiujuan Li、Yanfen Zhang、Xiaozhuan Qin

  DOI：10.1016/j.tet.2020.131108

  日期：2020.4

  Novel chemosensors based on excited state intramolecular proton transfer chemosensors (F1, F3, F5) and reference dyes (F2, F4, F6) are presented in this work. Target dyes Fl, F3 and F5 display high selectivity and sensitivity toward Zn2+ in solvents (such as EtOH, EtOH/PBS buffer) in the presence of competitive ions (K+, Na+, Ni2+, Pb2+, Mn2+, Mg2+, Hg2+, Cu2+,Cd2+, Cr3+, Fe3+). Sensing property for Zn2+ was studied by UV-Visible, fluorescence spectrophotometric analyses and Job's plot analyses. F1, F3 and F5 for Zn2+ detection revealed extremely low detection limit (67.2 nM), high anti-interference ability, and the immediate response. Furthermore, inverted fluorescence microscopy imaging experiment were also investigated, the results demonstrated that the probes have well cell membrane permeability and hypotoxicity. Simultaneously, due to the ability to adapt a wider range of pH, the probes could also image Zn2+ in live cells with remarkable fluorescence variation and provide a new method to visualize monitoring in live cells. (C) 2020 Elsevier Ltd. All rights reserved.
• Xu, Wenzong; Zhang, Yingying; Hu, Yuan, Asian Journal of Chemistry, 2012, vol. 24, # 9, p. 3976 - 3980
  作者：Xu, Wenzong、Zhang, Yingying、Hu, Yuan、Lu, Bo、Cai, Tongming

  DOI：——

  日期：——