乙酸山嵛基酯 | 822-26-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 乙酸山嵛基酯
• 英文名称: 1-docosanol acetate
• 英文别名: 1-docosyl acetate；docosyl acetate；acetic acid docosyl ester；Essigsaeure-docosylester；1-docosanol, acetate；Docosanolyl-1-acetat
• CAS: 822-26-4
• 化学式: C₂₄H₄₈O₂
• 分子量: 368.644
• InChiKey: AWYRDXDPCQRJHE-UHFFFAOYSA-N

物化性质

• 保留指数：
  2594

计算性质

• 辛醇/水分配系数(LogP)：
  11
• 重原子数：
  26
• 可旋转键数：
  22
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.958
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

制备方法与用途

乙酸苯酯是一种生物化学试剂，可用作生物材料或有机化合物，在生命科学相关研究中发挥重要作用。

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 acetic acid ester 作用下， 生成 乙酸山嵛基酯
  参考文献：
  名称：

  Stoll; Rouve, Helvetica Chimica Acta, 1944, vol. 27, p. 957

  摘要：

  DOI：

文献信息

• Zn(ClO4)2·6H2O as a Powerful Catalyst for a Practical Acylation of Alcohols with Acid Anhydrides
  作者：Giuseppe Bartoli、Marcella Bosco、Renato Dalpozzo、Enrico Marcantoni、Massimo Massaccesi、Letizia Sambri

  DOI：10.1002/ejoc.200300458

  日期：2003.12

  new protocol for the acylation of alcohols with anhydrides in the presence of Zn(ClO4)2·6H2O as the catalyst is reported. The activity of Zn(ClO4)2·6H2O has been proven to be superior to that exerted by dry Mg(ClO4)2 and by metal triflates. Its efficiency allows reactions between poorly reactive substrates, such as sterically hindered tertiary alcohols and aromatic anhydrides. All of the reactions

  报道了一种在 Zn(ClO4)2·6H2O 作为催化剂的情况下用酸酐酰化醇的新方案。已证明 Zn( )2·6H2O 的活性优于干燥的 Mg( )2 和金属三氟甲磺酸盐。其效率允许反应性较差的底物（例如位阻叔醇和芳香酸酐）之间发生反应。所有反应均以1:1.05的醇/酸酐比进行。从实用和经济的角度来看，这些条件非常方便，因为它们避免了试剂的浪费并允许简单的后处理程序。Zn( )2·6H2O 的催化作用对酸酐的活化非常特殊，以至于在酯化过程中对酸敏感的官能团和起始材料的立体化学构型保持不变。在所有情况下，酰化产物都是以纯形式定量获得的。(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)
• Bartoli, Giuseppe; Bosco, Marcella; Dalpozzo, Renato, Synlett, 2003, # 1, p. 39 - 42
  作者：Bartoli, Giuseppe、Bosco, Marcella、Dalpozzo, Renato、Marcantoni, Enrico、Massaccesi, Massimo、Rinaldi, Samuele、Sambri, Letizia

  DOI：——

  日期：——
• The Thermal and Dielectric Properties of Crystalline Long‐Chain Acetates
  作者：R. J. Meakins、Joan W. Mulley

  DOI：10.1063/1.1698720

  日期：1953.11

  This investigation deals with the normal long-chain acetates with 18, 20, 24, and 28 carbon atoms. When crystallized from the melt, these compounds first give the transparent α-phase which gradually changes to the white, opaque β-phase on standing or on cooling below a certain temperature. It is found that the acetates in the α-phase all give large dielectric absorption, whereas, in the β-phase the absorption is small, or, in some cases, negligible. Of the long-chain compounds so far investigated, the acetates in the α-phase are unique in giving two absorption regions which appear to be the result of the rotational transitions of complete molecules. The maxima for the two regions are separated by about 7 decades in frequency. Measurements of the lower frequency absorption at various temperatures show that the associated energy barrier is very large compared with previous values for compounds of similar chain-length. To explain these results it is suggested that a molecule rotating in the crystal lattice of a long-chain compound possesses four positions of equilibrium instead of two, as previously proposed. In addition to the two absorption regions mentioned above, the long-chain acetates in the α-phase give further absorption at still higher frequencies, which is probably caused by independent orientation of the polar groups near the ends of the molecular chains.
• STEPHANOU, EURIPIDES G., FRESENIUS J. ANAL. CHEM., 339,(1991) N0, C. 780-784
  作者：STEPHANOU, EURIPIDES G.

  DOI：——

  日期：——

表征谱图