5-ethylcoumarin

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: 5-ethylcoumarin
• 英文别名: 5-Ethylcumarine；5-ethylchromen-2-one
• 化学式: C₁₁H₁₀O₂
• 分子量: 174.199
• InChiKey: GWPBVRLCNHPTEW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  苹果酸 、 3-乙基苯酚 在 硫酸 作用下， 反应 1.0h， 生成 7-ethylcoumarin 、 5-ethylcoumarin
  参考文献：
  名称：

  Osborne, Alan G.; Andrews, Steven J.; Mower, Rachel, Journal of Chemical Research, Miniprint, 2003, # 3, p. 319 - 338

  摘要：

  DOI：

文献信息

• A process for producing octahydrocoumarins and same as a product of such process
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0757989A1

  公开（公告）日：1997-02-12

  The present invention involves the production of octahydrocoumarins from coumarins and/or 3,4-dihydrocoumarins in good yields by a simple process which can be industrially carried out by reducing coumarins and/or 3,4-dihydrocoumarins to octahydrocoumarins with hydrogen in the presence of an alcohol and a ruthenium catalyst, and optionally heating resultant 3-(2-hydroxycyclohexyl) propionate contained in the reduction reaction mixture to conduct cyclization/dealcoholization and convert same to octahydrocoumarins.

  本发明涉及以香豆素和/或 3,4-二氢香豆素为原料生产八氢香豆素，产率高，工艺简单、4-二氢香豆素在醇和钌催化剂存在下用氢气还原成八氢香豆素，并可选择加热还原反应混合物中所含的 3-(2-羟基环己基)丙酸酯，以进行环化/脱醇反应并将其转化成八氢香豆素。
• Single phase liquid mixture of benzophenone and mixture of at least two other normally solid perfumery substances and perfumery uses thereof
  申请人：INTERNATIONAL FLAVORS & FRAGRANCES INC.

  公开号：EP0994176A2

  公开（公告）日：2000-04-19

  Described is a single phase liquid mixture of benzophenone and a mixture of at least two other normally solid perfumery substances which mixture contains from about 25% up to about 60% by weight of benzophenone and from about 60% down to about 25% by weight of a mixture of normally crystalline perfumery ingredients, each of which has a melting point of between about 35°C and about 120°C at about 1 atmosphere pressure, containing at least two substances of the following classes: (i) coumarin derivatives; (ii) vanillin derivatives; (iii) resorcylic acid derivatives; (iv) methylene dioxybenzene derivatives; (v) trichloro-α-phenylethyl esters; (vi) polycyclic musks; (vii) aryl alkanoic acids; and (viii) p-oxoalkylphenols and uses of such mixtures in augmenting or enhancing the aroma of perfume compositions, colognes and perfumed articles, including but not limited to solid or liquid anionic, cationic, nonionic or zwitterionic detergents, fabric softener compositions, fabric softener articles, hair preparations, cosmetic powders and perfumed polymers.

  所述的是二苯甲酮和至少两种其它正常固态香水物质的单相液态混合物，该混合物含有约 25% 至约 60% （按重量计）的二苯甲酮和约 60% 至约 25% （按重量计）的正常结晶香水成分混合物，每种成分在约 1 个大气压下的熔点在约 35°C 至约 120°C 之间，其中至少含有两种以下类别的物质： (i) 香豆素衍生物 (ii) 香兰素衍生物 (iii) 间苯二甲酸衍生物 (iv) 亚甲基二氧基苯衍生物 (v) 三氯-α-苯乙酯 (vi) 多环麝香 (vii) 芳基烷酸；以及 (viii) 对氧代烷基酚 以及这些混合物在增加或提高香水组合物、古龙水和加香物品的香气方面的用途，包括但不限于固体或液体阴离子、阳离子、非离子或齐聚物洗涤剂、织物柔软剂组合物、织物柔软剂物品、头发制剂、化妆品粉末和加香聚合物。
• Modified nucleotides and uses thereof
  申请人：Singular Genomics Systems, Inc.

  公开号：US11174281B1

  公开（公告）日：2021-11-16

  Disclosed herein, inter alia, are compounds, modified nucleotides, compositions, and methods of using the same.

  本文特别公开了化合物、修饰核苷酸、组合物以及使用它们的方法。
• METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW
  申请人：Bridgestone Corporation

  公开号：US20140187725A1

  公开（公告）日：2014-07-03

  A method for preparing a coupled polymer, the method comprising the steps of: (i) polymerizing monomer to form a reactive polymer, and (ii) reacting the reactive polymer with coumarin or a substituted coumarin compound.
• US5639893A
  申请人：——

  公开号：US5639893A

  公开（公告）日：1997-06-17