1,5-diphenoxy-3-oxapentane | 622-87-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1,5-diphenoxy-3-oxapentane
• 英文别名: β,β'-Bis(phenoxyethyl)ether；Diethylene glycol diphenyl ether；diethylene glycol phenyl ether；di-phenyl diethylene glycol；β.β'-Diphenoxy-diaethylaether；1,1'-[oxybis(2,1-ethanediyloxy)]bis-benzene；Bis-(2-phenoxy-aethyl)-aether；bis-(2-phenoxy-ethyl)-ether；phenyl monoglycol ether；2-Phenoxyethanol Ether；monophenylglycol ether；Bis(2-phenoxyethyl)ether；2-(2-phenoxyethoxy)ethoxybenzene
• CAS: 622-87-7
• 化学式: C₁₆H₁₈O₃
• 分子量: 258.317
• InChiKey: PICKZMGDVSSGSC-UHFFFAOYSA-N

物化性质

• 沸点：
  167-170 °C(Press: 0.2 Torr)
• 密度：
  1.086±0.06 g/cm3(Predicted)
• 熔点：
  65-70 °C

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  19
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1,5-diphenoxy-3-oxapentane 在 Rh/Al₂O₃ 氢气 作用下， 以 甲醇 为溶剂， 40.0 ℃ 、4.14 MPa 条件下， 反应 8.0h， 以88%的产率得到diethyleneglycol dicyclohexyl ether
  参考文献：
  名称：

  Buchanan, G. W.; Moghimi, A.; Reynolds, V. M., Canadian Journal of Chemistry, 1995, vol. 73, # 4, p. 566 - 572

  摘要：

  DOI：
• 作为产物：
  描述：

  苯酚 在 氢氧化钾 、 sodium hydroxide 、 水 作用下， 生成 1,5-diphenoxy-3-oxapentane
  参考文献：
  名称：

  Wohl; Berthold, Chemische Berichte, 1910, vol. 43, p. 2179

  摘要：

  DOI：

文献信息

• Process for the preparation of cyclic esters and method for purification of the same
  申请人：——

  公开号：US20030191326A1

  公开（公告）日：2003-10-09

  The present invention provides a process for production of a cyclic ester by depolymerization of an aliphatic polyester. In the process, a mixture containing the aliphatic polyester and a specific polyalkylene glycol ether, which has a boiling point of 230-450° C. and a molecular weight of 150-450, is heated under normal or reduced pressure to a temperature at which depolymerization of the aliphatic polyester takes place. Then, a substantially homogeneous solution phase, consisting of the melt phase of the aliphatic polyester and the liquid phase of the polyalkylene glycol ether, is formed. Heating of the solution phase is continued to form the cyclic ester by depolymerization and distil out the cyclic ester together with the polyalkylene glycol ether, and then the cyclic ester is recovered from the distillate. The present invention also provides a process for purification of a crude cyclic ester by use of the specific polyalkylene glycol ether described above.

  本发明提供了一种通过脂肪族聚酯的降解来生产环酯的方法。在该过程中，将含有脂肪族聚酯和具有沸点在230-450°C和分子量在150-450之间的特定聚烷基乙二醇醚的混合物，在常压或减压下加热至脂肪族聚酯发生降解的温度。然后，形成由脂肪族聚酯的熔融相和聚烷基乙二醇醚的液相组成的基本均相溶液相。继续加热溶液相以通过降解形成环酯并与聚烷基乙二醇醚一起蒸馏出环酯，然后从馏出物中回收环酯。本发明还提供了一种利用上述特定聚烷基乙二醇醚对粗环酯进行纯化的方法。
• PROCESS FOR THE PRODUCTION OF DIARYL CARBONATES
  申请人：General Electric Company

  公开号：US20020077497A1

  公开（公告）日：2002-06-20

  A process for catalytic production of diaryl carbonates by oxidative carbonylation of aromatic hydroxy compounds with carbon monoxide and oxygen achieves water removal during reaction by a process comprising the steps of: removing a liquid stream from an oxidative carbonylation reaction mixture in a reaction vessel, subjecting the liquid stream to reduced pressure, and returning at least a portion of dried liquid stream to the reaction vessel. Typical catalyst systems for oxidative carbonylation contain (A) at least one Group 8, 9, or 10 metal having an atomic number of at least 44 or a compound thereof; (B) at least one alkali metal salt; (C) at least one metal co-catalyst; (D) at least one activating organic solvent; and (E) optionally, at least one base.

  一种通过芳香羟基化合物与一氧化碳和氧气进行氧化羰基化反应催化生产二芳醚碳酸酯的方法，通过以下步骤实现反应过程中的水去除：从反应容器中的氧化羰基化反应混合物中移除液体流，将液体流经受减压处理，然后至少将干燥后的液体流的一部分返回至反应容器。典型的氧化羰基化催化剂体系包括（A）至少一种原子序数至少为44的8、9或10族金属或其化合物；（B）至少一种碱金属盐；（C）至少一种金属共催化剂；（D）至少一种活化有机溶剂；以及（E）可选地至少一种碱。
• Compositions containing esters of aromatic alkoxylated alcohols and fatty carboxylic acids
  申请人：——

  公开号：US20030161792A1

  公开（公告）日：2003-08-28

  A personal care or cosmetic product composition that includes from about 0.1% to about 99% of at least one ester of alkoxylated aromatic alcohol and fatty carboxylic acid, and from about 0.1% to 60% of at least one functional ingredient is provided. The functional ingredients in the composition may include active ingredients and additional ingredients. Especially suitable active ingredients are sunscreen active ingredients and antiperspirant active ingredients. Preferred compositions are sunscreen product formulations and antiperspirant products. In one preferred embodiment, the composition further includes at least one cyclomethicone compound present in the amount of from about 1% to 99% by weight of the composition. A method of improving the protection of human or animal skin or hair from radiation and a method of improving the protection of human or animal skin or hair from perspiration are also provided.

  提供一种个人护理或化妆品组合物，包括约0.1%至约99%的至少一种烷氧基芳香醇和脂肪羧酸酯，以及约0.1%至60%的至少一种功能性成分。组合物中的功能性成分可能包括活性成分和额外成分。特别适用的活性成分包括防晒活性成分和止汗活性成分。首选的组合物是防晒产品配方和止汗产品。在一个首选实施例中，该组合物还包括至少一种环硅烷化合物，其占组合物重量的约1%至99%。还提供了一种改善人类或动物皮肤或毛发免受辐射的保护的方法，以及一种改善人类或动物皮肤或毛发免受汗水侵害的方法。
• METHOD FOR PRODUCING a-HYDROXYCARBOXYLIC ACID DIMERIC CYCLIC ESTER
  申请人：Kureha Corporation

  公开号：US20190330175A1

  公开（公告）日：2019-10-31

  Provided is a method for producing a high purity α-hydroxycarboxylic acid dimeric cyclic ester while heavy-component formation from an α-hydroxycarboxylic acid oligomer is suppressed. An α-hydroxycarboxylic acid dimeric cyclic ester is obtained by performing a depolymerization reaction in the coexistence of an inorganic acid or an inorganic acid salt or a mixture thereof; and an organophosphorus compound.

  提供了一种制备高纯度α-羟基羧酸二聚环酯的方法，同时抑制从α-羟基羧酸寡聚体中形成重组分。通过在无机酸或无机酸盐或二者混合物的共存下进行解聚反应，并加入有机磷化合物，可以得到α-羟基羧酸二聚环酯。
• METHOD FOR PRODUCING CYCLIC ESTER
  申请人：Kureha Corporation

  公开号：US20200392102A1

  公开（公告）日：2020-12-17

  In a method for producing a cyclic ester according to an embodiment of the present invention, a mixture (I) containing an aliphatic polyester, a specific polyalkylene glycol diether, and a sulfonic acid compound as a thermal stabilizer is prepared and heated in predetermined conditions to obtain a mixture (II) in a state of solution. Furthermore, heating of the mixture (II) is continued to distill, together with the polyalkylene glycol diether, a cyclic ester formed by the depolymerization reaction, and thus a distillate (III) is obtained. The cyclic ester is recovered from the distillate (III). At this time, a specific solubilizing agent is added to at least one of the mixture (I) or (II). In this production method, the sulfonic acid compound as the thermal stabilizer is contained in the mixtures (I) and (II) and the distillate (III).

  根据本发明实施例的一种制备环酯的方法中，制备含有脂肪族聚酯、特定聚烷基醚二醇和磺酸化合物作为热稳定剂的混合物(I)，并在预定条件下加热，得到处于溶液状态的混合物(II)。此外，继续加热混合物(II)以蒸馏，与聚烷基醚二醇一起蒸馏出由去聚合反应形成的环酯，从而得到馏出物(III)。从馏出物(III)中回收环酯。此时，在混合物(I)或(II)中至少添加一种特定的溶解剂。在此生产方法中，磺酸化合物作为热稳定剂被包含在混合物(I)、(II)和馏出物(III)中。

表征谱图