1,4-二(2-氢过氧基丙-2-基)苯 | 3159-98-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 1,4-二(2-氢过氧基丙-2-基)苯
• 中文别名: 二环[2.2.1]庚烷,1,3-二氯-
• 英文名称: p-diisopropylbenzene dihydroperoxide
• 英文别名: 1,4-Bis-(α-hydroperoxy-isopropyl)-benzol；p-Diisopropyl-benzol-dihydroperoxid；p-Bis(hydroperoxyisopropyl)benzene；1,4-bis(2-hydroperoxypropan-2-yl)benzene
• CAS: 3159-98-6
• 化学式: C₁₂H₁₈O₄
• 分子量: 226.273
• InChiKey: REGMWDPZVFOJLY-UHFFFAOYSA-N

物化性质

• 熔点：
  141.0 °C

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  58.9
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1,4-二(2-氢过氧基丙-2-基)苯 在 磷酸 作用下， 生成 对苯二酚
  参考文献：
  名称：

  Preparation of hydroquinone

  摘要：

  公开号：

  US02748172A1
• 作为产物：
  描述：

  1,4-二异丙基苯 在 sodium hydroxide 、 过氧化氢二异丙苯 、 氧气 作用下， 生成 1,4-二(2-氢过氧基丙-2-基)苯
  参考文献：
  名称：

  Oxidation of aromatic hydrocarbons

  摘要：

  公开号：

  US02548435A1
• 作为试剂：
  描述：

  溴苯 、 1,4-二(丁烷-2-基)苯 在 sodium hydroxide 、 air 、 1,4-二(2-氢过氧基丙-2-基)苯 作用下， 生成 1-(4-sec-butyl-phenyl)-1-methyl-propyl hydroperoxide 、 1,4-bis-(1-hydroperoxy-1-methyl-propyl)-benzene
  参考文献：
  名称：

  Autoxidation of hydrocarbons

  摘要：

  公开号：

  US02820064A1

文献信息

• Synthesis of New Primary-Tertiary Alkyl Bisperoxides by Reaction of Tertiary Hydroperoxides with Bromoalkanesin a PTC System
  作者：Jan Zawadiak、Mirosław Danch、Mariola Pigulla

  DOI：10.1007/s007060170069

  日期：2001.7

   Syntheses of novel primary-tertiary bisperoxides were carried out under phase transfer catalysis conditions. The bisperoxides were obtained in good yields, the reaction times not exceeding four hours.

   在相转移催化条件下进行新型伯叔双氧化物的合成。以高收率获得双过氧化物，反应时间不超过4小时。
• Process and apparatus for the preparation of phenols
  申请人：MITSUI PETROCHEMICAL INDUSTRIES, LTD.

  公开号：EP0021848A1

  公开（公告）日：1981-01-07

  A process for the preparation of phenols comprises reacting in a reaction vessel (1) an a-hydroxyalkyl-substituted aromatic compound and/or an α,β-unsaturated alkyl-substituted aromatic compound with hydrogen peroxide in the presence of an acid catalyst, in which hydrogen peroxide is diluted with a diluent, especially acetone, so that the volume is at least 10 times the original volume, and the diluted hydrogen peroxide is supplied in separate portions to at least two parts of a reaction vessel or is scattered into the reaction vessel (1) by sprinkling. According to a preferred embodiment, the diluted hydrogen peroxide is continuously supplied to the gas phase in the reaction vessel from a scattering device (12) which is similar to but separate from a scattering device (2) for supplying the starting aromatic compound, in particular a product formed by oxidizing an isopropyl aromatic compound with molecular oxygen. According to this process, the efficiency of utilization of hydrogen peroxide is increased and a phenol of high quality can be obtained safely and in a high yield.

  制备苯酚的工艺包括在酸催化剂存在下，在反应容器(1)中使 a-羟基烷基取代的芳香化合物和/或 α，β-不饱和烷基取代的芳香化合物与过氧化氢反应、其中过氧化氢用稀释剂，特别是丙酮稀释，使其体积至少为原体积的 10 倍，稀释过的过氧化氢分别供给反应容器的至少两个部分，或通过洒水撒入反应容器 (1)。根据一个优选的实施方案，稀释的过氧化氢从一个散射装置（12）持续供应到反应容器中的气相中，该装置类似于供应起始芳香族化合物的散射装置（2），但又与之分开，起始芳香族化合物特别是异丙基芳香族化合物与分子氧氧化形成的产物。 根据这种工艺，可以提高过氧化氢的利用效率，安全、高产地获得高质量的苯酚。
• Stable composition for the determination of peroxidatively active substances
  申请人：MILES INC.

  公开号：EP0230229A2

  公开（公告）日：1987-07-29

  A stable test device for the determination of a peroxidatively active substance comprising a carrier containing 1,4-diisopropylbenzene dihydroperoxide and a benzidine indicator in a molar ratio of from 0.9 to 3.0. The composition can be incorporated with a carrier matrix with a ferric chelate to provide ascorbate resistance, important in a urine test for occult blood. The test device is stable under storage and heat stress and can be used to prepare a multitest strip containing a glucose test based on a peroxidase/potassium iodide indicator system.

  一种用于测定过氧化活性物质的稳定检测装置，由含有 1,4-二异丙苯二过氧化氢和联苯胺指示剂的载体组成，摩尔比为 0.9 至 3.0。 该组合物可与含有铁螯合物的载体基质结合，以提供抗坏血酸抗性，这在尿液隐血检测中非常重要。 该检测装置在储存和热应力条件下稳定，可用于制备含有基于过氧化物酶/碘化钾指示剂系统的葡萄糖检测试纸的多重检测条。
• Oxidation process of aromatic compounds
  申请人：KUREHA KAGAKU KOGYO KABUSHIKI KAISHA

  公开号：EP0267759A2

  公开（公告）日：1988-05-18

  An aromatic compound selected from benzene and biphenyl compounds containing at least one isopropyl group is oxidized to convert at least one of the at least one isopropyl group into a 2-hydroxy-2-propyl group. The oxidation of the aromatic compound is effected with molecular oxygen in the presence of an aqueous alkali solution in an oxidative reaction vessel made of nickel at parts thereof where the vessel comes into contact with a reaction mixture. In particular, the above process suppresses the formation of byproducts and permits long-term oxidation on an industrial scale.

  一种芳香族化合物，选自苯和含有至少一个异丙基的联苯化合物，通过氧化将至少一个异丙基转化为 2-羟基-2-丙基。 芳香族化合物的氧化是在镍制成的氧化反应容器中，在该容器与反应混合物接触的部位，在碱水溶液存在下，用分子氧进行的。 特别是，上述工艺可抑制副产物的形成，并允许在工业规模上进行长期氧化。
• Process for producing polyhydroperoxy aromatic compound
  申请人：MITSUBISHI PETROCHEMICAL CO., LTD.

  公开号：EP0482573A2

  公开（公告）日：1992-04-29

  A process for producing a polyhydroperoxy aromatic compound by oxidation of an aromatic hydrocarbon, e.g., 4,4'-diisopropylbiphenyl and 4,4'-diisopropylnaphthalene, with molecular oxygen is disclosed, in which the oxidation is carried out in the presence of a metal ion selected from cobalt, nickel, zinc and lead ions. Even in using a reaction apparatus made of an iron-containing metal generally employed in industry, a high conversion of secondary alkyl groups can be reached, and the desired polyhydroperoxy aromatic compound can be obtained in a high yield.

  本发明公开了一种通过芳香烃（如 4,4'-二异丙基联苯和 4,4'-二异丙基萘）与分子氧的氧化反应生产聚氢过氧芳香化合物的工艺，其中氧化反应是在选自钴、镍、锌和铅离子的金属离子存在下进行的。即使使用工业中普遍使用的含铁金属制成的反应装置，也能达到较高的仲烷基转化率，并能以较高的产率获得所需的多氢过氧芳香化合物。