苯并烯氟菌唑 | 1072957-71-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 四氢化萘
• 中文名称: 苯并烯氟菌唑
• 英文名称: benzovindiflupyr
• 英文别名: N-[9-(dichloromethylene)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide；N-[9-(dichloromethylen)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-3-(difluoromethyl)-1-methyl-1H-pyrazol-4-carboxamide；3-difluoromethyl-1-methyl-1 H-pyrazole-4-carboxylic acid (9-dichloromethylene-1,2,3,4-tetrahydro-1,4-methano-naphthalen-5-yl)-amide；N-[11-(dichloromethylidene)-3-tricyclo[6.2.1.02,7]undeca-2(7),3,5-trienyl]-3-(difluoromethyl)-1-methylpyrazole-4-carboxamide
• CAS: 1072957-71-1
• 化学式: C₁₈H₁₅Cl₂F₂N₃O
• 分子量: 398.239
• InChiKey: CCCGEKHKTPTUHJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  26
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  46.9
• 氢给体数：
  1
• 氢受体数：
  4

安全信息

• 储存条件：
  20°C

制备方法与用途

Benzovindiflupyr 是一种琥珀酸脱氢酶抑制剂（SDHI），对宋氏菌具有高度活性，可用于研究菌核病和茎腐病。

反应信息

• 作为产物：
  描述：

  6,6-dichlorofulvene 在 aluminum (III) chloride 、 rhodium contaminated with carbon 吡啶 、 甲醇 、 sodium tetrahydroborate 、 硫酸 、 盐酸羟胺 、 氢气 、 三甲基乙酰氯 、 三乙胺 作用下， 以 四氢呋喃 、 1,4-二氧六环 、 乙醇 、 水 为溶剂， 反应 20.67h， 生成 苯并烯氟菌唑
  参考文献：
  名称：

  PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES

  摘要：

  这项发明涉及一种制备3-二氟甲基-1-甲基-1H-吡唑-4-羧酸(9-二氯甲亚甲基-1,2,3,4-四氢-1,4-甲基-萘-5-基)-酰胺的过程。

  公开号：

  US20120136162A1

文献信息

• N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES
  申请人：BAYER CROPSCIENCE AG

  公开号：US20140315898A1

  公开（公告）日：2014-10-23

  The present invention relates to novel N-arylamide-substituted trifluoroethyl sulfide derivatives of the formula (I) in which X 1 , X 2 , X 3 , X 4 , R 1 , R 2 , R 3 , n have the meanings given in the description—to their use as acaricides and insecticides for controlling animal pests and to processes and intermediates for their preparation

  本发明涉及公式（I）中的新型N-芳酰胺取代三氟乙基硫醚衍生物，其中X1、X2、X3、X4、R1、R2、R3、n的含义如描述所示—它们作为杀螨剂和杀虫剂用于控制动物害虫，并涉及其制备的过程和中间体。
• PRODUCTION METHOD FOR PYRAZOLE-4-CARBOXAMIDE DERIVATIVE
  申请人：JAPAN FINECHEM COMPANY, INC.

  公开号：US20200181091A1

  公开（公告）日：2020-06-11

  The present invention relates to a method of producing a pyrazole-4-carboxamide derivative including subjecting a pyrazole-4-carboxylic acid ester and an amine to an aminolysis reaction in a solvent in the presence of a base, provided that the reaction is completed without removing a by-produced alcohol or phenol outside the system. An industrial production method of a pyrazole-4-carboxamide derivative which is useful as an agricultural fungicide, simply and in high yield and high purity as compared with the conventional method, is provided.

  本发明涉及一种生产吡唑-4-甲酰胺衍生物的方法，包括将吡唑-4-羧酸酯和胺在溶剂中在碱的存在下进行醇解反应，条件是反应完成后不将系统中产生的醇或酚去除。提供了一种作为农业杀菌剂的吡唑-4-甲酰胺衍生物的工业生产方法，与常规方法相比，该方法简单且以高收率和高纯度进行。
• [EN] DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS<br/>[FR] DÉRIVÉS DE DIHYDROFURANE EN TANT QUE COMPOSÉS INSECTICIDES
  申请人：SYNGENTA PARTICIPATIONS AG

  公开号：WO2013026726A1

  公开（公告）日：2013-02-28

  The present invention provides compounds of formula I wherein Q is Q1 or Q2; A1, A2, A3 and A4 are independently of each other C-H, C-R7, or nitrogen; R1 is C1-C8haloalkyl; R2 is aryl or aryl substituted by one to five R11, or heteroaryl or heteroaryl substituted by one to five R11; and R3, R4, R5, R6 and R7 are as defined in the claims. The invention also provides methods of controlling insects, acarines, nematodes or molluscs which methods comprise applying to a pest, to a locus of a pest, or to a plant susceptible to attack by a pest an insecticidally, acaricidally, nematicidally or molluscicidally effective amount of a compound of formula (I).

  本发明提供了式I的化合物，其中Q是Q1或Q2；A1、A2、A3和A4分别独立地为C-H、C-R7或氮；R1为C1-C8卤代烷基；R2为芳基或被1至5个R11取代的芳基，或者为杂环芳基或被1至5个R11取代的杂环芳基；以及R3、R4、R5、R6和R7如权利要求中所定义的。该发明还提供了控制昆虫、螨虫、线虫或软体动物的方法，该方法包括向害虫、害虫的生境或易受害虫侵害的植物施加式(I)的化合物的杀虫、杀螨、杀线虫或杀软体动物的有效量。
• [EN] INSECTICIDAL COMPOUNDS<br/>[FR] COMPOSÉS INSECTICIDES
  申请人：SYNGENTA PARTICIPATIONS AG

  公开号：WO2012163959A1

  公开（公告）日：2012-12-06

  The present invention provides compounds of formula (I): wherein A1, A2, A3 and A4 are independently of one another C-H, C-R5, or nitrogen; B1--B2--B3--B4 is -CH2-C=N-CH2-, -CH2-N-CH2-CH2-, -CH2-C=CH-0- or -CH=C-CH2-0-; G1 is oxygen or sulfur; L is a single bond or C1-C8alkylene; R1 is hydrogen, C1-C8alkyl, C1-C8alkylcarbonyl-, C1-C8alkoxy, C2-C8alkenyl, C2-C8alkynyl, C1-C8alkoxy- C1-C8alkyl, aryl or aryl substituted by one to three R6, or R1 is heterocyclyl or heterocyclyl substituted by one to three R6 or C1-C8alkoxycarbonyl-; R2 is hydrogen, C1-C8haloalkyl or C1-C8alkyl; R3 is C1-C8haloalkyl; R4 is aryl or aryl substituted by one to three R6, or R4 is heterocyclyl or heterocyclyl substituted by one to three R6; Y1 is CR7R8, C=O or C=S; Y2, Y3 and Y4 are independently CR7R8, C=0, C=S, N-R9, O, S, SO or SO2; wherein at least two adjacent ring atoms in the ring formed by Y1, Y2, Y3 and Y4 are heteroatoms; each R7 and R8 is independently hydrogen, halogen, C1-C8alkyl, or C1-C8haloalkyl; and R5, R6, R7, R8 and R9 are as defined in the claims. The invention also relates to processes and intermediates for preparing these compounds, to insecticidal, acaricidal, nematicidal and molluscicidal compositions comprising these compounds and to methods of using these compounds to control insect, acarine, nematode and mollusc pests.

  本发明提供了以下式（I）的化合物：其中A1、A2、A3和A4彼此独立地为C-H、C-R5或氮；B1--B2--B3--B4为-CH2-C=N-CH2-、-CH2-N-CH2-CH2-、-CH2-C=CH-0-或-CH=C-CH2-0-；G1为氧或硫；L为单键或C1-C8烷基；R1为氢、C1-C8烷基、C1-C8烷基羰基、C1-C8烷氧基、C2-C8烯基、C2-C8炔基、C1-C8烷氧基-C1-C8烷基、芳基或被1至3个R6取代的芳基，或R1为杂环烷基或被1至3个R6或C1-C8烷氧羰基取代的杂环烷基；R2为氢、C1-C8卤代烷基或C1-C8烷基；R3为C1-C8卤代烷基；R4为芳基或被1至3个R6取代的芳基，或R4为杂环烷基或被1至3个R6取代的杂环烷基；Y1为CR7R8、C=O或C=S；Y2、Y3和Y4独立地为CR7R8、C=0、C=S、N-R9、O、S、SO或SO2；其中由Y1、Y2、Y3和Y4形成的环中至少有两个相邻的环原子为杂原子；每个R7和R8独立地为氢、卤素、C1-C8烷基或C1-C8卤代烷基；而R5、R6、R7、R8和R9如权利要求中所定义。本发明还涉及制备这些化合物的过程和中间体，包括这些化合物的杀虫剂、杀螨剂、杀线虫剂和杀软体动物剂组合物，以及使用这些化合物控制昆虫、螨类、线虫和软体动物害虫的方法。
• [EN] HALOGEN SUBSTITUTED DIKETONES, PYRAZOLE COMPOUNDS AND PROCESSES FOR THE MANUFACTURE OF PYRAZOLE COMPOUNDS<br/>[FR] DICÉTONES SUBSTITUÉES PAR UN HALOGÈNE, COMPOSÉS DE PYRAZOLE ET LEURS PROCÉDÉS DE PRODUCTION
  申请人：SOLVAY

  公开号：WO2017129759A1

  公开（公告）日：2017-08-03

  The present invention concerns new halogen substituted diketone compounds, new pyrazole compounds, processes for the manufacture of pyrazole compounds and processes for the manufacture of agrochemical or pharmaceutical compounds.

  本发明涉及新的卤代二酮化合物、新的吡唑化合物、制造吡唑化合物的方法以及制造农用化学品或药物化合物的方法。