CXCR4 INHIBITING CARRIERS FOR NUCLEIC ACID DELIVERY
申请人:Wayne State University
公开号:US20140243397A1
公开(公告)日:2014-08-28
The present invention generally relates to carriers including polymers and lipids that comprise a CXCR4 inhibiting moiety. More specifically, these carriers are biodegradable and can be bioreducible polymers that comprise a CXCR4 inhibiting moiety. These carriers can be suitable for delivery of nucleic acids to cells. These carriers and pharmaceutical compositions can be used to treat various conditions including cancers and inflammation conditions.