2-[[6-[5-(2-Hydroxyethoxymethyl)pyridin-2-yl]pyridin-3-yl]methoxy]ethanol | 942907-78-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2-[[6-[5-(2-Hydroxyethoxymethyl)pyridin-2-yl]pyridin-3-yl]methoxy]ethanol
• 英文别名: 2-[[6-[5-(2-hydroxyethoxymethyl)pyridin-2-yl]pyridin-3-yl]methoxy]ethanol
• CAS: 942907-78-0
• 化学式: C₁₆H₂₀N₂O₄
• 分子量: 304.346
• InChiKey: FORZJKFSXVXBDF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  22
• 可旋转键数：
  9
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  84.7
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  2-[[6-[5-(2-Hydroxyethoxymethyl)pyridin-2-yl]pyridin-3-yl]methoxy]ethanol 、 二乙基磷乙酸 在 吡啶 、 氯化亚砜 作用下， 以 二氯甲烷 为溶剂， 反应 12.0h， 以96%的产率得到2-[[6-[5-[2-[2-[Diethoxy(oxido)phosphaniumyl]acetyl]oxyethoxymethyl]pyridin-2-yl]pyridin-3-yl]methoxy]ethyl 2-[diethoxy(oxido)phosphaniumyl]acetate
  参考文献：
  名称：

  Facile synthesis of new fullerene–Ru(bpy)3 dyads bearing phosphonate groups for hybrid organic–inorganic materials

  摘要：

  Fullerene reacted with mono- and diphosphonate-bearing bipyridines by way of Bingel-type reactions to give adducts which were easily transformed in the corresponding dyads by forming Ru(bpy)3 complexes. Electrochemical measurements and the observation of heavy quenching of the Ru(bpy)3 luminescence manifested strong interactions between the active moieties. Attempts to include the dyads into inorganic matrices derived from zirconium phosphate are reported. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2007.03.100
• 作为产物：
  描述：

  5 5'-二甲基-2,2'-二吡啶 在 N-溴代丁二酰亚胺(NBS) 、 sodium 、 过氧化苯甲酰 作用下， 以 四氯化碳 为溶剂， 反应 14.0h， 生成 2-[[6-[5-(2-Hydroxyethoxymethyl)pyridin-2-yl]pyridin-3-yl]methoxy]ethanol
  参考文献：
  名称：

  Facile synthesis of new fullerene–Ru(bpy)3 dyads bearing phosphonate groups for hybrid organic–inorganic materials

  摘要：

  Fullerene reacted with mono- and diphosphonate-bearing bipyridines by way of Bingel-type reactions to give adducts which were easily transformed in the corresponding dyads by forming Ru(bpy)3 complexes. Electrochemical measurements and the observation of heavy quenching of the Ru(bpy)3 luminescence manifested strong interactions between the active moieties. Attempts to include the dyads into inorganic matrices derived from zirconium phosphate are reported. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2007.03.100

文献信息

• Facile synthesis of new fullerene–Ru(bpy)3 dyads bearing phosphonate groups for hybrid organic–inorganic materials
  作者：Ernesto Brunet、Marina Alonso、Ma Carmen Quintana、Olga Juanes、Juan-Carlos Rodríguez-Ubis

  DOI：10.1016/j.tetlet.2007.03.100

  日期：2007.5

  Fullerene reacted with mono- and diphosphonate-bearing bipyridines by way of Bingel-type reactions to give adducts which were easily transformed in the corresponding dyads by forming Ru(bpy)3 complexes. Electrochemical measurements and the observation of heavy quenching of the Ru(bpy)3 luminescence manifested strong interactions between the active moieties. Attempts to include the dyads into inorganic matrices derived from zirconium phosphate are reported. (c) 2007 Elsevier Ltd. All rights reserved.