3,4,5-Trihydroxyphthalic acid | 82297-95-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3,4,5-Trihydroxyphthalic acid
• CAS: 82297-95-8
• 化学式: C₈H₆O₇
• 分子量: 214.131
• InChiKey: YVTWZIZBFIANKG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  135
• 氢给体数：
  5
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  3,4,5-Trihydroxyphthalic acid 以 xylene 为溶剂， 生成 3,4,5-Trihydroxyphthalic anhydride
  参考文献：
  名称：

  Malhotra, S.; Misra, K., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1982, vol. 21, # 2, p. 107 - 108

  摘要：

  DOI：
• 作为产物：
  描述：

  2-formyl-3,4,5-trihydroxybenzoic acid 在 potassium permanganate 作用下， 以 丙酮 为溶剂， 生成 3,4,5-Trihydroxyphthalic acid
  参考文献：
  名称：

  Malhotra, S.; Misra, K., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1982, vol. 21, # 2, p. 107 - 108

  摘要：

  DOI：

文献信息

• Regioselective<i>para</i>-Carboxylation of Catechols with a Prenylated Flavin Dependent Decarboxylase
  作者：Stefan E. Payer、Stephen A. Marshall、Natalie Bärland、Xiang Sheng、Tamara Reiter、Andela Dordic、Georg Steinkellner、Christiane Wuensch、Susann Kaltwasser、Karl Fisher、Stephen E. J. Rigby、Peter Macheroux、Janet Vonck、Karl Gruber、Kurt Faber、Fahmi Himo、David Leys、Tea Pavkov-Keller、Silvia M. Glueck

  DOI：10.1002/anie.201708091

  日期：2017.10.23

  prFMN-dependent enzyme that is capable of directly carboxylating aromatic catechol substrates under ambient conditions. A reaction mechanism for the reversible decarboxylation involving an intermediate with a single covalent bond between a quinoid adduct and cofactor is proposed, which is distinct from the mechanism of prFMN-associated 1,3-dipolar cycloadditions in related enzymes.

  利用二氧化碳作为有机合成的碳源满足了化学品生产更加可持续性的迫切需求。在此，我们报告了酶催化儿茶酚的对位羧化，使用属于 UbiD 酶家族的 3,4-二羟基苯甲酸脱羧酶 (AroY)。晶体结构和随附的溶液数据证实，AroY 利用最近发现的异戊二烯化 FMN (prFMN) 辅因子，并且需要氧化成熟才能形成具有催化能力的 prFMNiminium 物质。本研究报告了 prFMN 依赖性酶的体外重建和激活，该酶能够在环境条件下直接羧化芳香族儿茶酚底物。提出了一种涉及醌型加合物和辅因子之间具有单共价键的中间体的可逆脱羧反应机制，该机制不同于相关酶中与 prFMN 相关的 1,3-偶极环加成机制。
• Method of preventing polymer-scale formation
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP0320227A2

  公开（公告）日：1989-06-14

  A method of preventing polymer scales from sticking in a polymerization vessel during the polymerization of a monomer having an ethylenically double bond, wherein said polymerization is carried out in a polymerization vessel of which the inner wall and other parts with which said monomer comes into contact during polymerization are previously first coated with (a) a coating solution comprising a cationic dye and the resulting coating is then coated with (b) a coating solution comprising at least one component selected from the group consisting of anionic polymeric compounds, amphoteric polymeric compounds and hydroxyl group-containing organic compounds. Polymer scale formation can be effectively prevented.

  一种在具有乙烯双键的单体聚合过程中防止聚合物鳞片粘附在聚合容器中的方法，其中所述聚合在聚合容器中进行，聚合容器的内壁和在聚合过程中与所述单体接触的其他部分之前先涂有(a)由阳离子染料组成的涂层溶液，然后在所得涂层上涂有(b)由至少一种从阴离子聚合物化合物、两性聚合物化合物和含羟基有机化合物组成的组中选出的组分组成的涂层溶液。可有效防止聚合物结垢。
• Lubricant composition
  申请人：KYODO YUSHI CO., LTD.

  公开号：US20020193263A1

  公开（公告）日：2002-12-19

  A lubricant composition comprises (1) at least one member selected from the group consisting of carboxylic acid compounds each obtained by the addition of an oxyalkylene group to a hydroxyl group of a hydroxy carboxylic acid and alkali metal salts and amine salts thereof; and (2) at least one base oil selected from the group consisting of alkyl benzene, normal paraffin, isoparaffin and &agr;-olefin. The lubricant composition is highly resistant to putrefaction when it is used as a metal-processing oil composition and shows excellent cutting characteristics in the metal-processing, which requires an extremely high lubricating action, such as form-rolling tap and deep hole boring. Moreover, the composition makes operations such as metal-processing operations easy since the liquid obtained by diluting it with water is transparent or translucent.

  一种润滑油组合物包括：(1) 至少一种选自羧酸化合物组的成员，每种羧酸化合物都是通过在羟基羧酸的羟基上添加一个氧亚烷基和碱金属盐及其胺盐而得到的；(2) 至少一种选自烷基苯、普通石蜡、异链烷烃和&agr;-烯烃组的基础油。该润滑油组合物在用作金属加工油组合物时具有很强的抗腐化性，在需要极高润滑作用的金属加工（如轧制丝锥和深孔镗孔）中表现出优异的切削特性。此外，由于用水稀释后得到的液体是透明或半透明的，因此这种组合物可以使金属加工等操作变得简单。
• Anhydride stabilization
  申请人：Huntsman Petrochemical Corporation

  公开号：US20030083522A1

  公开（公告）日：2003-05-01

  Disclosed herein are compositions comprising organic anhydrides having a reduced tendency to discolor with time, even when held at elevated temperatures for extended times. The compositions are produced by mixing at least one acid halide and various derivatives of hydroxy carboxylic acids with an anhydride to form a homogenous solution. Also disclosed is a process for preparing the compositions.

  本文所公开的是由有机酸酐组成的组合物，即使在高温下长时间保存，其随时间变色的趋势也会降低。这些组合物是通过将至少一种酸卤化物和羟基羧酸的各种衍生物与酸酐混合形成均质溶液而制得的。此外，还公开了制备这些组合物的工艺。
• ANHYDRIDE STABILIZATION
  申请人：HUNTSMAN PETROCHEMICAL CORPORATION

  公开号：EP1144354A1

  公开（公告）日：2001-10-17