6-O-lauryl sorbitol | 22522-14-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 6-O-lauryl sorbitol
• 英文别名: Sorbit-monolaurat；Sorbityl 1-laurate；[(2R,3R,4R,5S)-2,3,4,5,6-pentahydroxyhexyl] dodecanoate
• CAS: 22522-14-1；34311-73-4
• 化学式: C₁₈H₃₆O₇
• 分子量: 364.48
• InChiKey: HYZDYRHKPFPODK-BURFUSLBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  25
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  127
• 氢给体数：
  5
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  月桂酸 、 山梨醇 在 lipase Candida sp. 99–125 作用下， 以 水 、 叔丁醇 为溶剂， 生成 6-O-lauryl sorbitol 、 sorbitan mono-laurate
  参考文献：
  名称：

  Enzymatic production and functional characterization of d-sorbitol monoesters with various fatty acids

  摘要：

  Sugar fatty acid esters are surfactants that are widely used in food, cosmetics, and pharmaceutical industries. In this study, enzymatic production of o-sorbitol monoesters with various fatty acids (C10-C18) was assessed. Reactions were performed in tert-butanol at 40 degrees C, catalyzed by Candida sp. 99-125 lipase. Dissolution of the substrates was found to be the limiting step of the reaction, and hence preheating was performed to increase the solubility of D-sorbitol. Thus, the yield of D-sorbitol palmitate was increased from 734 to 31.6 mM. The results demonstrated that the specific lipase preferred long-chain fatty acids. The surface-active properties. of the products were also determined. (C) 2015 Published by Elsevier B.V.

  DOI：

  10.1016/j.catcom.2015.09.010

文献信息

• Enzymatic production and functional characterization of d-sorbitol monoesters with various fatty acids
  作者：Xin Zhang、Kaili Nie、Yongli Zheng、Fang Wang、Li Deng、Tianwei Tan

  DOI：10.1016/j.catcom.2015.09.010

  日期：2015.12

  Sugar fatty acid esters are surfactants that are widely used in food, cosmetics, and pharmaceutical industries. In this study, enzymatic production of o-sorbitol monoesters with various fatty acids (C10-C18) was assessed. Reactions were performed in tert-butanol at 40 degrees C, catalyzed by Candida sp. 99-125 lipase. Dissolution of the substrates was found to be the limiting step of the reaction, and hence preheating was performed to increase the solubility of D-sorbitol. Thus, the yield of D-sorbitol palmitate was increased from 734 to 31.6 mM. The results demonstrated that the specific lipase preferred long-chain fatty acids. The surface-active properties. of the products were also determined. (C) 2015 Published by Elsevier B.V.