邻苯二甲酸苄基甲酯 | 1225-85-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 邻苯二甲酸苄基甲酯
• 英文名称: Benzyl methyl phthalate
• 英文别名: 2-MeO2CC6H4CO2Bn；Phthalic acid, benzyl methyl ester；2-O-benzyl 1-O-methyl benzene-1,2-dicarboxylate
• CAS: 1225-85-0
• 化学式: C₁₆H₁₄O₄
• 分子量: 270.285
• InChiKey: AKKMBTJVARDPMB-UHFFFAOYSA-N

物化性质

• 熔点：
  54-55 °C
• 沸点：
  160 °C(Press: 0.8 Torr)
• 密度：
  1.196±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  20
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

安全信息

• 海关编码：
  2917349000

反应信息

• 作为反应物：
  描述：

  邻苯二甲酸苄基甲酯 在 甲醇 、 sodium tetrahydroborate 、 nickel(II) chloride hexahydrate 作用下， 反应 0.17h， 以83%的产率得到邻苯二甲酸单甲酯
  参考文献：
  名称：

  Rapid Chemoselective Deprotection of Benzyl Esters by Nickel Boride

  摘要：

  多种酸的苄酯在室温下使用镍硼化物处理甲醇溶液时，可以进行化学选择性裂解，以高产率得到母体羧酸。其他保护功能团，如甲酯、乙酯、叔丁酯、三苯甲酯、苄醚、叔丁醚以及N-苄基酰胺，在这些条件下均不受影响。

  DOI：

  10.1055/s-0028-1087982
• 作为产物：
  描述：

  乙酸苄酯 在 四氢吡咯 、 bromomagnesium diisopropylamide 、 4 A molecular sieve 、 碳酸氢钠 、 三乙胺 作用下， 以 乙醚 、 二氯甲烷 、 水 、 N,N-二甲基甲酰胺 为溶剂， 反应 85.0h， 生成 邻苯二甲酸苄基甲酯
  参考文献：
  名称：

  Benzyl Methyl (S)-2-(p-Tolylsulfinyl)maleate, an Efficient Dienophile in Asymmetric Diels-Alder Reactions

  摘要：

  The enantiomerically pure dienophile 3 [1-benzyl 4-methyl (S)-(p-tolylsulfinyl)maleate] was readily prepared in a three-step sequence from benzyl acetate and (-)-(S)-menthyl p-toluenesulfinate (46% overall yield). This vinyl sulfoxide reacted in high yields and with very high regioselectivities and stereoselectivities with a wide variety of 1,3-dienes (10 examples) at low temperature in the presence of Eu(fod)3 or TiCl4. Whereas cycloadditions catalyzed by TiCl4 (usually carried out at -78-degrees-C) occurred with complete regioselectivity, endo selectivity, and pi-facial selectivity, the cycloaddition catalyzed by Eu(fod)3 (usually performed at 0-degrees-C) also occurred with very high regioselectivity and pi-facial selectivity, but with low endo selectivity. Interestingly, all the adducts (excepting the adducts from cyclopentadiene) are unstable at room temperature, undergoing spontaneous sulfinyl elimination to give 1,3-cyclohexadienes 7 and/or 1,4-cyclohexadienes 11, in excellent yields. Regardless of the catalyst, compounds 7 showed a very high optical purity (ee greater-than-or-equal-to 96%). Finally, some models based on the conformational equilibrium of vinyl sulfoxide 3 have been proposed to explain the observed stereoselectivities.

  DOI：

  10.1021/jo00085a043

文献信息

• Hard acid and soft nucleophile systems. 3. Dealkylation of esters with aluminum halide-thiol and aluminum halide-sulfide systems
  作者：Manabu Node、Kiyoharu Nishide、Midori Sai、Kaoru Fuji、Eiichi Fujita

  DOI：10.1021/jo00323a004

  日期：1981.5
• Monitoring of Phthalic Acid Monoesters in River Water by Solid-Phase Extraction and GC-MS Determination
  作者：Toshinari Suzuki、Kumiko Yaguchi、Sukeji Suzuki、Tetsuya Suga

  DOI：10.1021/es001860i

  日期：2001.9.1

  An analytical method for monitoring 10 phthalic acid monoesters in river water was investigated by solid-phase extraction, methylation with diazomethane, and GCMS. Two cartridge-type solid phases packed with octadesyl-coated silica (C-18) and styrenedivinyl polymer (PS-2) and one disk-type solid phase made from octadesyl-coated styrene-divinylbenzene polymer (SDB-XD) were investigated in solid-phase extraction. PS-2 gave the highest recoveries of the three solid phases, and recoveries of more than 80% of the monoesters in filtered water samples were obtained at pH 2 to 3 with PS-2 at the spiked level of 0.1 mug L-1, except for monomethyl-phthalate (MMP), in which more than 72% of the monoesters were recovered. For the monoesters in the suspended solids (SS), an acidic methanol extract of SS was added to purified water acidified to pH 2, and the monoesters were extracted with PS-2. The recoveries of the monoesters in SS were more than 80%, but the recoveries of MMP were more than 57%. The method detection limit (MDL) of each phthalic acid monoester in 500 mL of water sample and in 2 mg of dry weight of SS ranged from 0.010 to 0.030 mug L-1 and from 1 to 11 mug g(-1) respectively. Monitoring of phthalic acid monoesters in the Tama River in Tokyo was conducted every month from March 1999 to February 2000 using the present method. MMP, mono-n-butyl-phthalate (MBP), and mono-(2-ethylhexyl)-phthalate (MEHP)were detected at concentrations of 0.030-0.0340, 0.010-0.480, and 0.010-1.30 mug L-1, respectively, in the filtered water samples but were not detected in SS. Dim ethyl-phthalate (DMP), di-n-butyl-phthalate (DBP), and di-(2-ethylhexyl)-phthalate (DEHP) were detected in the river water at concentrations of 0.010-0.092, 0.008-0.540, and 0.013-3.60 Pg L-1, respectively. Diethyl-, di-iso-butyl-, and benzylbutyl-phthalates were also detected at concentrations of nanograms per liter, whereas the corresponding monoesters did not appear. The concentrations of MBP and MEHP in the river water were slightly lower than those of the corresponding diesters at the majority of sampling sites and sampling times.
• POLY LACTIC ACID-CONTAINING FILM OR SHEET, AND METHOD FOR MANUFACTURING THEREOF
  申请人：Senda Hiroki

  公开号：US20120046402A1

  公开（公告）日：2012-02-23

  Provided are a film or sheet composed of a resin composition that includes a poly lactic acid (A), an acidic functional group-modified olefinic polymer (B) including an acidic functional group and having an acid value of 10 to 70 mg KOH/g and a weight average molecular weight of 10,000 to 80,000, a tetrafluoroethylene polymer (C), and a dicarboxylic acid ester-containing plasticizer (D) containing a compound of General Formula (1) and in which the dicarboxylic acid ester-containing plasticizer (D) is included in an amount of 8 parts by weight or more and less than 40 parts by weight based on 100 parts by weight of the poly lactic acid (A), and a method for manufacturing the film or sheet by melt film formation. Each sign in Formula is as described in the specification.
• ENVIRONMENTALLY-FRIENDLY HYDROAZIDATION OF OLEFINS
  申请人：GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC.

  公开号：US20210284601A1

  公开（公告）日：2021-09-16

  The present invention provides processes for the synthesis of organic azides, intermediates for the production thereof, and compositions related thereto.
• US4450250A
  申请人：——

  公开号：US4450250A

  公开（公告）日：1984-05-22