3-phenylbenzyl acetate | 82804-36-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-phenylbenzyl acetate
• 英文别名: (3-Phenylphenyl)methyl acetate
• CAS: 82804-36-2
• 化学式: C₁₅H₁₄O₂
• 分子量: 226.275
• InChiKey: NLGMXVVDTYXMDM-UHFFFAOYSA-N

物化性质

• 沸点：
  335.8±11.0 °C(Predicted)
• 密度：
  1.090±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  3-phenylbenzyl acetate 在 盐酸 作用下， 以 甲醇 为溶剂， 反应 2.0h， 以93%的产率得到3-联苯甲醇
  参考文献：
  名称：

  Directional probes of the hydrophobic component of the aromatic ring binding site of norepinephrine N-methyltransferase

  摘要：

  We investigated the directional nature of the bulk tolerance and hydrophobic binding in the aromatic ring binding region of the active site of norepinephrine N-methyltransferase (NMT) by comparing the substrate and inhibitor activities of m- and p-phenyl-substituted derivatives of amphetamine, phenylethanolamine, and alpha-methylbenzylamine. The para isomers of amphetamine and phenylethanolamine displayed significantly greater activities as inhibitor and substrate, respectively, than the meta isomers, which indicated that the bulk tolerance was near the para position. For benzylamines, the greatest inhibitory activity was observed for the meta isomer, demonstrating a significant difference in the binding requirements for phenylethylamines and benzylamines. These findings are consistent with a two-state model for the NMT active site that has been proposed elsewhere to account for its ability to bind both benzylamines and phenylethylamines in a fully extended side-chain conformation.

  DOI：

  10.1021/jm00352a021
• 作为产物：
  描述：

  3-甲基联苯 在 N-溴代丁二酰亚胺(NBS) 、 过氧化氢苯甲酰 作用下， 以 四氯化碳 、 N,N-二甲基甲酰胺 为溶剂， 反应 11.0h， 生成 3-phenylbenzyl acetate
  参考文献：
  名称：

  Directional probes of the hydrophobic component of the aromatic ring binding site of norepinephrine N-methyltransferase

  摘要：

  We investigated the directional nature of the bulk tolerance and hydrophobic binding in the aromatic ring binding region of the active site of norepinephrine N-methyltransferase (NMT) by comparing the substrate and inhibitor activities of m- and p-phenyl-substituted derivatives of amphetamine, phenylethanolamine, and alpha-methylbenzylamine. The para isomers of amphetamine and phenylethanolamine displayed significantly greater activities as inhibitor and substrate, respectively, than the meta isomers, which indicated that the bulk tolerance was near the para position. For benzylamines, the greatest inhibitory activity was observed for the meta isomer, demonstrating a significant difference in the binding requirements for phenylethylamines and benzylamines. These findings are consistent with a two-state model for the NMT active site that has been proposed elsewhere to account for its ability to bind both benzylamines and phenylethylamines in a fully extended side-chain conformation.

  DOI：

  10.1021/jm00352a021

文献信息

• Resin composition, method of its composition, and cured formulation
  申请人：NIPPON SHOKUBAI CO., LTD.

  公开号：EP1626065A1

  公开（公告）日：2006-02-15

  It is an object of the present invention to provide a resin composition which can form cured formulations having various excellent properties such as an insulating property, thermal shock resistance, moldability/formability and strength, and exhibit an excellent appearance inwhich transparency is enhanced, a resin composition whose cured thin film has excellent flame retardancy, good mechanical property and heat resistance, a dispersing element containing an inorganic microfine particle which can give a flame retardancy to a resin, to which the inorganic microfine particle is added, and can reduce a hygroscopic property to the extent possible, a method for producing the same and a cured formulation obtained by using the resin composition. The present invention relates to a resin composition comprising a compound having at least one of a glycidyl group and/or an epoxy group and an inorganic microfine particle, a resin composition comprising three components of a phenolic compound, a compound having at least one of a glycidyl group and/or an epoxy group and an inorganic microfine particle, a flame retardant resin composition comprising a polyhydric phenol and an inorganic microfine particle, and a dispersing element containing an inorganic microfine particle obtained by a hydrolysis condensation reaction of alkoxide and/or metal carboxylate in a dispersion medium.

  本发明的目的是提供一种树脂组合物，该树脂组合物可形成具有各种优异性能（如绝缘性、抗热震性、成型性/可成形性和强度）的固化配方，并表现出优异的外观（其中透明度得到提高）；一种树脂组合物，该树脂组合物的固化薄膜具有优异的阻燃性、本发明涉及一种树脂组合物，其固化薄膜具有优异的阻燃性、良好的机械性能和耐热性；一种含有无机微细颗粒的分散元素，该分散元素可使添加了无机微细颗粒的树脂具有阻燃性，并可尽可能降低吸湿性；一种生产方法；以及一种通过使用该树脂组合物获得的固化配方。本发明涉及一种树脂组合物，该树脂组合物由至少一个具有缩水甘油基和/或环氧基的化合物和无机微细颗粒组成；一种树脂组合物，该树脂组合物由酚类化合物、至少一个具有缩水甘油基和/或环氧基的化合物和无机微细颗粒三部分组成、一种阻燃树脂组合物，包括一种多羟基酚和一种无机微细颗粒，以及一种含有无机微细颗粒的分散元件，该无机微细颗粒是通过烷氧基和/或金属羧酸盐在分散介质中的水解缩合反应获得的。
• Resin Composition for Optical Packaging Material and Process for Preparing the Same, and Optical Packaging Material, Optical Packaging Component, and Optical Module
  申请人：Sugioka Takuo

  公开号：US20090010603A1

  公开（公告）日：2009-01-08

  To provide to a resin composition for an optical packaging material having a coefficient of thermal expansion approximately same as that of quartz and Pyrex (registered trade name) and capable of providing an optical packaging material exhibiting excellent flame retardancy and an optical packaging component, and an optical module and its production method. A molded body, an optical packaging component and an optical module having a low coefficient of thermal expansion and excellent flame retardancy can be obtained using a resin composition for an optical packaging material comprising a resin and inorganic fine particles which are made of a hydrolyzed condensate compound of an alkoxide compound and/or a carboxylic acid salt compound and have an average radius of gyration of 50 nm or smaller.
• SILANE COMPOUND, PRODUCTION METHOD THEREOF, AND RESIN COMPOSITION CONTAINING SILANE COMPOUND
  申请人：Sugioka Takuo

  公开号：US20100317774A1

  公开（公告）日：2010-12-16

  The present invention provides a silane compound which can be preferably used in an electronics application and the like, as a resin composition which is excellent in heat resistance, pressure resistance, water resistance, low moisture absorption property, low dielectric property, mechanical and chemical stability, and heat conductivity and capable of forming cured articles which hardly reduce physical properties even under severe environments such as high temperature and high pressure and high humidity; its production method, and a resin composition containing the silane compound. The silane compound of the present invention provides a silane compound having a siloxane bond and an imido bond, wherein the silane compound comprises a structure unit formed by connecting at least one organic skeleton having an imido bond to a silicon atom forming a siloxane bond, wherein the silane compound is defined by the following average composition formula: XaYbZcSiOd in the formula, X may be same or different and denotes a group including an organic skeleton having an imido bond, represented by the following formula (1); Z may be same or different and denotes an organic group having no imido bond; Y may be same or different and denotes at least one selected from the group consisting of hydrogen atom, hydroxyl group, halogen atom, and OR group; R may be same or different and denotes at least one selected from the group consisting of alkyl, acyl, aryl, and unsaturated aliphatic residual groups and may have a substituent; a is a numeral of 3 or lower but not 0; b is 0 or a numeral less than 3; c is 0 or a numeral less than 3; d is a numeral less than 2 but not 0; and a+b+c+2d=4, in the formula, R 1 denotes at least one structure selected from the group consisting of aromatic, heterocyclic, and alicyclic rings; x and z may be same or different and independently denote an integer of 0 or higher and 5 or lower; and y is 0 or 1.
• METHODS OF CONTROLLING NEONICOTINOID RESISTANT APHIDS
  申请人：Slater Russell

  公开号：US20130231334A1

  公开（公告）日：2013-09-05

  The invention relates to a method of controlling aphids that are resistant to neonicotinoid insecticides, using a trifluoromethylpyri(mi)dine derivative in free form or in agrochemically acceptable salt form as well as the use of compositions comprising said compound to control neonicontinoid resistant insects. In particular the methods relate to controlling neonicotinoid resistant insects in the Aphididae family, that are resistant to one or more neonicotinoid insecticides. Methods of the invention find particular use in controlling neonicotinoid resistant insects in crops of useful plants. Furthermore, the invention extends to methods of controlling plant viruses spread by neonicotinoid resistant insects.
• US7723407B2
  申请人：——

  公开号：US7723407B2

  公开（公告）日：2010-05-25