4-氯-2,3'-联吡啶 | 31860-66-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 中文名称: 4-氯-2,3'-联吡啶
• 英文名称: 4-Chloro-2,3'-bipyridine
• 英文别名: 4-chloro-2-pyridin-3-ylpyridine
• CAS: 31860-66-9
• 化学式: C₁₀H₇ClN₂
• 分子量: 190.632
• InChiKey: CDQMMWWCMQSUJF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  25.8
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-氯-2,3'-联吡啶 在 乙酸酐 、 间氯过氧苯甲酸 作用下， 以 氯仿 为溶剂， 反应 36.0h， 生成 4-chloro-2,3'-bipyrid-2'-one
  参考文献：
  名称：

  从hoplonemertine海蠕虫中分离出错误提议的四吡啶的全合成

  摘要：

  使用钯催化的交叉偶联反应首次合成了Quetrpyridine 1。它的质子NMR谱图表明，它不是从1976年从奈梅汀海生蠕虫中分离出来的天然产物奈默特林。

  DOI：

  10.1016/0040-4020(95)00698-8
• 作为产物：
  描述：

  N-[2,3'-Bipyridin]-4-ylnitramide 以35%的产率得到
  参考文献：
  名称：

  ABDULLAEV, SH. V.;KURBATOV, YU. V.;SAXIBIAZAROV, M., FIZ.-XIM. ISSLED. SINTET. I PRIROD. SOEDIN., SAMARKAND, 1984, 6-8

  摘要：

  DOI：

文献信息

• TBAF-Catalysed silver oxide-mediated cross-coupling of functional trimethysilylpyridines: access to arylpyridines and bihetaryl compounds
  作者：Frédéric Louërat、Heather Tye、Spencer Napier、Michael Garrigou、Mark Whittaker、Philippe C. Gros

  DOI：10.1039/c0ob00710b

  日期：——

  The concomitant use of silver oxide and catalytic amount of TBAF allowed the efficient and chemoselective coupling of readily available 4-chloro- and 4-methyl-2-trimethyl-silyl-pyridines with heteroaromatic and aromatic halides. Based on control experiments, a mechanism involving the formation of a pyridylsilver intermediate and TBAF recycling is postulated.

  银氧化物和催化量的TBAF并用，使得容易获得的4-氯和4-甲基-2-三甲基硅基吡啶与杂芳香族和芳香族卤化物的高效且化学选择性偶联成为可能。基于对照实验，推测了一个涉及吡啶银中间体形成及TBAF再循环的机制。
• COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC DEVICE USING SAME, AND ELECTRONIC DEVICE THEREOF
  申请人：DUK SAN NEOLUX CO., LTD.

  公开号：US20190300535A1

  公开（公告）日：2019-10-03

  Provided are an organic electronic element and an electronic device thereof, the organic electronic element being capable of achieving high light-emitting efficiency and a low driving voltage, and can also greatly improve the lifespan of the element by using a compound of the present invention as a phosphorescent host material.

  提供了一种有机电子元件及其电子设备，该有机电子元件能够实现高发光效率和低驱动电压，并且通过使用本发明的化合物作为荧光主体材料，还可以极大地提高元件的寿命。
• Revised Structure and Convergent Synthesis of Nemertelline, the Neurotoxic Quaterpyridine Isolated from the Hoplonemertine Sea Worm
  作者：Michael P. Jr. Cruskie、John A. Zoltewicz、Khalil A. Abboud

  DOI：10.1021/jo00128a021

  日期：1995.11

  The correct structure of the quaterpyridine nemertelline first isolated from hoplonemertine sea worms has been identified as 2 (3,2':3',4 '':2 '',3triple prime-quaterpyridine). The natural product was synthesized using palladium(0)-catalyzed cross-coupling of 3-(tributylstannyl)-2,3'-bipyridine (3) and 4-chloro-2,3'-bipyridine (4). The bipyridines were prepared in the presence of the Pd catalyst by cross-coupling 2-bromo-3-(tributylstannyl)pyridine (5) and 2,4-dichloropyridine with 3-diethyl(pyridyl)borane, respectively. X-ray analysis confirmed the structure of 2 and provided its conformation in the solid state. The proton NMR spectrum of 2 identifies it as the natural product first reported in 1976.
• [EN] COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC DEVICE USING SAME, AND ELECTRONIC DEVICE THEREOF<br/>[FR] COMPOSÉ POUR ÉLÉMENT ÉLECTRONIQUE ORGANIQUE, DISPOSITIF ÉLECTRONIQUE ORGANIQUE L'UTILISANT ET DISPOSITIF ÉLECTRONIQUE ASSOCIÉ<br/>[KO] 유기전기소자용 화합물, 이를 이용한 유기전기소자 및 그 전자 장치
  申请人：DUK SAN NEOLUX CO LTD

  公开号：WO2018012781A1

  公开（公告）日：2018-01-18

  본 발명에 따른 화합물을 인광 호스트 물질로 이용함으로써, 유기전기소자의 높은 발광효율, 낮은 구동전압을 달성할 수 있으며, 또한 소자의 수명을 크게 향상시킬 수 있는 유기전기소자, 그 전자장치를 제공한다.
• Total synthesis of the incorrectly proposed quaterpyridine isolated from the hoplonemertine sea worm
  作者：John A. Zoltewicz、Michael P. Cruskie

  DOI：10.1016/0040-4020(95)00698-8

  日期：1995.10

  Quaterpyridine 1 was synthesized for the first time using palladium-catalyzed cross-coupling reactions. Its proton NMR spectrum shows that is not the natural product called nemertelline isolated from nemertine marine worms as claimed in 1976.

  使用钯催化的交叉偶联反应首次合成了Quetrpyridine 1。它的质子NMR谱图表明，它不是从1976年从奈梅汀海生蠕虫中分离出来的天然产物奈默特林。