N,N-二(2-羟基乙基)己酰胺 | 29752-80-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: N,N-二(2-羟基乙基)己酰胺
• 英文名称: hexanoyl diethanolamide
• 英文别名: N,N-Bis(2-hydroxyethyl)hexanamide
• CAS: 29752-80-5
• 化学式: C₁₀H₂₁NO₃
• 分子量: 203.282
• InChiKey: JTLQQZSDVWPHLD-UHFFFAOYSA-N

物化性质

• 沸点：
  366.8±27.0 °C(Predicted)
• 密度：
  1.053±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  14
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  60.8
• 氢给体数：
  2
• 氢受体数：
  3

安全信息

• 海关编码：
  2924199090

反应信息

• 作为反应物：
  描述：

  N,N-二(2-羟基乙基)己酰胺 在 Candida antarctica lipase 作用下， 以 乙腈 为溶剂， 反应 24.0h， 生成 二乙醇胺 、 己酸
  参考文献：
  名称：

  脂肪酶催化的脂肪酸二乙醇酰胺的合成。

  摘要：

  二乙醇酰胺是非离子型乳化剂，广泛用于化妆品等行业和用作缓蚀剂。南极假丝酵母脂肪酶（Novozym 435）用于催化各种脂肪酸与二乙醇胺的酰胺化反应。脂肪酸，金属离子和水的含量影响二乙醇酰胺的收率。己酸是所有酰基供体中最好的底物。在50摄氏度和250 rpm的脂肪酶催化下，与90 mM脂肪酸和360 mM二乙醇胺在乙腈中进行脂肪酶催化反应24小时后，得到的己酰基二乙醇酰胺（HADEA），月桂酰基二乙醇酰胺（LADEA）和油酰基二乙醇酰胺（OADEA）的产率分别为76.5、49.5和12.1％。添加1 mM金属盐可提高HADEA和LADEA的产量。动力学分析表明，脂肪酶催化反应中HADEA和LADEA的产率主要与正向反应常数k（1）的速率有关。发现无水酶对于酰胺化反应是最好的。对酶操作稳定性的研究表明，南极衣原体脂肪酶分别保留了HADEA和LADEA合成的初始活性的95％和85％（即使重复使用

  DOI：

  10.1021/jf0107858
• 作为产物：
  描述：

  二乙醇胺 、 己酸 在 1-羟基苯并三唑 、 三乙胺 、 盐酸-N-乙基-Nˊ-(3-二甲氨基丙基)碳二亚胺 作用下， 以 二氯甲烷 为溶剂， 反应 0.25h， 生成 N,N-二(2-羟基乙基)己酰胺
  参考文献：
  名称：

  低分子量基于PEI的生物可降解脂聚合物作为基因传递载体†

  摘要：

  非病毒基因载体在基因治疗的发展中起着重要作用。在本报告中，将不同的疏水链引入基于低分子量（LMW）PEI的可生物降解的低聚物，以形成一系列脂聚合物（LP），并研究了它们的结构-活性关系。结果表明，这九种聚合物可以很好地凝聚质粒DNA，以形成具有适当大小（120–250 nm）和正电动势（+ 25–40 V）的纳米粒子。进行了体外实验，发现在A549细胞中，在有/无血清的情况下，在聚合物/ DNA重量比为0.8的情况下，LP2显示出高得多的转染效率。

  DOI：

  10.1039/c2ob27211c

文献信息

• Process for producing polyolefin
  申请人：MITSUI CHEMICALS, INC.

  公开号：EP1348719A1

  公开（公告）日：2003-10-01

  A process for producing a polyolefin according to the present invention comprises (co) polymerizing one or two or more α-olefins in a vapor phase in a fluidized-bed reactor, wherein the concentration of (A) a saturated aliphatic hydrocarbon in the fluidized bed reactor is 1 mol% or more and at least one compound selected from (B) an aliphatic amide and (C) a nonionic surfactant constituted only of carbon, oxygen and hydrogen atoms is made to exist in the reactor. The present invention can provide a process for producing a polyolefin, the process ensuring that the prevention of clogging caused by the generation of sheet or block polymers and a high efficiency of the production of a polyolefin due to good catalytic activity can be accomplished at the same time and also having superb continuous productivity.

  根据本发明的一种生产聚烯烃的工艺包括（共）在流化床反应器中以气相聚合一种或两种或两种以上的α-烯烃，其中流化床反应器中（A）饱和脂肪族烃的浓度为1摩尔％或更高，并使至少一种选自（B）脂肪族酰胺和（C）仅由碳原子、氧原子和氢原子构成的非离子表面活性剂的化合物存在于反应器中。本发明可提供一种生产聚烯烃的工艺，该工艺可确保同时实现防止因生成片状或块状聚合物而造成的堵塞，以及因良好的催化活性而实现聚烯烃的高效生产，并具有极高的连续生产率。
• SOLID CATALYST FOR OLEFIN POLYMERIZATION, OLEFIN POLYMERIZATION METHOD, AND OLEFIN POLYMER PARTICLE PRODUCED BY THE METHOD
  申请人：Mitsui Chemicals, Inc.

  公开号：EP2096126A1

  公开（公告）日：2009-09-02

  An object of the present invention is to provide solid catalyst component for manufacturing an olefin polymer having an excellent particulate morphology without the concern of causing fouling, and a polymerization of olefin in the presence of said solid catalyst component. A solid catalyst (K) for olefin polymerization of the invention is characterized by meeting the following requirements [1] and [2]: [1] a loss of ignition is 30 wt% or less as measured on a differential thermogravimeter; and [2] after treating the catalyst with water vapor of room temperature and then contacting it with acetonitrile, a component eluted into the acetonitrile comprises a compound having a molecular skeleton represented by the following general formula [I]. (R in the above formula [I] is a hydrogen atom or an alkyl group having 1 to 12 carbon atoms.)

  本发明的目的是提供用于制造烯烃聚合物的固体催化剂组分，该催化剂组分具有优异的微粒形态，且不会造成堵塞，并可在所述固体催化剂组分存在下进行烯烃聚合。 本发明用于烯烃聚合的固体催化剂（K）的特点是满足以下要求[1]和[2]： [1）在差热分析仪上测量的着火损失为 30 wt%或更低；以及 [2]用室温水蒸气处理催化剂，然后使其与乙腈接触，洗脱到乙腈中的组分包括具有以下通式[I]表示的分子骨架的化合物。 (上式[I]中的 R 是氢原子或具有 1 至 12 个碳原子的烷基）。
• PLANT GROWTH PROMOTER ASSOCIATED WITH POTATO CYST NEMATODE
  申请人：TOKAI UNIVERSITY EDUCATIONAL SYSTEM

  公开号：EP2258182A1

  公开（公告）日：2010-12-08

  A growth promoter according to the present invention that can be applied to a plant other than solanaceous plants is a plant growth promoter utilizing potato cyst nematodes and contains a fatty acid dialkanolamide represented by the following general formula (1) as a substance that acts on the potato cyst nematodes:         R-CO-N(-R'-OH)(-R"-OH)     (1) (in the general formula (1), R represents an alkyl group that has 1 to 20 carbon atoms and may be substituted, and R' and R" may be the same or different from each other and each represent an alkylene group that has 1 to 10 carbon atoms and may be substituted). When the plant growth promoter of the present invention is sprayed on the soil where the eggs of potato cyst nematodes are present, potato cyst nematodes hatched by the effect of the above-described fatty acid dialkanolamide contained in the plant growth promoter promote the growth of a non-host plant.

  根据本发明，一种可用于茄科植物以外的植物的生长促进剂是一种利用马铃薯胞囊线虫的植物生长促进剂，它含有一种由下式通式（1）代表的脂肪酸二烷醇酰胺作为对马铃薯胞囊线虫起作用的物质： R-Co-N(-R'-OH)(-R"-OH) (1) (在通式（1）中，R 代表具有 1 至 20 个碳原子且可被取代的烷基，R'和 R "可以相同或不同，且各自代表具有 1 至 10 个碳原子且可被取代的亚烷基）。当将本发明的植物生长促进剂喷洒在存在马铃薯胞囊线虫卵的土壤中时，在植物生长促进剂中所含的上述脂肪酸二坎醇酰胺的作用下孵化的马铃薯胞囊线虫会促进非寄主植物的生长。
• LUBRICATING OIL COMPOSITION, AND SLIDING MECHANISM USING LUBRICATING OIL COMPOSITION
  申请人：Idemitsu Kosan Co., Ltd

  公开号：EP2826844A1

  公开（公告）日：2015-01-21

  Disclosed is a lubricating oil composition for low-friction sliding materials, which is used in a sliding mechanism where a DLC film containing hydrogen in an amount of from 5 atom% to 50 atom% is formed on at least one sliding surface. The lubricating oil composition contains, in the lubricant base oil therein and based on the total amount of the composition, (A) an organic zinc dithiophosphate in an amount of from 0.005% by mass to 0.12% by mass in terms of the phosphorus concentration therein, (B) an amide-based friction-reducing agent in an amount of from 0.05% by mass to 5.0% by mass, and (C) an alkaline earth metal salicylate-based detergent and/or an alkaline earth metal sulfonate-based detergent in an amount of from 0.05% by mass to 0.5o by mass in terms of the alkaline earth metal concentration therein.

  本发明公开了一种用于低摩擦滑动材料的润滑油组合物，该组合物用于在至少一个滑动表面上形成含氢量为 5 原子％至 50 原子％的 DLC 膜的滑动机构中。 该润滑油组合物在其中的润滑油基础油中，根据组合物的总量，含有 (A) 有机二硫代磷酸锌，以其中的磷浓度计，含量为 0.005% （质量分数）至 0.12% （质量分数）；(B) 酰胺基减摩剂，含量为 0.05% (质量)至 5.0% (质量)，以及 (C) 碱土金属水杨酸酯类洗涤剂和/或碱土金属磺酸盐类洗涤剂，以其中碱土金属浓度计，用量为 0.05% (质量)至 0.5o (质量)。
• Plant Growth Promoter Utilizing Potato Cyst Nematode
  申请人：Fukuzawa Akio

  公开号：US20100331189A1

  公开（公告）日：2010-12-30

  A growth promoter according to the present invention that can be applied to a plant other than solanaceous plants is a plant growth promoter utilizing potato cyst nematodes and contains a fatty acid dialkanolamide represented by the following general formula (1) as a substance that acts on the potato cyst nematodes: R—CO—N(—R′—OH)(—R″—OH)  (1) (in the general formula (1), R represents an alkyl group that has 1 to 20 carbon atoms and may be substituted, and R′ and R″ may be the same or different from each other and each represent an alkylene group that has 1 to 10 carbon atoms and may be substituted). When the plant growth promoter of the present invention is sprayed on the soil where the eggs of potato cyst nematodes are present, potato cyst nematodes hatched by the effect of the above-described fatty acid dialkanolamide contained in the plant growth promoter promote the growth of a non-host plant.