2-morpholin-4-yl-4-oxo-4H-chromen-8-yl trifluoromethanesulfonate | 351002-11-4

物质功能分类

医药中间体 - 原料药中间体

分子结构分类

有机化合物 - 有机杂环化合物 - 苯并吡喃

中文名称

——

中文别名

——

英文名称

2-morpholin-4-yl-4-oxo-4H-chromen-8-yl trifluoromethanesulfonate

英文别名

trifluoromethanesulfonic acid 2-(morpholin-4-yl)-4-oxo-4H-chromen-8-yl ester；trifluoro-methanesulfonic acid 2-morpholin-4-yl-4-oxo-4H-chromen-8-yl ester；(2-morpholin-4-yl-4-oxochromen-8-yl) trifluoromethanesulfonate

2-morpholin-4-yl-4-oxo-4H-chromen-8-yl trifluoromethanesulfonate化学式

CAS

351002-11-4

化学式

C₁₄H₁₂F₃NO₆S

mdl

——

分子量

379.314

InChiKey

PQTXIVHYFSFWFT-UHFFFAOYSA-N

BEILSTEIN

——

EINECS

——

物化性质

熔点：

174-175 °C(Solv: ethyl acetate (141-78-6))
沸点：

473.0±45.0 °C(Predicted)
密度：

1.588±0.06 g/cm3(Predicted)

计算性质

辛醇/水分配系数(LogP)：

2.3
重原子数：

25
可旋转键数：

3
环数：

3.0
sp3杂化的碳原子比例：

0.36
拓扑面积：

90.5
氢给体数：

0
氢受体数：

10

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
4H-1-苯并吡喃-4-酮,8-羟基-2-(4-吗啉基)-	8-hydroxy-2-morpholin-4-yl-4H-chromen-4-one	130735-95-4	C₁₃H₁₃NO₄	247.251
——	8-methoxy-2-morpholin-4-yl-4H-chromen-4-one	130766-15-3	C₁₄H₁₅NO₄	261.277
——	8-allyloxy-2-(morpholin-4-yl)chromen-4-one	141307-92-8	C₁₆H₁₇NO₄	287.315

下游产品

中文名称	英文名称	CAS号	化学式	分子量
4H-1-苯并吡喃-4-酮,8-羟基-2-(4-吗啉基)-	8-hydroxy-2-morpholin-4-yl-4H-chromen-4-one	130735-95-4	C₁₃H₁₃NO₄	247.251
——	8-(4-Methoxyphenyl)-2-(morpholin-4-yl)-4H-1-benzopyran-4-one	503468-69-7	C₂₀H₁₉NO₄	337.375
——	8-(3-Hydroxyphenyl)-2-morpholin-4-ylchromen-4-one	503468-79-9	C₁₉H₁₇NO₄	323.348
——	8-(4-phenoxyphenyl)-2-morpholin-4-yl-4H-chromen-4-one	——	C₂₅H₂₁NO₄	399.446
2-吗啉代-8-苯基色酮	LY 294002	154447-36-6	C₁₉H₁₇NO₃	307.349
——	8-(3-(furan-3-yl)phenyl)-2-morpholino-4H-chromen-4-one	1071444-89-7	C₂₃H₁₉NO₄	373.408
——	8-(4-fluorophenyl)-2-morpholin-4-yl-4H-chromen-4-one	——	C₁₉H₁₆FNO₃	325.339
——	8-(biphenyl-3-yl)-2-morpholino-4H-chromen-4-one	503468-73-3	C₂₅H₂₁NO₃	383.447
——	2-morpholino-8-(3-(pyridin-4-yl)phenyl)-4H-chromen-4-one	912844-32-7	C₂₄H₂₀N₂O₃	384.434
——	8-(2-chlorophenyl)-2-morpholin-4-yl-4H-chromen-4-one	——	C₁₉H₁₆ClNO₃	341.794
——	8-(2-methoxyphenyl)-2-morpholin-4-yl-4H-chromen-4-one	——	C₂₀H₁₉NO₄	337.375
——	8-(4-(hydroxymethyl)phenyl)-2-morpholino-4H-chromen-4-one	503468-78-8	C₂₀H₁₉NO₄	337.375
——	8-Dibenzofuran-4-yl-2-morpholin-4-ylchromen-4-one	503468-92-6	C₂₅H₁₉NO₄	397.43
——	2-morpholino-8-(3-(pyrimidin-5-yl)phenyl)-4H-chromen-4-one	1071444-96-6	C₂₃H₁₉N₃O₃	385.422
8-(4-氨基苯基)-2-(4-吗啉基)-4H-1-苯并吡喃-4-酮	PI 828	942289-87-4	C₁₉H₁₈N₂O₃	322.364
——	2-morpholino-8-(3-(pyridin-2-yl)phenyl)-4H-chromen-4-one	912844-39-4	C₂₄H₂₀N₂O₃	384.434
——	8-(3-(1H-pyrrol-3-yl)phenyl)-2-morpholino-4H-chromen-4-one	1071444-90-0	C₂₃H₂₀N₂O₃	372.423
——	8-(3-(furan-2-yl)phenyl)-2-morpholino-4H-chromen-4-one	1071444-88-6	C₂₃H₁₉NO₄	373.408
——	2-Morpholin-4-yl-8-thiophen-3-ylchromen-4-one	503468-85-7	C₁₇H₁₅NO₃S	313.377
——	2-morpholino-8-(3-(pyrimidin-2-yl)phenyl)-4H-chromen-4-one	1071444-95-5	C₂₃H₁₉N₃O₃	385.422
——	8-(2-methylphenyl)-2-morpholin-4-yl-4H-chromen-4-one	——	C₂₀H₁₉NO₃	321.376
——	4-(2-morpholino-4-oxo-4H-chromen-8-yl)benzyl 2-amino-4-methylpentanoate	1395832-67-3	C₂₆H₃₀N₂O₅	450.535
——	2-morpholin-4-yl-8-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4H-chromen-4-one	688745-47-3	C₁₉H₂₄BNO₅	357.214
——	2-Morpholin-4-yl-8-thiophen-2-ylchromen-4-one	503468-86-8	C₁₇H₁₅NO₃S	313.377
——	2-morpholino-8-(3-(thiazol-2-yl)phenyl)-4H-chromen-4-one	912844-36-1	C₂₂H₁₈N₂O₃S	390.463
——	8-(3-(5-methylthiophen-2-yl)phenyl)-2-morpholino-4H-chromen-4-one	912844-35-0	C₂₄H₂₁NO₃S	403.502
——	8-(3-(4-methylthiophen-3-yl)phenyl)-2-morpholino-4H-chromen-4-one	912844-38-3	C₂₄H₂₁NO₃S	403.502
——	8-(3-(1-methyl-1H-imidazol-2-yl)phenyl)-2-morpholino-4H-chromen-4-one	912844-34-9	C₂₃H₂₁N₃O₃	387.438
——	8-(3-(5-methylthiophen-3-yl)phenyl)-2-morpholino-4H-chromen-4-one	1071444-85-3	C₂₄H₂₁NO₃S	403.502
——	2-morpholin-4-yl-8-[2-(trifluoromethyl)phenyl]-4H-chromen-4-one	——	C₂₀H₁₆F₃NO₃	375.347
——	8-(3-(3-methylthiophen-2-yl)phenyl)-2-morpholino-4H-chromen-4-one	912844-37-2	C₂₄H₂₁NO₃S	403.502
——	8-(3-(1-methyl-1H-imidazol-5-yl)phenyl)-2-morpholino-4H-chromen-4-one	1071444-92-2	C₂₃H₂₁N₃O₃	387.438
8-(4-二苯并噻吩基)-2-(4-吗啉基)-4H-1-苯并吡喃-4-酮	8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one	503468-95-9	C₂₅H₁₉NO₃S	413.497
——	N-(2-(cyclopropylmethoxy)-4-(2-morpholino-4-oxo-4H-chromen-8-yl)phenyl)-2-morpholinoacetamide	1275599-49-9	C₂₉H₃₃N₃O₆	519.598
——	8-(5-Acetylthiophen-2-yl)-2-morpholin-4-ylchromen-4-one	503468-91-5	C₁₉H₁₇NO₄S	355.414
——	8-Benzo[b]thiophen-2-yl-2-morpholin-4-yl-chromen-4-one	503468-90-4	C₂₁H₁₇NO₃S	363.437
——	N-(2-((3-methyloxetan-3-yl)methoxy)-4-(2-morpholino-4-oxo-4H-chromen-8-yl)phenyl)-2-morpholinoacetamide	1275599-50-2	C₃₀H₃₅N₃O₇	549.624
——	2-morpholino-8-(1-nitrodibenzo[b,d]thiophen-4-yl)-4H-chromen-4-one	881375-80-0	C₂₅H₁₈N₂O₅S	458.494
——	2-morpholin-4-yl-8-(6',7',8',9'-tetrahydrodibenzothiophen-4'-yl)chromen-4-one	——	C₂₅H₂₃NO₃S	417.529
——	7-allyl-8-(dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chromen-4-one	1393905-52-6	C₂₈H₂₃NO₃S	453.562