1,2-二(戊-3-基)苯 | 265132-51-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 1,2-二(戊-3-基)苯
• 英文名称: 1,2-bis(1-ethylpropyl)benzene
• 英文别名: 1,2-bis(3-pentyl)benzene；Benzene, 1,2-bis(1-ethylpropyl)-；1,2-di(pentan-3-yl)benzene
• CAS: 265132-51-2
• 化学式: C₁₆H₂₆
• 分子量: 218.382
• InChiKey: IAQYJMVZUKKQAX-UHFFFAOYSA-N

物化性质

• 沸点：
  278.3±10.0 °C(Predicted)
• 密度：
  0.854±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.3
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1,2-二(戊-3-基)苯 在 硝酸 作用下， 以 乙酸酐 、 溶剂黄146 为溶剂， 以95%的产率得到4-硝基-1,2-二(戊-3-基)苯
  参考文献：
  名称：

  High intensity ultrasound-assisted reduction of sterically demanding nitroaromatics

  摘要：

  Sterically demanding nitroaromatic compounds have been prepared and reduced to their corresponding amines with high intensity ultrasound using hydrazine in the presence of a Raney nickel catalyst. These reactions were dependent on catalyst quality, solvent and ultrasonic amplitude and, in comparison to their silent reactions, proceeded much faster and afforded higher yields. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2005.02.038
• 作为产物：
  描述：

  乙烯 、 邻二甲苯 在 正丁基锂 、 LiK(OCH₂CH₂NMe₂)2 、 magnesium(2-ethoxyethylate)2 作用下， 以 various solvent(s) 为溶剂， 20.0~80.0 ℃ 、1.01 MPa 条件下， 反应 24.5h， 以61%的产率得到1,2-二(戊-3-基)苯
  参考文献：
  名称：

  乙烯对芳烃的化学选择性催化侧链烷基化生成空间要求高的烷基苯

  摘要：

  DOI：

  10.1021/ja994432p

文献信息

• Aryllithiums with Increasing Steric Crowding and Lipophilicity Prepared from Chlorides in Diethyl Ether. The First Directly Prepared Room-Temperature-Stable Dilithioarenes
  作者：Constantinos G. Screttas、Barry R. Steele、Maria Micha-Screttas、Georgios A. Heropoulos

  DOI：10.1021/ol302672n

  日期：2012.11.16

  A convenient procedure has been developed for the preparation of synthetically useful, room-temperature-stable aryllithiums starting from aryl chlorides and lithium metal. The method provides a route to aryllithiums which have previously not been accessible cleanly or could only be prepared by using more expensive starting materials.
• Synthesis and properties of 1-bromo-2,3,5,6-tetrakis(3-pentyl)benzene: a highly sterically hindered aryl bromide
  作者：Barry R. Steele、Maria Micha-Screttas、Constantinos G. Screttas

  DOI：10.1016/j.tetlet.2004.10.144

  日期：2004.12

  The preparation of 1-bromo-2,3,5,6-tetrakis(3-pentyl)benzene is reported. The H-1 and C-13 NMR spectra indicate the presence of rotational isomers at room temperature which interconvert on heating. Coalescence of the NMR peaks for the methine and methylene aliphatic protons is observed at 100-120degreesC. The conversion of this aryl bromide to the corresponding aryllithium is reported. Similar but less bulky aryl bromides have also been synthesised. (C) 2004 Elsevier Ltd. All rights reserved.
• Chemoselective Catalytic Side-Chain Alkylation of Aromatics by Ethylene Leading to Sterically Demanding Alkylbenzenes
  作者：Barry R. Steele、Constantinos G. Screttas

  DOI：10.1021/ja994432p

  日期：2000.3.1
• High intensity ultrasound-assisted reduction of sterically demanding nitroaromatics
  作者：Georgios A. Heropoulos、Spyros Georgakopoulos、Barry R. Steele

  DOI：10.1016/j.tetlet.2005.02.038

  日期：2005.4

  Sterically demanding nitroaromatic compounds have been prepared and reduced to their corresponding amines with high intensity ultrasound using hydrazine in the presence of a Raney nickel catalyst. These reactions were dependent on catalyst quality, solvent and ultrasonic amplitude and, in comparison to their silent reactions, proceeded much faster and afforded higher yields. (c) 2005 Elsevier Ltd. All rights reserved.